| # | Title | Journal | Year | Citations |
|---|
| 1 | Effectiveness and efficiency of guideline dissemination and implementation strategies | Health Technology Assessment | 2004 | 2,317 |
| 2 | Evaluating non-randomised intervention studies | Health Technology Assessment | 2003 | 1,983 |
| 3 | Clinical effectiveness and cost-effectiveness of elemental nutrition for the maintenance of remission in Crohn’s disease: a systematic review and meta-analysis | Health Technology Assessment | 2015 | 1,956 |
| 4 | Systematic review to identify and appraise outcome measures used to evaluate childhood obesity treatment interventions (CoOR): evidence of purpose, application, validity, reliability and sensitivity | Health Technology Assessment | 2014 | 1,553 |
| 5 | Consensus development methods, and their use in clinical guideline development. | Health Technology Assessment | 1998 | 1,052 |
| 6 | Acceptability, benefit and costs of early screening for hearing disability: a study of potential screening tests and models | Health Technology Assessment | 2007 | 1,026 |
| 7 | Virtual outreach: a randomised controlled trial and economic evaluation of joint teleconferenced medical consultations | Health Technology Assessment | 2004 | 1,016 |
| 8 | Evaluating patient-based outcome measures for use in clinical trials. | Health Technology Assessment | 1998 | 964 |
| 9 | Methods for evaluating area-wide and organisation-based interventions in health and health care: a systematic review. | Health Technology Assessment | 1999 | 962 |
| 10 | How important are comprehensive literature searches and the assessment of trial quality in systematic reviews? Empirical study | Health Technology Assessment | 2003 | 925 |
| 11 | How important are comprehensive literature searches and the assessment of trial quality in systematic reviews? Empirical study | Health Technology Assessment | 2003 | 919 |
| 12 | The clinical effectiveness and cost-effectiveness of bariatric (weight loss) surgery for obesity: a systematic review and economic evaluation | Health Technology Assessment | 2009 | 789 |
| 13 | The measurement of satisfaction with healthcare: implications for practice from a systematic review of the literature | Health Technology Assessment | 2002 | 768 |
| 14 | Dissemination and publication of research findings: an updated review of related biases | Health Technology Assessment | 2010 | 706 |
| 15 | The effectiveness of the Heidelberg Retina Tomograph and laser diagnostic glaucoma scanning system (GDx) in detecting and monitoring glaucoma | Health Technology Assessment | 2005 | 698 |
| 16 | Quality-of-life measures in chronic diseases of childhood | Health Technology Assessment | 2001 | 656 |
| 17 | Systematic reviews of trials and other studies | Health Technology Assessment | 1998 | 651 |
| 18 | Systematic review of the long-term effects and economic consequences of treatments for obesity and implications for health improvement | Health Technology Assessment | 2004 | 640 |
| 19 | A rapid and systematic review of the clinical effectiveness and cost-effectiveness of glycoprotein IIb/IIIa antagonists in the medical management of unstable angina | Health Technology Assessment | 2000 | 601 |
| 20 | Evaluation of the ventricular assist device programme in the UK | Health Technology Assessment | 2006 | 578 |
| 21 | Indirect comparisons of competing interventions | Health Technology Assessment | 2005 | 571 |
| 22 | Cetuximab for the first-line treatment of metastatic colorectal cancer | Health Technology Assessment | 2010 | 562 |
| 23 | Influence of reported study design characteristics on intervention effect estimates from randomised controlled trials: combined analysis of meta-epidemiological studies. | Health Technology Assessment | 2012 | 542 |
| 24 | Methods for the estimation of the National Institute for Health and Care Excellence cost-effectiveness threshold | Health Technology Assessment | 2015 | 536 |
| 25 | Lapatinib for the treatment of HER2-overexpressing breast cancer | Health Technology Assessment | 2009 | 522 |
| 26 | A systematic review of rapid diagnostic tests for the detection of tuberculosis infection | Health Technology Assessment | 2007 | 520 |
| 27 | Review of guidelines for good practice in decision-analytic modelling in health technology assessment | Health Technology Assessment | 2004 | 511 |
| 28 | Systematic review of treatments for atopic eczema. | Health Technology Assessment | 2000 | 503 |
| 29 | Design and use of questionnaires: a review of best practice applicable to surveys of health service staff and patients | Health Technology Assessment | 2001 | 500 |
| 30 | A rapid and systematic review of the evidence for the clinical effectiveness and cost-effectiveness of irinotecan, oxaliplatin and raltitrexed for the treatment of advanced colorectal cancer | Health Technology Assessment | 2001 | 498 |
| 31 | Early estimation of pandemic influenza Antiviral and Vaccine Effectiveness (EAVE): use of a unique community and laboratory national data-linked cohort study | Health Technology Assessment | 2015 | 488 |
| 32 | Qualitative research methods in health technology assessment: a review of the literature. | Health Technology Assessment | 1998 | 483 |
| 33 | Eliciting public preferences for healthcare: a systematic review of techniques | Health Technology Assessment | 2001 | 481 |
| 34 | Measurement of health-related quality of life for people with dementia: development of a new instrument (DEMQOL) and an evaluation of current methodology | Health Technology Assessment | 2005 | 463 |
| 35 | Behaviour change techniques: the development and evaluation of a taxonomic method for reporting and describing behaviour change interventions (a suite of five studies involving consensus methods, randomised controlled trials and analysis of qualitative data) | Health Technology Assessment | 2015 | 458 |
| 36 | Subgroup analyses in randomised controlled trials: quantifying the risks of false-positives and false-negatives | Health Technology Assessment | 2001 | 454 |
| 37 | The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients | Health Technology Assessment | 2013 | 447 |
| 38 | Types of urethral catheter for reducing symptomatic urinary tract infections in hospitalised adults requiring short-term catheterisation: multicentre randomised controlled trial and economic evaluation of antimicrobial- and antiseptic-impregnated urethral catheters (the CATHETER trial) | Health Technology Assessment | 2012 | 439 |
| 39 | Consensus development methods, and their use in clinical guideline development | Health Technology Assessment | 1998 | 428 |
| 40 | Improving the evaluation of therapeutic interventions in multiple sclerosis: the role of new psychometric methods | Health Technology Assessment | 2009 | 427 |
| 41 | Evaluating patient-based outcome measures for use in clinical trials | Health Technology Assessment | 1998 | 422 |
| 42 | Evaluating meta-ethnography: systematic analysis and synthesis of qualitative research | Health Technology Assessment | 2011 | 417 |
| 43 | Economic evaluation of a primary care-based education programme for patients with osteoarthritis of the knee | Health Technology Assessment | 1999 | 401 |
| 44 | SeHCAT [tauroselcholic (selenium-75) acid] for the investigation of bile acid malabsorption and measurement of bile acid pool loss: a systematic review and cost-effectiveness analysis | Health Technology Assessment | 2013 | 400 |
| 45 | Evaluation of diagnostic tests when there is no gold standard. A review of methods | Health Technology Assessment | 2007 | 395 |
| 46 | Methadone and buprenorphine for the management of opioid dependence: a systematic review and economic evaluation | Health Technology Assessment | 2007 | 390 |
| 47 | The inclusion of reports of randomised trials published in languages other than English in systematic reviews | Health Technology Assessment | 2003 | 380 |
| 48 | Systematic review and meta-analysis of the current evidence on the duration of protection by bacillus Calmette–Guérin vaccination against tuberculosis | Health Technology Assessment | 2013 | 366 |
| 49 | Prospective multicentre randomised, double-blind, equivalence study comparing clonidine and midazolam as intravenous sedative agents in critically ill children: the SLEEPS (Safety profiLe, Efficacy and Equivalence in Paediatric intensive care Sedation) study | Health Technology Assessment | 2014 | 366 |
| 50 | Systematic review and individual patient data meta-analysis of diagnosis of heart failure, with modelling of implications of different diagnostic strategies in primary care | Health Technology Assessment | 2009 | 365 |
