| # | Title | Journal | Year | Citations |
|---|
| 1 | TGF-β and BMP signaling in osteoblast, skeletal development, and bone formation, homeostasis and disease | Bone Research | 2016 | 1,099 |
| 2 | Rheumatoid arthritis: pathological mechanisms and modern pharmacologic therapies | Bone Research | 2018 | 947 |
| 3 | Injectable hydrogels for cartilage and bone tissue engineering | Bone Research | 2017 | 840 |
| 4 | Osteoarthritis: toward a comprehensive understanding of pathological mechanism | Bone Research | 2017 | 731 |
| 5 | Bone Regeneration Based on Tissue Engineering Conceptions — A 21st Century Perspective | Bone Research | 2013 | 625 |
| 6 | Bone biomaterials and interactions with stem cells | Bone Research | 2017 | 503 |
| 7 | TGF-β/BMP signaling and other molecular events: regulation of osteoblastogenesis and bone formation | Bone Research | 2015 | 443 |
| 8 | Nanomaterials and bone regeneration | Bone Research | 2015 | 415 |
| 9 | Osteoclasts: New Insights | Bone Research | 2013 | 372 |
| 10 | Current research on pharmacologic and regenerative therapies for osteoarthritis | Bone Research | 2016 | 355 |
| 11 | Paracrine and endocrine actions of bone—the functions of secretory proteins from osteoblasts, osteocytes, and osteoclasts | Bone Research | 2018 | 339 |
| 12 | Long-term bone and lung consequences associated with hospital-acquired severe acute respiratory syndrome: a 15-year follow-up from a prospective cohort study | Bone Research | 2020 | 320 |
| 13 | Evolving concepts in bone infection: redefining “biofilm”, “acute vs. chronic osteomyelitis”, “the immune proteome” and “local antibiotic therapy” | Bone Research | 2019 | 300 |
| 14 | Calcium phosphate cements for bone engineering and their biological properties | Bone Research | 2017 | 277 |
| 15 | Bone tissue engineering via nanostructured calcium phosphate biomaterials and stem cells | Bone Research | 2014 | 274 |
| 16 | Transforming growth factor-β in stem cells and tissue homeostasis | Bone Research | 2018 | 262 |
| 17 | The Key Role of the Blood Supply to Bone | Bone Research | 2013 | 249 |
| 18 | Ankylosing spondylitis: etiology, pathogenesis, and treatments | Bone Research | 2019 | 229 |
| 19 | Vitamin D, calcium homeostasis and aging | Bone Research | 2016 | 228 |
| 20 | Molecular mechanosensors in osteocytes | Bone Research | 2020 | 209 |
| 21 | Advanced smart biomaterials and constructs for hard tissue engineering and regeneration | Bone Research | 2018 | 206 |
| 22 | mTOR signaling in skeletal development and disease | Bone Research | 2018 | 202 |
| 23 | Skeletal Blood Flow in Bone Repair and Maintenance | Bone Research | 2013 | 196 |
| 24 | Role of FGF/FGFR signaling in skeletal development and homeostasis: learning from mouse models | Bone Research | 2014 | 196 |
| 25 | Recent advances in nano scaffolds for bone repair | Bone Research | 2016 | 195 |
| 26 | YAP promotes osteogenesis and suppresses adipogenic differentiation by regulating β-catenin signaling | Bone Research | 2018 | 193 |
| 27 | Bone–cartilage crosstalk: a conversation for understanding osteoarthritis | Bone Research | 2016 | 191 |
| 28 | Subchondral bone microenvironment in osteoarthritis and pain | Bone Research | 2021 | 190 |
| 29 | TGF-β signaling and the development of osteoarthritis | Bone Research | 2014 | 184 |
| 30 | Painful intervertebral disc degeneration and inflammation: from laboratory evidence to clinical interventions | Bone Research | 2021 | 184 |
| 31 | Biomimetic delivery of signals for bone tissue engineering | Bone Research | 2018 | 178 |
| 32 | The art of building bone: emerging role of chondrocyte-to-osteoblast transdifferentiation in endochondral ossification | Bone Research | 2018 | 163 |
| 33 | Melatonin alleviates intervertebral disc degeneration by disrupting the IL-1β/NF-κB-NLRP3 inflammasome positive feedback loop | Bone Research | 2020 | 156 |
| 34 | Recent advances in smart stimuli-responsive biomaterials for bone therapeutics and regeneration | Bone Research | 2022 | 156 |
| 35 | Exosomes: roles and therapeutic potential in osteoarthritis | Bone Research | 2020 | 150 |
| 36 | Pathological mechanisms and therapeutic outlooks for arthrofibrosis | Bone Research | 2019 | 134 |
| 37 | Mechanical regulation of bone remodeling | Bone Research | 2022 | 134 |
| 38 | The fabrication of biomimetic biphasic CAN-PAC hydrogel with a seamless interfacial layer applied in osteochondral defect repair | Bone Research | 2017 | 127 |
| 39 | Exercise-induced irisin in bone and systemic irisin administration reveal new regulatory mechanisms of bone metabolism | Bone Research | 2017 | 126 |
| 40 | Autophagy in bone homeostasis and the onset of osteoporosis | Bone Research | 2019 | 125 |
| 41 | Review of a new bone tumor therapy strategy based on bifunctional biomaterials | Bone Research | 2021 | 125 |
| 42 | A review of UHMWPE wear-induced osteolysis: the role for early detection of the immune response | Bone Research | 2016 | 122 |
| 43 | Mechanically induced Ca2+ oscillations in osteocytes release extracellular vesicles and enhance bone formation | Bone Research | 2018 | 122 |
| 44 | Intestinal microbiota: a potential target for the treatment of postmenopausal osteoporosis | Bone Research | 2017 | 121 |
| 45 | Collagen type II suppresses articular chondrocyte hypertrophy and osteoarthritis progression by promoting integrin β1−SMAD1 interaction | Bone Research | 2019 | 121 |
| 46 | On the road to smart biomaterials for bone research: definitions, concepts, advances, and outlook | Bone Research | 2021 | 121 |
| 47 | Application of platelet-rich plasma with stem cells in bone and periodontal tissue engineering | Bone Research | 2016 | 114 |
| 48 | A Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice | Bone Research | 2013 | 109 |
| 49 | Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines | Bone Research | 2018 | 108 |
| 50 | RANKL signaling in bone marrow mesenchymal stem cells negatively regulates osteoblastic bone formation | Bone Research | 2018 | 104 |
