Drug Discovery Today: Disease Models

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#	Title	Journal	Year	Citations
1	Models of chronic kidney disease	Drug Discovery Today: Disease Models	2010	232
2	A neurobiological model of insomnia	Drug Discovery Today: Disease Models	2011	128
3	The symptom cluster of sleep, fatigue and depressive symptoms in breast cancer patients: severity of the problem and treatment options	Drug Discovery Today: Disease Models	2011	124
4	On habits and addiction: an associative analysis of compulsive drug seeking	Drug Discovery Today: Disease Models	2008	114
5	Hedonic homeostatic dysregulation as a driver of drug-seeking behavior	Drug Discovery Today: Disease Models	2008	95
6	Mouse models for Type 1 Diabetes	Drug Discovery Today: Disease Models	2009	83
7	Animal models of depression	Drug Discovery Today: Disease Models	2006	81
8	Models of dengue virus infection	Drug Discovery Today: Disease Models	2006	74
9	Relapse to drug seeking following prolonged abstinence: the role of environmental stimuli	Drug Discovery Today: Disease Models	2008	72
10	Models of reactive oxygen species in cancer	Drug Discovery Today: Disease Models	2007	63
11	Cellular and network mechanisms of electrographic seizures	Drug Discovery Today: Disease Models	2008	60
12	Regeneration and functional recovery following peripheral nerve injury	Drug Discovery Today: Disease Models	2004	59
13	Zebrafish heart regeneration as a model for cardiac tissue repair	Drug Discovery Today: Disease Models	2007	53
14	Sheep as a model species for the study and treatment of human asthma and other respiratory diseases	Drug Discovery Today: Disease Models	2009	51
15	Protease activity and the role of the endothelial glycocalyx in inflammation	Drug Discovery Today: Disease Models	2011	51
16	Mathematical modeling and synthetic biology	Drug Discovery Today: Disease Models	2008	48
17	Mast cell proteases and inflammation	Drug Discovery Today: Disease Models	2011	47
18	Experimental models of membranous nephropathy	Drug Discovery Today: Disease Models	2010	46
19	Fish: a suitable system to model human bone disorders and discover drugs with osteogenic or osteotoxic activities	Drug Discovery Today: Disease Models	2014	46
20	Stress and rodent models of drug addiction: role of VTA–accumbens–PFC–amygdala circuit	Drug Discovery Today: Disease Models	2008	45
21	Viral infections and multiple sclerosis	Drug Discovery Today: Disease Models	2020	44
22	Diet-induced models for obesity and type 2 diabetes	Drug Discovery Today: Disease Models	2007	43
23	Mouse models of lipodystrophy: Key reagents for the understanding of the metabolic syndrome	Drug Discovery Today: Disease Models	2007	42
24	Fish in a dish: drug discovery for hearing habilitation	Drug Discovery Today: Disease Models	2013	42
25	Reward comparison: the Achilles’ heel and hope for addiction	Drug Discovery Today: Disease Models	2008	38
26	Simulation models for in silico testing of closed-loop glucose controllers in type 1 diabetes	Drug Discovery Today: Disease Models	2008	38
27	The nematode Caenorhabditis elegans as a model for aging research	Drug Discovery Today: Disease Models	2018	38
28	Zebrafish as a model for cardiovascular development and disease	Drug Discovery Today: Disease Models	2008	35
29	Models of epithelial–mesenchymal transition	Drug Discovery Today: Disease Models	2005	32
30	Drosophila melanogaster as a model system for the genetics of postnatal cardiac function	Drug Discovery Today: Disease Models	2008	31
31	ADMETox in zebrafish	Drug Discovery Today: Disease Models	2013	31
32	Systems pharmacology of hepatic metabolism in zebrafish larvae	Drug Discovery Today: Disease Models	2016	31
33	Models of gender differences in cardiovascular disease	Drug Discovery Today: Disease Models	2007	30
34	Models of HIV-1 disease: A review of current status	Drug Discovery Today: Disease Models	2006	29
35	Rodent models for autism: A critical review	Drug Discovery Today: Disease Models	2005	28
36	Rabbit models of heart disease	Drug Discovery Today: Disease Models	2008	28
37	A review of mathematical models for leukemia and lymphoma	Drug Discovery Today: Disease Models	2015	28
38	Modeling CNS microglia: the quest to identify predictive models	Drug Discovery Today: Disease Models	2008	27
39	Animal models of autoimmune and immune-mediated uveitis	Drug Discovery Today: Disease Models	2006	26
40	In silico modeling of interstitial lung mechanics: implications for disease development and repair	Drug Discovery Today: Disease Models	2007	26
41	Epstein-Barr virus infection in the development of neurological disorders	Drug Discovery Today: Disease Models	2020	26
42	Wildlife-microbiome interactions and disease: exploring opportunities for disease mitigation across ecological scales	Drug Discovery Today: Disease Models	2018	25
43	Chediak-Higashi syndrome: A review of the past, present, and future	Drug Discovery Today: Disease Models	2020	25
44	Animal models for infectious diseases caused by parasites: Leishmaniasis	Drug Discovery Today: Disease Models	2004	24
45	Models of ovarian cancer metastasis: Murine models	Drug Discovery Today: Disease Models	2006	24
46	Models of pulmonary fibrosis	Drug Discovery Today: Disease Models	2006	24
47	Animal models of regression/progression of kidney disease	Drug Discovery Today: Disease Models	2014	24
48	Development of animal models of human IgA nephropathy	Drug Discovery Today: Disease Models	2014	24
49	Genetically modified mouse models of cancer invasion and metastasis	Drug Discovery Today: Disease Models	2011	23
50	Animal models for heart valve research and development	Drug Discovery Today: Disease Models	2017	23

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