# | Title | Journal | Year | Citations |
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1 | The expanding universe of T-cell subsets: Th1, Th2 and more | Trends in Immunology | 1996 | 3,410 |
2 | Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon? | Trends in Immunology | 1993 | 2,630 |
3 | The acute phase response | Trends in Immunology | 1994 | 2,592 |
4 | In search of the ‘missing self’: MHC molecules and NK cell recognition | Trends in Immunology | 1990 | 2,377 |
5 | The mechanism of action of cyclosporin A and FK506 | Trends in Immunology | 1992 | 2,114 |
6 | Oxidative stress as a mediator of apoptosis | Trends in Immunology | 1994 | 2,083 |
7 | Mitochondrial control of apoptosis | Trends in Immunology | 1997 | 1,401 |
8 | A TH1→TH2 switch is a critical step in the etiology of HIV infection | Trends in Immunology | 1993 | 1,389 |
9 | The B7 and CD28 receptor families | Trends in Immunology | 1994 | 1,279 |
10 | Circulating adhesion molecules in disease | Trends in Immunology | 1993 | 1,277 |
11 | There is more than one interleukin 1 | Trends in Immunology | 1986 | 1,222 |
12 | The immune system evolved to discriminate infectious nonself from noninfectious self | Trends in Immunology | 1992 | 1,192 |
13 | Human TH1 and TH2 subsets: doubt no more | Trends in Immunology | 1991 | 1,097 |
14 | Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases | Trends in Immunology | 1995 | 1,084 |
15 | Signal transduction through NF-κB | Trends in Immunology | 1998 | 1,045 |
16 | Apoptosis | Trends in Immunology | 1993 | 1,039 |
17 | Biological and clinical aspects of interleukin 6 | Trends in Immunology | 1990 | 1,038 |
18 | Two TNF receptors | Trends in Immunology | 1992 | 1,013 |
19 | Phagocyte recognition of cells undergoing apoptosis | Trends in Immunology | 1993 | 987 |
20 | The major acute phase reactants: C-reactive protein, serum amyloid P component and serum amyloid A protein | Trends in Immunology | 1994 | 977 |
21 | The origin and function of tumor-associated macrophages | Trends in Immunology | 1992 | 966 |
22 | The Th1/Th2 paradigm | Trends in Immunology | 1997 | 935 |
23 | Heat shock proteins and the immune response | Trends in Immunology | 1990 | 933 |
24 | Th 1-type immunity is incompatible with successful pregnancy | Trends in Immunology | 1997 | 905 |
25 | Fas and Fas ligand: lpr and gld mutations | Trends in Immunology | 1995 | 872 |
26 | Interleukin-12 and its role in the generation of TH1 cells | Trends in Immunology | 1993 | 867 |
27 | Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses | Trends in Immunology | 1998 | 864 |
28 | A very high level of crossreactivity is an essential feature of the T-cell receptor | Trends in Immunology | 1998 | 860 |
29 | The production of cytokines by polymorphonuclear neutrophils | Trends in Immunology | 1995 | 857 |
30 | Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells | Trends in Immunology | 1994 | 832 |
31 | T-cell priming by type-1and type-2 polarized dendritic cells: the concept of a third signal | Trends in Immunology | 1999 | 830 |
32 | Human naive and memory T cells | Trends in Immunology | 1988 | 806 |
33 | NKT cells: facts, functions and fallacies | Trends in Immunology | 2000 | 771 |
34 | Induction of TH1 and TH2 responses: a key role for the ‘natural’ immune response? | Trends in Immunology | 1992 | 763 |
35 | Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro | Trends in Immunology | 1991 | 739 |
36 | Oral tolerance: immune mechanisms and treatment of autoimmune diseases | Trends in Immunology | 1997 | 732 |
37 | Endothelial cell interactions with granulocytes: tethering and signaling molecules | Trends in Immunology | 1992 | 730 |
38 | The cytokine network | Trends in Immunology | 1989 | 717 |
39 | Implications for immunosurveillance of altered HLA class I phenotypes in human tumours | Trends in Immunology | 1997 | 708 |
40 | The Th1–Th2 hypothesis of HIV infection: new insights | Trends in Immunology | 1994 | 703 |
41 | The role of IL-10 in crossregulation of TH1 and TH2 responses | Trends in Immunology | 1991 | 702 |
42 | Mast cells as a source of multifunctional cytokines | Trends in Immunology | 1990 | 689 |
43 | Defining criteria for autoimmune diseases (Witebsky's postulates revisited) | Trends in Immunology | 1993 | 681 |
44 | A role for Th1 and Th2 cells in the immunopathogenesis of atopic dermatitis | Trends in Immunology | 1998 | 672 |
45 | Immune interferon: a pleiotropic lymphokine with multiple effects | Trends in Immunology | 1985 | 669 |
46 | Lymphocyte interactions with endothelial cells | Trends in Immunology | 1992 | 669 |
47 | The syntax of immune-neuroendocrine communication | Trends in Immunology | 1994 | 669 |
48 | Human IgG Fc receptor heterogeneity: molecular aspects and clinical implications | Trends in Immunology | 1993 | 666 |
49 | Fibrogenic cytokines: the role of immune mediators in the development of scar tissue | Trends in Immunology | 1991 | 661 |
50 | Haemopoietic receptors and helical cytokines | Trends in Immunology | 1990 | 650 |