| # | Title | Journal | Year | Citations |
|---|
| 1 | Cisplatin in cancer therapy: Molecular mechanisms of action | European Journal of Pharmacology | 2014 | 3,667 |
| 2 | Behavioural despair in rats: A new model sensitive to antidepressant treatments | European Journal of Pharmacology | 1978 | 2,686 |
| 3 | The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review | European Journal of Pharmacology | 2003 | 2,382 |
| 4 | 6-hydroxy-dopamine induced degeneration of central monoamine neurons | European Journal of Pharmacology | 1968 | 1,995 |
| 5 | Intrathecal morphine in mice: A new technique | European Journal of Pharmacology | 1980 | 1,747 |
| 6 | Health effects of quercetin: From antioxidant to nutraceutical | European Journal of Pharmacology | 2008 | 1,487 |
| 7 | Central effects of stress hormones in health and disease: Understanding the protective and damaging effects of stress and stress mediators | European Journal of Pharmacology | 2008 | 1,364 |
| 8 | The mouse light/dark box test | European Journal of Pharmacology | 2003 | 1,037 |
| 9 | Receptor activity and turnover of dopamine and noradrenaline after neuroleptics | European Journal of Pharmacology | 1970 | 1,006 |
| 10 | Macrophage M1/M2 polarization | European Journal of Pharmacology | 2020 | 883 |
| 11 | Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase | European Journal of Pharmacology | 1987 | 848 |
| 12 | 8-Hydroxy-2-(di-n-propylamino)-tetralin discriminates between subtypes of the 5-HT1 recognition site | European Journal of Pharmacology | 1983 | 833 |
| 13 | Pharmacological profile of antidepressants and related compounds at human monoamine transporters | European Journal of Pharmacology | 1997 | 780 |
| 14 | Pathobiology of neuropathic pain | European Journal of Pharmacology | 2001 | 775 |
| 15 | Neuroendocrine pharmacology of stress | European Journal of Pharmacology | 2003 | 746 |
| 16 | Role of the bed nucleus of the stria terminalis versus the amygdala in fear, stress, and anxiety | European Journal of Pharmacology | 2003 | 736 |
| 17 | SCH 23390—The first selective dopamine D-1 antagonist | European Journal of Pharmacology | 1983 | 714 |
| 18 | Selective inhibition of the inducible nitric oxide synthase by aminoguanidine | European Journal of Pharmacology | 1993 | 676 |
| 19 | Catecholamine receptors on locus coeruleus neurons: Pharmacological characterization | European Journal of Pharmacology | 1977 | 674 |
| 20 | Quinolinic acid: A potent endogenous excitant at amino acid receptors in CNS | European Journal of Pharmacology | 1981 | 667 |
| 21 | Selective 60HDA-induced destruction of mesolimbic dopamine neurons: Abolition of psychostimulant-induced locomotor activity in rats | European Journal of Pharmacology | 1976 | 665 |
| 22 | Functional antagonists at the NMDA receptor complex exhibit antidepressant actions | European Journal of Pharmacology | 1990 | 662 |
| 23 | The involvement of subtypes of the 5-HT1 receptor and of catecholaminergic systems in the behavioural response to 8-hydroxy-2-(di-n-Propylamino) tetralin in the rat | European Journal of Pharmacology | 1984 | 650 |
| 24 | Nicotine preferentially stimulates dopamine release in the limbic system of freely moving rats | European Journal of Pharmacology | 1986 | 641 |
| 25 | A review of 25 years of the social interaction test | European Journal of Pharmacology | 2003 | 635 |
| 26 | Effect of antidepressant drugs on the depletion of intraneuronal brain 5-hydroxytryptamine stores caused by 4-methyl-α-ethyl-meta-tyramine | European Journal of Pharmacology | 1969 | 627 |
| 27 | The central effects of a novel dopamine agonist | European Journal of Pharmacology | 1978 | 627 |
| 28 | Molecular targeted therapy: Treating cancer with specificity | European Journal of Pharmacology | 2018 | 622 |
| 29 | Characterization of the selectivity, specificity and potency of medetomidine as an α2-adrenoceptor agonist | European Journal of Pharmacology | 1988 | 607 |
| 30 | Role of dopamine in the behavioural actions of nicotine related to addiction | European Journal of Pharmacology | 2000 | 600 |
| 31 | Cytokine-induced sickness behaviour: a neuroimmune response to activation of innate immunity | European Journal of Pharmacology | 2004 | 600 |
| 32 | Possible involvement of nitric oxide in long-term potentiation | European Journal of Pharmacology | 1991 | 588 |
| 33 | Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: A review of their intracellular targets | European Journal of Pharmacology | 2006 | 588 |
| 34 | Oxidant and antioxidant balance in the airways and airway diseases | European Journal of Pharmacology | 2006 | 583 |
| 35 | Co-existence of substance P and calcitonin gene-related peptide-like immunoreactivities in sensory nerves in relation to cardiovascular and bronchoconstrictor effects of capsaicin | European Journal of Pharmacology | 1985 | 562 |
| 36 | The binding of serotonergic ligands to the porcine choroid plexus: Characterization of a new type of serotonin recognition site | European Journal of Pharmacology | 1984 | 560 |
| 37 | Molecular pharmacology of 5-HT1 and 5-HT2 recognition sites in rat and pig brain membranes: Radioligand binding studies with [3H]5-HT, [3H]8-OH-DPAT, (−)[125I]iodocyanopindolol, [3H]mesulergine and [3H]Ketanserin | European Journal of Pharmacology | 1985 | 559 |
| 38 | Naltrindole, a highly selective and potent non-peptide δ opioid receptor antagonist | European Journal of Pharmacology | 1988 | 559 |
| 39 | “Behavioural despair” in rats and mice: Strain differences and the effects of imipramine | European Journal of Pharmacology | 1978 | 548 |
| 40 | Release of prostaglandins E and F in an algogenic reaction and its inhibition | European Journal of Pharmacology | 1980 | 542 |
| 41 | A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635 | European Journal of Pharmacology | 1995 | 537 |
| 42 | Effects of chemical stimulation of the mesolimbic dopamine system upon locomotor activity | European Journal of Pharmacology | 1976 | 533 |
| 43 | Immobility induced by forced swimming in rats: Effects of agents which modify central catecholamine and serotonin activity | European Journal of Pharmacology | 1979 | 531 |
| 44 | Excitotoxicity: Bridge to various triggers in neurodegenerative disorders | European Journal of Pharmacology | 2013 | 527 |
| 45 | Regulation of the expression of inducible nitric oxide synthase | European Journal of Pharmacology | 2004 | 517 |
| 46 | An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity | European Journal of Pharmacology | 1998 | 515 |
| 47 | Drug addiction as dopamine-dependent associative learning disorder | European Journal of Pharmacology | 1999 | 499 |
| 48 | Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in the rat in vivo | European Journal of Pharmacology | 1990 | 498 |
| 49 | Blockade by antidepressants and related compounds of biogenic amine uptake into rat brain synaptosomes: Most antidepressants selectively block norepinephrine uptake | European Journal of Pharmacology | 1984 | 496 |
| 50 | Analogues of β-LPH61–64 posessing selective agonist activity at μ-opiate receptors | European Journal of Pharmacology | 1981 | 488 |
