| # | Title | Journal | Year | Citations |
|---|
| 1 | Limbic system mechanisms of stress regulation: Hypothalamo-pituitary-adrenocortical axis | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2005 | 1,079 |
| 2 | Cytokines and major depression | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2005 | 1,010 |
| 3 | A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2011 | 960 |
| 4 | Evidence for an immune response in major depression: A review and hypothesis | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 1995 | 820 |
| 5 | Drug craving and addiction: integrating psychological and neuropsychopharmacological approaches | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2003 | 676 |
| 6 | Serotonin receptors : their key role in drugs to treat schizophrenia | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2003 | 670 |
| 7 | The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2011 | 547 |
| 8 | Citalopram — Pharmacological profile of a specific serotonin uptake inhibitor with antidepressant activity | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 1982 | 540 |
| 9 | A new view of diabetic retinopathy: a neurodegenerative disease of the eye | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2003 | 535 |
| 10 | Half a century of antipsychotics and still a central role for dopamine D2 receptors | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2003 | 520 |
| 11 | Role of selective serotonin reuptake inhibitors in psychiatric disorders: a comprehensive review | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2003 | 495 |
| 12 | Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2012 | 479 |
| 13 | Inflamed moods: A review of the interactions between inflammation and mood disorders | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2014 | 468 |
| 14 | Role of brain norepinephrine in the behavioral response to stress | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2005 | 462 |
| 15 | The role of pro-inflammatory cytokines in neuroinflammation, neurogenesis and the neuroendocrine system in major depression | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2016 | 448 |
| 16 | Inflammatory processes in Alzheimer's disease | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2003 | 445 |
| 17 | Sexual dimorphism of the developing human brain | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 1997 | 443 |
| 18 | Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2011 | 438 |
| 19 | Monoamine neurocircuitry in depression and strategies for new treatments | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2013 | 432 |
| 20 | Glucocorticoids, cytokines and brain abnormalities in depression | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2011 | 426 |
| 21 | Central monoamines and their role in major depression | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2004 | 407 |
| 22 | Younger people are more vulnerable to stress, anxiety and depression during COVID-19 pandemic: A global cross-sectional survey | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2021 | 398 |
| 23 | Spice drugs are more than harmless herbal blends: A review of the pharmacology and toxicology of synthetic cannabinoids | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2012 | 393 |
| 24 | Homocysteine and folate metabolism in depression | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2005 | 389 |
| 25 | Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2008 | 377 |
| 26 | In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2011 | 369 |
| 27 | COVID-19 pandemic impact on children and adolescents' mental health: Biological, environmental, and social factors | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2021 | 360 |
| 28 | Role of endogenous opioid system in the regulation of the stress response | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2001 | 348 |
| 29 | Reduced levels of NR2A and NR2B subunits of NMDA receptor and PSD-95 in the prefrontal cortex in major depression | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2009 | 340 |
| 30 | Development of the human corpus callosum during childhood and adolescence: A longitudinal MRI study | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 1999 | 338 |
| 31 | An MRI study of the basal ganglia in autism | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 1999 | 336 |
| 32 | Celastrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment for Alzheimer's disease | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2001 | 329 |
| 33 | The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorder | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2011 | 327 |
| 34 | Hippocampal volume deficits associated with exposure to psychological trauma and posttraumatic stress disorder in adults: A meta-analysis | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2010 | 322 |
| 35 | Lymphocytes as a neural probe: potential for studying psychiatric disorders | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2004 | 318 |
| 36 | The effects of omega-3 fatty acids monotherapy in Alzheimer's disease and mild cognitive impairment: A preliminary randomized double-blind placebo-controlled study | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2008 | 313 |
| 37 | Dim light melatonin onset (DLMO): A tool for the analysis of circadian phase in human sleep and chronobiological disorders | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2007 | 307 |
| 38 | The role of pro-inflammatory cytokines in the neuroinflammation and neurogenesis of schizophrenia | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2014 | 304 |
| 39 | Free radicals, antioxidant defense systems, and schizophrenia | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2013 | 299 |
| 40 | Validation criteria for animal models of human mental disorders: Learned helplessness as a paradigm case | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 1986 | 297 |
| 41 | Treatment-refractory obsessive-compulsive disorder: Methodological issues, operational definitions and therapeutic lines | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2006 | 292 |
| 42 | The effect of chronic antidepressant treatment on serum brain-derived neurotrophic factor levels in depressed patients: a preliminary study | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2005 | 282 |
| 43 | Selective participation of the bed nucleus of the stria terminalis and CRF in sustained anxiety-like versus phasic fear-like responses | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2009 | 281 |
| 44 | Withania somnifera: An Indian ginseng | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2008 | 279 |
| 45 | The immune system, depression and the action of antidepressants | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2001 | 278 |
| 46 | A randomized double-blind, placebo-controlled study of the effects of supplementation with highly unsaturated fatty acids on ADHD-related symptoms in children with specific learning difficulties | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2002 | 278 |
| 47 | Psychomotor retardation in depression: Biological underpinnings, measurement, and treatment | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2011 | 278 |
| 48 | A review of peripheral biomarkers in major depression: The potential of inflammatory and oxidative stress biomarkers | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2014 | 276 |
| 49 | Animal models of major depression and their clinical implications | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2016 | 276 |
| 50 | Brain structures and neurotansmitters regulating aggression in cats: implications for human aggression | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2001 | 271 |
