6.6(top 5%)
impact factor
425(top 50%)
papers
16.7K(top 10%)
citations
63(top 10%)
h-index
6.7(top 5%)
impact factor
568
all documents
18.4K
doc citations
104(top 10%)
g-index

Top Articles

#TitleJournalYearCitations
1Signaling via the NFκB systemWiley Interdisciplinary Reviews: Systems Biology and Medicine2016724
2Hematopoietic stem cell: self‐renewal versus differentiationWiley Interdisciplinary Reviews: Systems Biology and Medicine2010666
3Oxygen homeostasisWiley Interdisciplinary Reviews: Systems Biology and Medicine2010288
4Post‐translational modification: nature's escape from genetic imprisonment and the basis for dynamic information encodingWiley Interdisciplinary Reviews: Systems Biology and Medicine2012288
5The mammalian phenotype ontology: enabling robust annotation and comparative analysisWiley Interdisciplinary Reviews: Systems Biology and Medicine2009267
6Skeletal muscle: A review of molecular structure and function, in health and diseaseWiley Interdisciplinary Reviews: Systems Biology and Medicine2020262
7Hybrid models of tumor growthWiley Interdisciplinary Reviews: Systems Biology and Medicine2011256
8In silico methods for drug repurposing and pharmacologyWiley Interdisciplinary Reviews: Systems Biology and Medicine2016250
9Agent‐based models in translational systems biologyWiley Interdisciplinary Reviews: Systems Biology and Medicine2009247
10Promise of personalized omics to precision medicineWiley Interdisciplinary Reviews: Systems Biology and Medicine2013245
11Systems biology and the future of medicineWiley Interdisciplinary Reviews: Systems Biology and Medicine2011239
12Cell mechanics: principles, practices, and prospectsWiley Interdisciplinary Reviews: Systems Biology and Medicine2014232
13PharmGKB: A worldwide resource for pharmacogenomic informationWiley Interdisciplinary Reviews: Systems Biology and Medicine2018205
14Role of neutrophils in innate immunity: a systems biology‐level approachWiley Interdisciplinary Reviews: Systems Biology and Medicine2009203
15A systems biology approach to synovial joint lubrication in health, injury, and diseaseWiley Interdisciplinary Reviews: Systems Biology and Medicine2012191
16Cancer and inflammationWiley Interdisciplinary Reviews: Systems Biology and Medicine2017166
17Adaptation of cells to new environmentsWiley Interdisciplinary Reviews: Systems Biology and Medicine2011148
18DNA methylation and gene expressionWiley Interdisciplinary Reviews: Systems Biology and Medicine2010138
19Sox2 and Oct‐3/4: a versatile pair of master regulators that orchestrate the self‐renewal and pluripotency of embryonic stem cellsWiley Interdisciplinary Reviews: Systems Biology and Medicine2009136
20Influenza A virus infection kinetics: quantitative data and modelsWiley Interdisciplinary Reviews: Systems Biology and Medicine2011136
21Vascular tissue engineering: from in vitro to in situWiley Interdisciplinary Reviews: Systems Biology and Medicine2014135
22Mechano‐sensing and transduction by endothelial surface glycocalyx: composition, structure, and functionWiley Interdisciplinary Reviews: Systems Biology and Medicine2013132
23Molecular networks in Network Medicine: Development and applicationsWiley Interdisciplinary Reviews: Systems Biology and Medicine2020128
24Mesenchymal stem cell differentiation and roles in regenerative medicineWiley Interdisciplinary Reviews: Systems Biology and Medicine2009126
25Boolean modeling: a logic‐based dynamic approach for understanding signaling and regulatory networks and for making useful predictionsWiley Interdisciplinary Reviews: Systems Biology and Medicine2014122
26The application of flux balance analysis in systems biologyWiley Interdisciplinary Reviews: Systems Biology and Medicine2010116
27Genome‐scale metabolic networksWiley Interdisciplinary Reviews: Systems Biology and Medicine2009115
28Central dopaminergic circuitry controlling food intake and reward: implications for the regulation of obesityWiley Interdisciplinary Reviews: Systems Biology and Medicine2010115
29Image‐based models of cardiac structure in health and diseaseWiley Interdisciplinary Reviews: Systems Biology and Medicine2010113
30In silico models of cancerWiley Interdisciplinary Reviews: Systems Biology and Medicine2010103
31Multiscale modeling for biologistsWiley Interdisciplinary Reviews: Systems Biology and Medicine2009102
32Nutritional regulation of division of labor in honey bees: toward a systems biology perspectiveWiley Interdisciplinary Reviews: Systems Biology and Medicine2010100
33APOBEC‐1‐mediated RNA editingWiley Interdisciplinary Reviews: Systems Biology and Medicine2010100
34Drug repurposing and adverse event prediction using high‐throughput literature analysisWiley Interdisciplinary Reviews: Systems Biology and Medicine2011100
35Gastrointestinal systemWiley Interdisciplinary Reviews: Systems Biology and Medicine201099
36Role of systems pharmacology in understanding drug adverse eventsWiley Interdisciplinary Reviews: Systems Biology and Medicine201199
37Systematic analysis of posttranscriptional gene expressionWiley Interdisciplinary Reviews: Systems Biology and Medicine201098
38Reprogramming cells and tissue patterning via bioelectrical pathways: molecular mechanisms and biomedical opportunitiesWiley Interdisciplinary Reviews: Systems Biology and Medicine201397
39Rule‐based modeling: a computational approach for studying biomolecular site dynamics in cell signaling systemsWiley Interdisciplinary Reviews: Systems Biology and Medicine201497
40Mechanisms controlling hematopoietic stem cell functions during normal hematopoiesis and hematological malignanciesWiley Interdisciplinary Reviews: Systems Biology and Medicine201196
41Immunity to CRISPR Cas9 and Cas12a therapeuticsWiley Interdisciplinary Reviews: Systems Biology and Medicine201896
42Adenosine‐to‐inosine RNA editingWiley Interdisciplinary Reviews: Systems Biology and Medicine200995
43Metabolic network modeling of microbial communitiesWiley Interdisciplinary Reviews: Systems Biology and Medicine201595
44The virtual liver: a multidisciplinary, multilevel challenge for systems biologyWiley Interdisciplinary Reviews: Systems Biology and Medicine201293
45Hydrogels for in vivo‐like three‐dimensional cellular studiesWiley Interdisciplinary Reviews: Systems Biology and Medicine201292
46Blood type biochemistry and human diseaseWiley Interdisciplinary Reviews: Systems Biology and Medicine201692
47Systems approaches and algorithms for discovery of combinatorial therapiesWiley Interdisciplinary Reviews: Systems Biology and Medicine201091
48Ischemic kidney injury and mechanisms of tissue repairWiley Interdisciplinary Reviews: Systems Biology and Medicine201188
49Genome‐wide DNA methylation profilingWiley Interdisciplinary Reviews: Systems Biology and Medicine201085
50MicroRNAs in cardiomyocyte developmentWiley Interdisciplinary Reviews: Systems Biology and Medicine201184