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Cancer & Metabolism
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top-articles
Cancer & Metabolism
5.0
(top 5%)
impact factor
322
(top 50%)
papers
9.7K
(top 20%)
citations
54
(top 10%)
h
-index
5.1
(top 5%)
impact factor
360
all documents
10.8K
doc citations
91
(top 10%)
g
-index
Top Articles
#
Title
Journal
Year
Citations
1
Mitochondrial reactive oxygen species and cancer
Cancer & Metabolism
2014
574
2
Metformin directly acts on mitochondria to alter cellular bioenergetics
Cancer & Metabolism
2014
330
3
Mitochondria as biosynthetic factories for cancer proliferation
Cancer & Metabolism
2015
308
4
Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration
Cancer & Metabolism
2017
284
5
Hypoxia signaling pathways in cancer metabolism: the importance of co-selecting interconnected physiological pathways
Cancer & Metabolism
2014
252
6
Defects in mitochondrial metabolism and cancer
Cancer & Metabolism
2014
208
7
Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth
Cancer & Metabolism
2013
207
8
Mitophagy and cancer
Cancer & Metabolism
2015
204
9
Balancing glycolytic flux: the role of 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatases in cancer metabolism
Cancer & Metabolism
2013
198
10
Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments
Cancer & Metabolism
2016
186
11
Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexia
Cancer & Metabolism
2014
182
12
Quantitative analysis of acetyl-CoA production in hypoxic cancer cells reveals substantial contribution from acetate
Cancer & Metabolism
2014
182
13
Metabolomics and metabolic pathway networks from human colorectal cancers, adjacent mucosa, and stool
Cancer & Metabolism
2016
177
14
Acidosis induces reprogramming of cellular metabolism to mitigate oxidative stress
Cancer & Metabolism
2013
169
15
Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells
Cancer & Metabolism
2013
163
16
The metabolic demands of cancer cells are coupled to their size and protein synthesis rates
Cancer & Metabolism
2013
142
17
Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth
Cancer & Metabolism
2015
139
18
Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism
Cancer & Metabolism
2014
137
19
A strategically designed small molecule attacks alpha-ketoglutarate dehydrogenase in tumor cells through a redox process
Cancer & Metabolism
2014
133
20
Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities
Cancer & Metabolism
2017
133
21
PGC-1α supports glutamine metabolism in breast cancer
Cancer & Metabolism
2013
130
22
The rate of glycolysis quantitatively mediates specific histone acetylation sites
Cancer & Metabolism
2015
121
23
Metabolic and transcriptional profiling reveals pyruvate dehydrogenase kinase 4 as a mediator of epithelial-mesenchymal transition and drug resistance in tumor cells
Cancer & Metabolism
2014
119
24
Warburg effect(s)—a biographical sketch of Otto Warburg and his impacts on tumor metabolism
Cancer & Metabolism
2016
117
25
GLUT3 is induced during epithelial-mesenchymal transition and promotes tumor cell proliferation in non-small cell lung cancer
Cancer & Metabolism
2014
115
26
Bortezomib resistance in multiple myeloma is associated with increased serine synthesis
Cancer & Metabolism
2017
115
27
Separation of metabolic supply and demand: aerobic glycolysis as a normal physiological response to fluctuating energetic demands in the membrane
Cancer & Metabolism
2014
110
28
Treatment of glioma patients with ketogenic diets: report of two cases treated with an IRB-approved energy-restricted ketogenic diet protocol and review of the literature
Cancer & Metabolism
2015
110
29
Calorie restriction and cancer prevention: a mechanistic perspective
Cancer & Metabolism
2013
109
30
The diversity and breadth of cancer cell fatty acid metabolism
Cancer & Metabolism
2021
107
31
Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone
Cancer & Metabolism
2015
104
32
Metabolic requirements for cancer cell proliferation
Cancer & Metabolism
2016
99
33
Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma
Cancer & Metabolism
2013
96
34
Inhibition of 6-phosphofructo-2-kinase (PFKFB3) induces autophagy as a survival mechanism
Cancer & Metabolism
2014
96
35
TIGAR, TIGAR, burning bright
Cancer & Metabolism
2014
92
36
Endothelial cell metabolism: parallels and divergences with cancer cell metabolism
Cancer & Metabolism
2014
91
37
Integration of omics: more than the sum of its parts
Cancer & Metabolism
2016
91
38
Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells
Cancer & Metabolism
2013
87
39
The α-ketoglutarate dehydrogenase complex in cancer metabolic plasticity
Cancer & Metabolism
2017
78
40
Fructose contributes to the Warburg effect for cancer growth
Cancer & Metabolism
2020
76
41
Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells
Cancer & Metabolism
2013
75
42
Activated lymphocytes as a metabolic model for carcinogenesis
Cancer & Metabolism
2013
72
43
Epithelial-mesenchymal transition induction is associated with augmented glucose uptake and lactate production in pancreatic ductal adenocarcinoma
Cancer & Metabolism
2016
72
44
DHODH and cancer: promising prospects to be explored
Cancer & Metabolism
2021
71
45
Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302
Cancer & Metabolism
2015
69
46
Glutaminase-1 (GLS1) inhibition limits metastatic progression in osteosarcoma
Cancer & Metabolism
2020
69
47
Linking vitamin B1 with cancer cell metabolism
Cancer & Metabolism
2013
68
48
Novel drugs that target the metabolic reprogramming in renal cell cancer
Cancer & Metabolism
2016
64
49
p53 promotes the expression of gluconeogenesis-related genes and enhances hepatic glucose production
Cancer & Metabolism
2013
63
50
SIRT3 and SIRT4 are mitochondrial tumor suppressor proteins that connect mitochondrial metabolism and carcinogenesis
Cancer & Metabolism
2014
63
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