European Cytokine Network

2.7(top 20%)

impact factor

1.2K(top 20%)

papers

25.7K(top 10%)

citations

65(top 10%)

h-index

2.8(top 20%)

impact factor

1.2K

all documents

26.3K

doc citations

106(top 10%)

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Top Articles

#	Title	Journal	Year	Citations
1	Recent advances in the relationship between obesity, inflammation, and insulin resistance	European Cytokine Network	2006	1,415
2	Tumor necrosis factors: developments during the last decade	European Cytokine Network	1996	348
3	Three novel mammalian toll-like receptors: gene structure, expression, and evolution	European Cytokine Network	2000	313
4	Transforming growth factor-beta: a general review	European Cytokine Network	1996	306
5	IL-37: a new anti-inflammatory cytokine of the IL-1 family	European Cytokine Network	2011	302
6	VEGF-A: a critical regulator of blood vessel growth	European Cytokine Network	2009	281
7	Cloning and characterization of a sub-family of human toll-like receptors: hTLR7, hTLR8 and hTLR9	European Cytokine Network	2000	276
8	The biological properties of interleukin-1	European Cytokine Network	1994	227
9	Modulation of proinflammatory cytokine release in rheumatoid synovial membrane cell cultures. Comparison of monoclonal anti TNF-alpha antibody with the interleukin-1 receptor antagonist	European Cytokine Network	1995	208
10	Obesity and inflammation	European Cytokine Network	2018	191
11	Soluble intercellular adhesion molecule-1 (sICAM-1): an overview	European Cytokine Network	2004	175
12	IL-18 in autoimmunity: review	European Cytokine Network	2006	172
13	Interleukin-18, a proinflammatory cytokine	European Cytokine Network	2000	165
14	Neutrophil alpha-defensin human neutrophil peptide modulates cytokine production in human monocytes and adhesion molecule expression in endothelial cells	European Cytokine Network	2000	151
15	Spontaneous production of interleukin-10 by B lymphocytes and monocytes in systemic lupus erythematosus	European Cytokine Network	1993	142
16	Leptin and the immune system: how nutritional status influences the immune response	European Cytokine Network	2000	136
17	Apoptosis of endothelial cells. Contribution to the pathophysiology of atherosclerosis?	European Cytokine Network	1998	133
18	Pro- and anti-inflammatory responses are regulated simultaneously from the first moments of septic shock	European Cytokine Network	2011	131
19	Cytokines in Gaucher's disease	European Cytokine Network	1999	129
20	Toll-like receptor 4 Asp299Gly/Thr399Ile polymorphisms are a risk factor for Candida bloodstream infection	European Cytokine Network	2006	125
21	Inflammatory cells and chemokines sustain FGF2-induced angiogenesis	European Cytokine Network	2009	114
22	Innate defence functions of macrophages can be biased by nano-sized ceramic and metallic particles	European Cytokine Network	2004	113
23	Chemokines in proliferative diabetic retinopathy and proliferative vitreoretinopathy	European Cytokine Network	2006	113
24	Interleukin-18: biological properties and clinical implications	European Cytokine Network	2000	103
25	Cytokine profile in PFAPA syndrome suggests continuous inflammation and reduced anti-inflammatory response	European Cytokine Network	2006	102
26	Somatostatin and somatostatin receptors in the immune system: a review	European Cytokine Network	2000	100
27	TNF-induced microvascular pathology: active role for platelets and importance of the LFA-1/ICAM-1 interaction	European Cytokine Network	1993	97
28	Mechanisms of IL-33 processing and secretion: differences and similarities between IL-1 family members	European Cytokine Network	2012	95
29	TNFα mediates stress-induced depression by upregulating indoleamine 2,3-dioxygenase in a mouse model of unpredictable chronic mild stress	European Cytokine Network	2015	94
30	Cytokine single nucleotide polymorphisms in Iranian patients with pulmonary tuberculosis	European Cytokine Network	2006	89
31	Interleukin-1, tumor necrosis factor and their specific inhibitors	European Cytokine Network	1994	88
32	Biological activity and brain actions of recombinant rat interleukin-1alpha and interleukin-1beta	European Cytokine Network	1998	88
33	Interleukin-1 receptors	European Cytokine Network	1994	87
34	Extremely low frequency electromagnetic field and wound healing: implication of cytokines as biological mediators	European Cytokine Network	2013	86
35	Cytokines in the generation and maturation of dendritic cells: recent advances	European Cytokine Network	2002	86
36	Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8/SIGIRR	European Cytokine Network	2003	85
37	Stress-induced cytokine changes in rats	European Cytokine Network	2013	84
38	Hypoxia enhances CXCR4 expression in human microvascular endothelial cells and human melanoma cells	European Cytokine Network	2007	83
39	A rare allele combination of the interleukin-1 gene complex is associated with high interleukin-1 beta plasma levels in healthy individuals	European Cytokine Network	2000	83
40	Interleukin-6 is the central tumor growth factor in vitro and in vivo in multiple myeloma	European Cytokine Network	1990	82
41	Adenosine - cyclic AMP pathways and cytokine expression	European Cytokine Network	1999	82
42	Altered levels of pro-inflammatory cytokines in sickle cell disease patients during vaso-occlusive crises and the steady state condition	European Cytokine Network	2013	80
43	Effects of tumor necrosis factor-alpha and interleukin-6 in elderly populations	European Cytokine Network	2002	79
44	Cell surface glycoproteins expressed on activated human T cells induce production of interleukin-1 beta by monocytic cells: a possible role of CD69	European Cytokine Network	1993	78
45	The importance of shedding of membrane proteins for cytokine biology	European Cytokine Network	2000	78
46	TGF-β1 functional polymorphisms: a review	European Cytokine Network	2016	77
47	The interleukin-1 receptor complex and interleukin-1 signal transduction	European Cytokine Network	1997	77
48	The promoter polymorphism of the interleukin-6 gene regulates interleukin-6 production in neonates but not in adults	European Cytokine Network	2001	77
49	Anti-FGF2 approaches as a strategy to compensate resistance to anti-VEGF therapy: long-pentraxin 3 as a novel antiangiogenic FGF2-antagonist	European Cytokine Network	2009	76
50	Interleukin-6 and severe COVID-19: a systematic review and meta-analysis	European Cytokine Network	2020	76

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