| # | Title | Journal | Year | Citations |
|---|
| 1 | SARS-CoV-2 and COVID-19 in older adults: what we may expect regarding pathogenesis, immune responses, and outcomes | GeroScience | 2020 | 404 |
| 2 | A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup | GeroScience | 2018 | 221 |
| 3 | Sarcopenia during COVID-19 lockdown restrictions: long-term health effects of short-term muscle loss | GeroScience | 2020 | 218 |
| 4 | The impact of aging on cardiac extracellular matrix | GeroScience | 2017 | 168 |
| 5 | Neuroprotective mechanisms of astaxanthin: a potential therapeutic role in preserving cognitive function in age and neurodegeneration | GeroScience | 2017 | 138 |
| 6 | Geroscience and the trans-NIH Geroscience Interest Group, GSIG | GeroScience | 2017 | 131 |
| 7 | A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs | GeroScience | 2017 | 125 |
| 8 | Severe COVID-19 and aging: are monocytes the key? | GeroScience | 2020 | 118 |
| 9 | The effect of social distance measures on COVID-19 epidemics in Europe: an interrupted time series analysis | GeroScience | 2020 | 117 |
| 10 | A frailty index from common clinical and laboratory tests predicts increased risk of death across the life course | GeroScience | 2017 | 115 |
| 11 | COVID-19-associated cardiovascular morbidity in older adults: a position paper from the Italian Society of Cardiovascular Researches | GeroScience | 2020 | 115 |
| 12 | Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation | GeroScience | 2018 | 114 |
| 13 | Topical rapamycin reduces markers of senescence and aging in human skin: an exploratory, prospective, randomized trial | GeroScience | 2019 | 114 |
| 14 | Effect of rapamycin on aging and age-related diseases—past and future | GeroScience | 2021 | 114 |
| 15 | IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan | GeroScience | 2017 | 111 |
| 16 | Lipoteichoic acid from the cell wall of a heat killed Lactobacillus paracasei D3-5 ameliorates aging-related leaky gut, inflammation and improves physical and cognitive functions: from C. elegans to mice | GeroScience | 2020 | 111 |
| 17 | Apigenin suppresses the senescence-associated secretory phenotype and paracrine effects on breast cancer cells | GeroScience | 2017 | 106 |
| 18 | How healthy is the healthspan concept? | GeroScience | 2018 | 106 |
| 19 | Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain | GeroScience | 2020 | 102 |
| 20 | The frailty index outperforms DNA methylation age and its derivatives as an indicator of biological age | GeroScience | 2017 | 100 |
| 21 | Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment | GeroScience | 2019 | 97 |
| 22 | Increase in blood–brain barrier leakage in healthy, older adults | GeroScience | 2020 | 96 |
| 23 | Short-term time-restricted feeding is safe and feasible in non-obese healthy midlife and older adults | GeroScience | 2020 | 91 |
| 24 | Microglia activation and phagocytosis: relationship with aging and cognitive impairment in the rhesus monkey | GeroScience | 2017 | 90 |
| 25 | Gastro-intestinal and oral microbiome signatures associated with healthy aging | GeroScience | 2019 | 89 |
| 26 | Sulforaphane - role in aging and neurodegeneration | GeroScience | 2019 | 89 |
| 27 | Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects | GeroScience | 2020 | 85 |
| 28 | The gut microbiome–derived metabolite trimethylamine N-oxide modulates neuroinflammation and cognitive function with aging | GeroScience | 2021 | 85 |
| 29 | Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging | GeroScience | 2019 | 84 |
| 30 | Regulation of senescence traits by MAPKs | GeroScience | 2020 | 84 |
| 31 | Discovery and ranking of the most robust prognostic biomarkers in serous ovarian cancer | GeroScience | 2023 | 82 |
| 32 | The potential role of necroptosis in inflammaging and aging | GeroScience | 2019 | 81 |
| 33 | Nrf2 dysfunction and impaired cellular resilience to oxidative stressors in the aged vasculature: from increased cellular senescence to the pathogenesis of age-related vascular diseases | GeroScience | 2019 | 80 |
| 34 | A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse | GeroScience | 2017 | 79 |
| 35 | Extracellular vesicles from mesenchymal stem cells reduce microglial-mediated neuroinflammation after cortical injury in aged Rhesus monkeys | GeroScience | 2020 | 79 |
| 36 | Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence | GeroScience | 2017 | 78 |
| 37 | Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer’s disease | GeroScience | 2017 | 78 |
| 38 | One-year Mediterranean diet promotes epigenetic rejuvenation with country- and sex-specific effects: a pilot study from the NU-AGE project | GeroScience | 2020 | 76 |
| 39 | Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects | GeroScience | 2019 | 75 |
| 40 | Efficacy of curcumin for age-associated cognitive decline: a narrative review of preclinical and clinical studies | GeroScience | 2018 | 73 |
| 41 | Novel coronavirus epidemic in the Hungarian population, a cross-sectional nationwide survey to support the exit policy in Hungary | GeroScience | 2020 | 73 |
| 42 | Cognitive status, fast walking speed and walking speed reserve—the Gait and Alzheimer Interactions Tracking (GAIT) study | GeroScience | 2017 | 71 |
| 43 | Demonstration of impaired neurovascular coupling responses in TG2576 mouse model of Alzheimer’s disease using functional laser speckle contrast imaging | GeroScience | 2017 | 70 |
| 44 | Association of inflammatory mediators with frailty status in older adults: results from a systematic review and meta-analysis | GeroScience | 2020 | 70 |
| 45 | CMV immune evasion and manipulation of the immune system with aging | GeroScience | 2017 | 69 |
| 46 | Monkeypox: considerations for the understanding and containment of the current outbreak in non-endemic countries | GeroScience | 2022 | 69 |
| 47 | The GH/IGF-1 axis in a critical period early in life determines cellular DNA repair capacity by altering transcriptional regulation of DNA repair-related genes: implications for the developmental origins of cancer | GeroScience | 2017 | 65 |
| 48 | Retinal biomarkers for Alzheimer’s disease and vascular cognitive impairment and dementia (VCID): implication for early diagnosis and prognosis | GeroScience | 2020 | 64 |
| 49 | Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment | GeroScience | 2017 | 63 |
| 50 | Composition and richness of the serum microbiome differ by age and link to systemic inflammation | GeroScience | 2018 | 63 |
