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Top Articles

#TitleJournalYearCitations
1TRAF molecules in cell signaling and in human diseasesJournal of Molecular Signaling2013362
2Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancerJournal of Molecular Signaling2010306
3Cell cycle arrest in Metformin treated breast cancer cells involves activation of AMPK, downregulation of cyclin D1, and requires p27<sup>Kip1</sup> or p21<sup>Cip1</sup>Journal of Molecular Signaling2008222
4Gadd45 in stress signalingJournal of Molecular Signaling2008185
5The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transitionJournal of Molecular Signaling2010177
6Molecular mechanisms mediating the G protein-coupled receptor regulation of cell cycle progressionJournal of Molecular Signaling2007123
7Combination of dasatinib and curcumin eliminates chemo-resistant colon cancer cellsJournal of Molecular Signaling2011122
8AMPK exerts dual regulatory effects on the PI3K pathwayJournal of Molecular Signaling2010114
9Curcumin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells: molecular mechanisms of apoptosis, migration and angiogenesisJournal of Molecular Signaling2007103
10Canonical Wnt signaling is involved in switching from cell proliferation to myogenic differentiation of mouse myoblast cellsJournal of Molecular Signaling201198
11NFAT5 in cellular adaptation to hypertonic stress – regulations and functional significanceJournal of Molecular Signaling201392
12Inhibition of PI3K/AKT and MEK/ERK pathways act synergistically to enhance antiangiogenic effects of EGCG through activation of FOXO transcription factorJournal of Molecular Signaling200886
13Sensitization of TRAIL-resistant LNCaP cells by resveratrol (3, 4', 5 tri-hydroxystilbene): molecular mechanisms and therapeutic potentialJournal of Molecular Signaling200783
14Multiple paxillin binding sites regulate FAK functionJournal of Molecular Signaling200879
15Enhanced catharanthine and vindoline production in suspension cultures of <em>Catharanthus roseus</em> by ultraviolet-B lightJournal of Molecular Signaling200879
16Multiple functions of G protein-coupled receptor kinasesJournal of Molecular Signaling201479
17EGFR/Met association regulates EGFR TKI resistance in breast cancerJournal of Molecular Signaling201078
18AMPK-induced activation of Akt by AICAR is mediated by IGF-1R dependent and independent mechanisms in acute lymphoblastic leukemiaJournal of Molecular Signaling201073
19Signaling in colon cancer stem cellsJournal of Molecular Signaling201268
20Zinc release from thapsigargin/IP3-sensitive stores in cultured cortical neuronsJournal of Molecular Signaling201060
21The adaptor protein p62/SQSTM1 in osteoclast signaling pathwaysJournal of Molecular Signaling201259
22Rac inhibits thrombin-induced Rho activation: evidence of a Pak-dependent GTPase crosstalkJournal of Molecular Signaling200657
23The roles played by highly truncated splice variants of G protein-coupled receptorsJournal of Molecular Signaling201255
24Abundance, complexation, and trafficking of Wnt/β-catenin signaling elements in response to Wnt3aJournal of Molecular Signaling200752
25Role of RGM coreceptors in bone morphogenetic protein signalingJournal of Molecular Signaling200747
26Estradiol effects on the dopamine transporter – protein levels, subcellular location, and functionJournal of Molecular Signaling200646
27Dual function of polycomb group proteins in differentiated murine T helper (CD4<sup>+</sup>) cellsJournal of Molecular Signaling201146
28Membrane TNF-alpha-activated programmed necrosis is mediated by Ceramide-induced reactive oxygen speciesJournal of Molecular Signaling201346
29Membrane estrogen receptor-α-mediated nongenomic actions of phytoestrogens in GH3/B6/F10 pituitary tumor cellsJournal of Molecular Signaling200944
30Src homology 2 (SH2) domain containing protein tyrosine phosphatase-1 (SHP-1) dephosphorylates VEGF Receptor-2 and attenuates endothelial DNA synthesis, but not migrationJournal of Molecular Signaling200843
31siRNA knockdown of GPR18 receptors in BV-2 microglia attenuates <em>N</em>-arachidonoyl glycine-induced cell migrationJournal of Molecular Signaling201243
32Ligand-dependent localization and intracellular stability of sigma-1 receptors in CHO-K1 ceJournal of Molecular Signaling200742
33Ovarian cancer G protein coupled receptor 1 suppresses cell migration of MCF7 breast cancer cells via a Gα<sub>12/13</sub>-Rho-Rac1 pathwayJournal of Molecular Signaling201341
34Chronic Inflammation in Skin MalignanciesJournal of Molecular Signaling201641
35Brain-derived neurotrophic factor receptor TrkB exists as a preformed dimer in living cellsJournal of Molecular Signaling201240
36Breast cancer cell invasion mediated by Gα12 signaling involves expression of interleukins-6 and −8, and matrix metalloproteinase-2Journal of Molecular Signaling201439
37SFRP-4 abrogates Wnt-3a-induced β-catenin and Akt/PKB signalling and reverses a Wnt-3a-imposed inhibition of <em>in vitro</em> mammary differentiationJournal of Molecular Signaling200837
38Clusterin expression can be modulated by changes in TCF1-mediated Wnt signalingJournal of Molecular Signaling200736
39The neurotransmitter dopamine modulates vascular permeability in the endotheliumJournal of Molecular Signaling200834
40Genetic and functional characterization of putative Ras/Raf interaction inhibitors in <em>C. elegans</em> and mammalian cellsJournal of Molecular Signaling201034
41Insights into the Shc Family of Adaptor ProteinsJournal of Molecular Signaling201734
42ArhGAP9, a novel MAP kinase docking protein, inhibits Erk and p38 activation through WW domain bindingJournal of Molecular Signaling200733
43Tumour promoting and suppressing roles of the atypical MAP kinase signalling pathway ERK3/4-MK5Journal of Molecular Signaling201232
44G-protein-coupled receptor-associated A-kinase anchoring proteins AKAP5 and AKAP12: differential signaling to MAPK and GPCR recyclingJournal of Molecular Signaling200830
45Glycogen Synthase Kinase-3beta regulates Snail and beta-catenin during gastrin-induced migration of gastric cancer cellsJournal of Molecular Signaling201030
46Neuronal aging: learning from <em>C. elegans</em>Journal of Molecular Signaling201330
47Caspase-3 mediated release of SAC domain containing fragment from Par-4 is necessary for the sphingosine-induced apoptosis in Jurkat cellsJournal of Molecular Signaling201329
48Wnt and Frizzled RNA expression in human mesenchymal and embryonic (H7) stem cellsJournal of Molecular Signaling200828
49Molecular targets and signaling pathways regulated by interleukin (IL)-24 in mediating its antitumor activitiesJournal of Molecular Signaling201327
50Defining regulatory and phosphoinositide-binding sites in the human WIPI-1 β-propeller responsible for autophagosomal membrane localization downstream of mTORC1 inhibitionJournal of Molecular Signaling201225