| # | Title | Journal | Year | Citations |
|---|
| 1 | Oxygen-induced retinopathy in the mouse | Investigative Ophthalmology and Visual Science | 1994 | 1,187 |
| 2 | In vivo fluorescence of the ocular fundus exhibits retinal pigment epithelium lipofuscin characteristics | Investigative Ophthalmology and Visual Science | 1995 | 653 |
| 3 | Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis | Investigative Ophthalmology and Visual Science | 1995 | 620 |
| 4 | Number of ganglion cells in glaucoma eyes compared with threshold visual field tests in the same persons | Investigative Ophthalmology and Visual Science | 2000 | 529 |
| 5 | Photoreceptor loss in age-related macular degeneration | Investigative Ophthalmology and Visual Science | 1996 | 518 |
| 6 | Morphometric analysis of Bruch's membrane, the choriocapillaris, and the choroid in aging | Investigative Ophthalmology and Visual Science | 1994 | 504 |
| 7 | An SV40-immortalized human corneal epithelial cell line and its characterization | Investigative Ophthalmology and Visual Science | 1995 | 494 |
| 8 | Prevalence and risk factors for refractive errors in adult Chinese in Singapore | Investigative Ophthalmology and Visual Science | 2000 | 454 |
| 9 | Subfoveal fibrovascular membranes in age-related macular degeneration express vascular endothelial growth factor | Investigative Ophthalmology and Visual Science | 1996 | 448 |
| 10 | Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes | Investigative Ophthalmology and Visual Science | 1996 | 447 |
| 11 | Visual attention problems as a predictor of vehicle crashes in older drivers | Investigative Ophthalmology and Visual Science | 1993 | 442 |
| 12 | Pro- and anti-inflammatory forms of interleukin-1 in the tear fluid and conjunctiva of patients with dry-eye disease | Investigative Ophthalmology and Visual Science | 2001 | 438 |
| 13 | Aging of the human retina. Differential loss of neurons and retinal pigment epithelial cells | Investigative Ophthalmology and Visual Science | 1992 | 430 |
| 14 | The X, Y, Z hypothesis of corneal epithelial maintenance | Investigative Ophthalmology and Visual Science | 1983 | 424 |
| 15 | Retinitis pigmentosa. The Friedenwald Lecture | Investigative Ophthalmology and Visual Science | 1993 | 421 |
| 16 | The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells | Investigative Ophthalmology and Visual Science | 2000 | 410 |
| 17 | Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice | Investigative Ophthalmology and Visual Science | 1998 | 409 |
| 18 | Aging of the human photoreceptor mosaic: evidence for selective vulnerability of rods in central retina | Investigative Ophthalmology and Visual Science | 1993 | 408 |
| 19 | The three-dimensional organization of collagen fibrils in the human cornea and sclera | Investigative Ophthalmology and Visual Science | 1991 | 407 |
| 20 | Central corneal endothelial cell changes over a ten-year period | Investigative Ophthalmology and Visual Science | 1997 | 400 |
| 21 | Parental myopia, near work, school achievement, and children's refractive error | Investigative Ophthalmology and Visual Science | 2002 | 393 |
| 22 | Optic disc, cup and neuroretinal rim size, configuration and correlations in normal eyes | Investigative Ophthalmology and Visual Science | 1988 | 391 |
| 23 | Aging human RPE: morphometric analysis of macular, equatorial, and peripheral cells | Investigative Ophthalmology and Visual Science | 1984 | 369 |
| 24 | Retinal pigment epithelial lipofuscin and melanin and choroidal melanin in human eyes | Investigative Ophthalmology and Visual Science | 1986 | 365 |
| 25 | Factors affecting light-adapted pupil size in normal human subjects | Investigative Ophthalmology and Visual Science | 1994 | 362 |
| 26 | VEGF-initiated blood-retinal barrier breakdown in early diabetes | Investigative Ophthalmology and Visual Science | 2001 | 362 |
| 27 | Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma | Investigative Ophthalmology and Visual Science | 2000 | 353 |
| 28 | Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats | Investigative Ophthalmology and Visual Science | 2000 | 342 |
| 29 | Protection of mouse photoreceptors by survival factors in retinal degenerations | Investigative Ophthalmology and Visual Science | 1998 | 340 |
| 30 | Cell loss in the aging retina. Relationship to lipofuscin accumulation and macular degeneration | Investigative Ophthalmology and Visual Science | 1989 | 337 |
| 31 | The macular pigment. II. Spatial distribution in primate retinas | Investigative Ophthalmology and Visual Science | 1984 | 336 |
| 32 | Differential effect of the rd mutation on rods and cones in the mouse retina | Investigative Ophthalmology and Visual Science | 1978 | 333 |
| 33 | Refractive error in children in an urban population in New Delhi | Investigative Ophthalmology and Visual Science | 2002 | 332 |
| 34 | Glial reactivity, an early feature of diabetic retinopathy | Investigative Ophthalmology and Visual Science | 2000 | 330 |
| 35 | Analysis of the macular pigment by HPLC: retinal distribution and age study | Investigative Ophthalmology and Visual Science | 1988 | 327 |
| 36 | Fundus autofluorescence and development of geographic atrophy in age-related macular degeneration | Investigative Ophthalmology and Visual Science | 2001 | 327 |
| 37 | Baseline findings in the Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study | Investigative Ophthalmology and Visual Science | 1998 | 324 |
| 38 | Clinical grading and the effects of scaling | Investigative Ophthalmology and Visual Science | 1991 | 312 |
| 39 | Refractive error in children in a rural population in India | Investigative Ophthalmology and Visual Science | 2002 | 310 |
| 40 | Chronic glaucoma selectively damages large optic nerve fibers | Investigative Ophthalmology and Visual Science | 1987 | 305 |
| 41 | Accumulation of cholesterol with age in human Bruch's membrane | Investigative Ophthalmology and Visual Science | 2001 | 305 |
| 42 | Human optic nerve fiber count and optic disc size | Investigative Ophthalmology and Visual Science | 1992 | 303 |
| 43 | Risk factors for high-risk proliferative diabetic retinopathy and severe visual loss: Early Treatment Diabetic Retinopathy Study Report #18 | Investigative Ophthalmology and Visual Science | 1998 | 300 |
| 44 | Phototransduction mechanism in retinal rods and cones. The Friedenwald Lecture | Investigative Ophthalmology and Visual Science | 1994 | 296 |
| 45 | Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632 | Investigative Ophthalmology and Visual Science | 2001 | 295 |
| 46 | VEGF is major stimulator in model of choroidal neovascularization | Investigative Ophthalmology and Visual Science | 2000 | 293 |
| 47 | Macular pigment and risk for age-related macular degeneration in subjects from a Northern European population | Investigative Ophthalmology and Visual Science | 2001 | 289 |
| 48 | Age-related accumulation and spatial distribution of lipofuscin in RPE of normal subjects | Investigative Ophthalmology and Visual Science | 2001 | 287 |
| 49 | A model of angiogenesis in the mouse cornea | Investigative Ophthalmology and Visual Science | 1996 | 286 |
| 50 | Myopic children show insufficient accommodative response to blur | Investigative Ophthalmology and Visual Science | 1993 | 283 |
