| # | Title | Journal | Year | Citations |
|---|
| 1 | Meta-analysis in clinical trials | Contemporary Clinical Trials | 1986 | 33,020 |
| 2 | Assessing the quality of reports of randomized clinical trials: Is blinding necessary? | Contemporary Clinical Trials | 1996 | 16,054 |
| 3 | Measurement of health status | Contemporary Clinical Trials | 1989 | 3,981 |
| 4 | Optimal two-stage designs for phase II clinical trials | Contemporary Clinical Trials | 1989 | 3,264 |
| 5 | Design of the Women’s Health Initiative Clinical Trial and Observational Study | Contemporary Clinical Trials | 1998 | 2,421 |
| 6 | A note on quantifying follow-up in studies of failure time | Contemporary Clinical Trials | 1996 | 2,072 |
| 7 | Power and sample size calculations | Contemporary Clinical Trials | 1990 | 1,779 |
| 8 | A method for assessing the quality of a randomized control trial | Contemporary Clinical Trials | 1981 | 1,235 |
| 9 | Reproducibility and responsiveness of health status measures statistics and strategies for evaluation | Contemporary Clinical Trials | 1991 | 1,166 |
| 10 | Assessing the quality of randomized controlled trials: An annotated bibliography of scales and checklists | Contemporary Clinical Trials | 1995 | 1,089 |
| 11 | Sequenced treatment alternatives to relieve depression (STAR*D): rationale and design | Contemporary Clinical Trials | 2004 | 898 |
| 12 | Introduction to sample size determination and power analysis for clinical trials | Contemporary Clinical Trials | 1981 | 897 |
| 13 | Power and Sample Size Calculations for Studies Involving Linear Regression | Contemporary Clinical Trials | 1998 | 863 |
| 14 | Design of the prostate, lung, colorectal and ovarian (PLCO) cancer screening trial | Contemporary Clinical Trials | 2000 | 854 |
| 15 | “Proving the null hypothesis” in clinical trials | Contemporary Clinical Trials | 1982 | 828 |
| 16 | Patient compliance with paper and electronic diaries | Contemporary Clinical Trials | 2003 | 773 |
| 17 | Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes | Contemporary Clinical Trials | 2003 | 698 |
| 18 | Do Certain Countries Produce Only Positive Results? A Systematic Review of Controlled Trials | Contemporary Clinical Trials | 1998 | 613 |
| 19 | Publication bias and clinical trials | Contemporary Clinical Trials | 1987 | 589 |
| 20 | Assessing the Quality of Randomized Trials | Contemporary Clinical Trials | 1999 | 556 |
| 21 | Statistical Considerations in the Intent-to-Treat Principle | Contemporary Clinical Trials | 2000 | 543 |
| 22 | The method of minimization for allocation to clinical trials | Contemporary Clinical Trials | 2002 | 539 |
| 23 | The Age-Related Eye Disease Study (AREDS) | Contemporary Clinical Trials | 1999 | 500 |
| 24 | The Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial of the National Cancer Institute: History, organization, and status | Contemporary Clinical Trials | 2000 | 443 |
| 25 | Assessment of blinding in clinical trials | Contemporary Clinical Trials | 2004 | 398 |
| 26 | Analysis of data from multiclinic trials | Contemporary Clinical Trials | 1986 | 394 |
| 27 | Considerations in the Evaluation of Surrogate Endpoints in Clinical Trials | Contemporary Clinical Trials | 2001 | 381 |
| 28 | Recruitment for controlled clinical trials: Literature summary and annotated bibliography | Contemporary Clinical Trials | 1997 | 364 |
| 29 | Cumulating evidence from randomized trials: Utilizing sequential monitoring boundaries for cumulative meta-analysis | Contemporary Clinical Trials | 1997 | 359 |
| 30 | The Childhood Asthma Management Program (CAMP) | Contemporary Clinical Trials | 1999 | 348 |
| 31 | A Primary Prevention Trial Using Nutritional Doses of Antioxidant Vitamins and Minerals in Cardiovascular Diseases and Cancers in a General Population | Contemporary Clinical Trials | 1998 | 332 |
| 32 | Active | Contemporary Clinical Trials | 2001 | 328 |
| 33 | Designs for group sequential tests | Contemporary Clinical Trials | 1984 | 327 |
| 34 | PS power and sample size program available for free on the internet | Contemporary Clinical Trials | 1997 | 299 |
| 35 | Methodology and overt and hidden bias in reports of 196 double-blind trials of nonsteroidal antiinflammatory drugs in rheumatoid arthritis | Contemporary Clinical Trials | 1989 | 295 |
| 36 | The Women’s Health Initiative Memory Study (WHIMS) | Contemporary Clinical Trials | 1998 | 287 |
| 37 | Properties of the urn randomization in clinical trials | Contemporary Clinical Trials | 1988 | 277 |
| 38 | Inclusion of women and minorities in clinical trials and the NIH Revitalization Act of 1993 — The perspective of NIH clinical trialists | Contemporary Clinical Trials | 1995 | 276 |
| 39 | Sample-Size Calculations for the Cox Proportional Hazards Regression Model with Nonbinary Covariates | Contemporary Clinical Trials | 2000 | 265 |
| 40 | Measuring treatment impact: a review of patient-reported outcomes and other efficacy endpoints in approved product labels | Contemporary Clinical Trials | 2004 | 261 |
| 41 | Monitoring clinical trials: Conditional or predictive power? | Contemporary Clinical Trials | 1986 | 257 |
| 42 | Properties of permuted-block randomization in clinical trials | Contemporary Clinical Trials | 1988 | 256 |
| 43 | A randomized trial of the effect of a plant-based dietary pattern on additional breast cancer events and survival: | Contemporary Clinical Trials | 2002 | 249 |
| 44 | SEARCH for Diabetes in Youth: a multicenter study of the prevalence, incidence and classification of diabetes mellitus in youth | Contemporary Clinical Trials | 2004 | 245 |
| 45 | The bivariate continual reassessment method | Contemporary Clinical Trials | 2002 | 242 |
| 46 | Randomization in clinical trials: Conclusions and recommendations | Contemporary Clinical Trials | 1988 | 236 |
| 47 | Recruitment experience in clinical trials: Literature summary and annotated bibliography | Contemporary Clinical Trials | 1987 | 234 |
| 48 | Recruitment in the Coronary Artery Disease Risk Development in Young Adults (Cardia) study | Contemporary Clinical Trials | 1987 | 231 |
| 49 | Stroke Prevention Trial in Sickle Cell Anemia | Contemporary Clinical Trials | 1998 | 228 |
| 50 | An empirical study of the possible relation of treatment differences to quality scores in controlled randomized clinical trials | Contemporary Clinical Trials | 1990 | 227 |
