| # | Title | Journal | Year | Citations |
|---|
| 1 | On the Origin of Cancer Metastasis | Critical Reviews in Oncogenesis | 2013 | 797 |
| 2 | Intrinsic and Acquired Resistance to HER2-Targeted Therapies in HER2 Gene-Amplified Breast Cancer: Mechanisms and Clinical Implications | Critical Reviews in Oncogenesis | 2012 | 277 |
| 3 | The role for transforming growth factor-beta (TGF-beta) in human cancer | Critical Reviews in Oncogenesis | 1999 | 241 |
| 4 | Histone Deacetylases and Mechanisms of Regulation of Gene Expression | Critical Reviews in Oncogenesis | 2015 | 209 |
| 5 | Targeting PI3 Kinase/AKT/mTOR Signaling in Cancer | Critical Reviews in Oncogenesis | 2012 | 204 |
| 6 | Light at Night, Chronodisruption, Melatonin Suppression, and Cancer Risk: A Review | Critical Reviews in Oncogenesis | 2007 | 188 |
| 7 | Hepatocyte growth factor: molecular structure, roles in liver regeneration, and other biological functions | Critical Reviews in Oncogenesis | 1992 | 185 |
| 8 | SV40-lnduced Immortalization of Human Cells | Critical Reviews in Oncogenesis | 1994 | 184 |
| 9 | Chemoprevention and Therapy of Cancer by d-Limonene | Critical Reviews in Oncogenesis | 1994 | 181 |
| 10 | Glioblastoma Heterogeneity and Cancer Cell Plasticity | Critical Reviews in Oncogenesis | 2014 | 178 |
| 11 | Resistance to inhibition of cell growth by transforming growth factor-beta and its role in oncogenesis | Critical Reviews in Oncogenesis | 1993 | 145 |
| 12 | Dietary Flavonoid and Cancer Prevention: Evidence and Potential Mechanism | Critical Reviews in Oncogenesis | 1997 | 141 |
| 13 | Anoikis and EMT: Lethal "Liaisons" during Cancer Progression | Critical Reviews in Oncogenesis | 2016 | 139 |
| 14 | The EMT Universe: Space between Cancer Cell Dissemination and Metastasis Initiation | Critical Reviews in Oncogenesis | 2014 | 129 |
| 15 | The Insulin-Like Growth Factor-I Receptor Signaling Pathways Are Important for Tumorigenesis and Inhibition of Apoptosis | Critical Reviews in Oncogenesis | 1997 | 127 |
| 16 | Osteosarcoma Genetics and Epigenetics: Emerging Biology and Candidate Therapies | Critical Reviews in Oncogenesis | 2015 | 126 |
| 17 | The Oncogenic Role of Yin Yang 1 | Critical Reviews in Oncogenesis | 2011 | 126 |
| 18 | Gaucher Disease: A Comprehensive Review | Critical Reviews in Oncogenesis | 2013 | 125 |
| 19 | Downregulation of Gap Junctions in Cancer Cells | Critical Reviews in Oncogenesis | 2006 | 122 |
| 20 | Double role for pyruvate kinase type M2 in the expansion of phosphometabolite pools found in tumor cells | Critical Reviews in Oncogenesis | 1992 | 121 |
| 21 | Gadd45 Stress Sensors in Malignancy and Leukemia | Critical Reviews in Oncogenesis | 2011 | 117 |
| 22 | NK Cells in the Tumor Microenvironment | Critical Reviews in Oncogenesis | 2014 | 116 |
| 23 | Structure and function of eukaryotic proprotein processing enzymes of the subtilisin family of serine proteases | Critical Reviews in Oncogenesis | 1993 | 110 |
| 24 | Resistance to Cell Death and Its Modulation in Cancer Stem Cells | Critical Reviews in Oncogenesis | 2016 | 106 |
| 25 | Colorectal Cancer: A Multipathway Disease | Critical Reviews in Oncogenesis | 2006 | 105 |
| 26 | Steel Factor and c-kit Protooncogene: Genetic Lessons in Signal Transduction | Critical Reviews in Oncogenesis | 1994 | 105 |
| 27 | Stem Cell Marker OCT3/4 in Tumor Biology and Germ Cell Tumor Diagnostics: History and Future | Critical Reviews in Oncogenesis | 2006 | 104 |
| 28 | EGR-1, The Reluctant Suppression Factor: | Critical Reviews in Oncogenesis | 1996 | 104 |
| 29 | Perspectives on c-Myc, Cyclin D1, and Their Interaction in Cancer Formation, Progression, and Response to Chemotherapy | Critical Reviews in Oncogenesis | 2007 | 103 |
| 30 | Multifaceted Modulation of SIRT1 in Cancer and Inflammation | Critical Reviews in Oncogenesis | 2015 | 102 |
| 31 | Cytokine Involvement in Cancer Anorexia/ Cachexia: Role of Megestrol Acetate and Medroxyprogesterone Acetate on Cytokine Downregulation and Improvement of Clinical Symptoms | Critical Reviews in Oncogenesis | 1998 | 101 |
| 32 | NK Cells in Therapy of Cancer | Critical Reviews in Oncogenesis | 2014 | 98 |
| 33 | Gaucher Disease and Malignancy: A Model for Cancer Pathogenesis in an Inborn Error of Metabolism | Critical Reviews in Oncogenesis | 2013 | 96 |
| 34 | The Tumor-Promoting Effect of Wounding: A Possible Role for TGF-β-lnduced Stromal Alterations | Critical Reviews in Oncogenesis | 1994 | 96 |
| 35 | Hypoxia-Induced Signaling Promotes Prostate Cancer Progression: Exosomes Role as Messenger of Hypoxic Response in Tumor Microenvironment | Critical Reviews in Oncogenesis | 2015 | 95 |
| 36 | Signal transduction and gene control: the cAMP pathway | Critical Reviews in Oncogenesis | 1992 | 93 |
| 37 | Biology and Treatment of Rhabdoid Tumor | Critical Reviews in Oncogenesis | 2015 | 89 |
| 38 | Twenty Years on: What Do We Really Know about Ewing Sarcoma and What Is the Path Forward? | Critical Reviews in Oncogenesis | 2015 | 88 |
| 39 | RUNX1 Mutations in Clonal Myeloid Disorders: From Conventional Cytogenetics to Next Generation Sequencing, A Story 40 Years in the Making | Critical Reviews in Oncogenesis | 2011 | 88 |
| 40 | The Cbl Protooncogene Product: From an Enigmatic Oncogene to Center Stage of Signal Transduction | Critical Reviews in Oncogenesis | 1997 | 84 |
| 41 | The epidemiology of thyroid carcinoma | Critical Reviews in Oncogenesis | 1993 | 84 |
| 42 | Myeloid Leukemia in Down Syndrome | Critical Reviews in Oncogenesis | 2011 | 82 |
| 43 | Autophagy and Hallmarks of Cancer | Critical Reviews in Oncogenesis | 2018 | 82 |
| 44 | T and Tn Pancarcinoma Markers: Autoantigenic Adhesion Molecules in Pathogenesis, Prebiopsy Carcinoma-Detection, and Long-Term Breast Carcinoma Immunotherapy | Critical Reviews in Oncogenesis | 1995 | 82 |
| 45 | Hematopoietic receptors of class III receptor-type tyrosine kinases | Critical Reviews in Oncogenesis | 1993 | 79 |
| 46 | Pediatric Rhabdomyosarcoma | Critical Reviews in Oncogenesis | 2015 | 78 |
| 47 | Immunological Cells and Functions in Gaucher Disease | Critical Reviews in Oncogenesis | 2013 | 77 |
| 48 | The role of p21ras in receptor tyrosine kinase signaling | Critical Reviews in Oncogenesis | 1993 | 76 |
| 49 | The Novel Role of Yin Yang 1 in the Regulation of Epithelial to Mesenchymal Transition in Cancer Via the Dysregulated NF-κB/Snail/YY1/RKIP/PTEN Circuitry | Critical Reviews in Oncogenesis | 2011 | 75 |
| 50 | Immunosenescence and Cancer | Critical Reviews in Oncogenesis | 2013 | 75 |
