# | Title | Journal | Year | Citations |
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1 | Luteolin, a Flavonoid with Potential for Cancer Prevention and Therapy | Current Cancer Drug Targets | 2008 | 855 |
2 | The Role of Snail in EMT and Tumorigenesis | Current Cancer Drug Targets | 2013 | 688 |
3 | The PTEN/PI3K/AKT Signalling Pathway in Cancer, Therapeutic Implications | Current Cancer Drug Targets | 2008 | 685 |
4 | Bortezomib as the First Proteasome Inhibitor Anticancer Drug: Current Status and Future Perspectives | Current Cancer Drug Targets | 2011 | 671 |
5 | P-glycoprotein Inhibition as a Therapeutic Approach for Overcoming Multidrug Resistance in Cancer: Current Status and Future Perspectives | Current Cancer Drug Targets | 2013 | 320 |
6 | Taxanes: Microtubule and Centrosome Targets, and Cell Cycle Dependent Mechanisms of Action | Current Cancer Drug Targets | 2003 | 318 |
7 | Garlic [Allium sativum]: A Review of its Potential Use as an Anti-Cancer Agent | Current Cancer Drug Targets | 2003 | 308 |
8 | The Role of Fibroblast Growth Factors in Tumor Growth | Current Cancer Drug Targets | 2009 | 305 |
9 | Paclitaxel Resistance: Molecular Mechanisms and Pharmacologic Manipulation | Current Cancer Drug Targets | 2003 | 302 |
10 | MDM2 is a Central Node in the p53 Pathway: 12 Years and Counting | Current Cancer Drug Targets | 2005 | 285 |
11 | The Urokinase Plasminogen Activator System: A Target for Anti-Cancer Therapy | Current Cancer Drug Targets | 2009 | 265 |
12 | Matrix Metalloproteinases as Therapeutic Targets in Cancer | Current Cancer Drug Targets | 2005 | 253 |
13 | Oxidative Stress and Cancer: The Role of Nrf2 | Current Cancer Drug Targets | 2018 | 250 |
14 | How Do Microtubule-Targeted Drugs Work? An Overview | Current Cancer Drug Targets | 2007 | 245 |
15 | Targeted Therapy for Advanced Prostate Cancer: Inhibition of the PI3K/Akt/mTOR Pathway | Current Cancer Drug Targets | 2009 | 244 |
16 | Sulfonamides and Sulfonylated Derivatives as Anticancer Agents | Current Cancer Drug Targets | 2002 | 243 |
17 | Structure and Functional Relationships of Hsp90 | Current Cancer Drug Targets | 2003 | 242 |
18 | Clinical Trials with Oncolytic Adenovirus in China | Current Cancer Drug Targets | 2007 | 240 |
19 | The Akt Pathway: Molecular Targets for Anti-Cancer Drug Development | Current Cancer Drug Targets | 2004 | 240 |
20 | Cytokines, Inflammation and Colon Cancer | Current Cancer Drug Targets | 2011 | 239 |
21 | Ribonucleotide Reductase Inhibitors and Future Drug Design | Current Cancer Drug Targets | 2006 | 237 |
22 | Apoptosis is a Critical Cellular Event in Cancer Chemoprevention and Chemotherapy by Selenium Compounds | Current Cancer Drug Targets | 2004 | 236 |
23 | Induction of Apoptosis by Curcumin and Its Implications for Cancer Therapy | Current Cancer Drug Targets | 2005 | 236 |
24 | MDM2 and Human Malignancies: Expression, Clinical Pathology, Prognostic Markers, and Implications for Chemotherapy | Current Cancer Drug Targets | 2005 | 227 |
25 | Overview of Proteasome Inhibitor-Based Anti-cancer Therapies: Perspective on Bortezomib and Second Generation Proteasome Inhibitors versus Future Generation Inhibitors of Ubiquitin-Proteasome System | Current Cancer Drug Targets | 2014 | 224 |
26 | MicroRNA Key to Angiogenesis Regulation: MiRNA Biology and Therapy | Current Cancer Drug Targets | 2018 | 221 |
27 | Oxygen-independent Regulation of HIF-1: Novel Involvement of PI3K/ AKT/mTOR Pathway in Cancer | Current Cancer Drug Targets | 2013 | 220 |
28 | Clinical Development of 17-Allylamino, 17-Demethoxygeldanamycin | Current Cancer Drug Targets | 2003 | 218 |
29 | Wnt / β-Catenin Signaling Pathway as Novel Cancer Drug Targets | Current Cancer Drug Targets | 2004 | 218 |
30 | Epithelial Mesenchymal Transition and Cancer Stem Cell-Like Phenotypes Facilitate Chemoresistance in Recurrent Ovarian Cancer | Current Cancer Drug Targets | 2010 | 201 |
31 | Cancer Therapy with ß-Lapachone | Current Cancer Drug Targets | 2002 | 200 |
32 | Marizomib, a Proteasome Inhibitor for All Seasons: Preclinical Profile and a Framework for Clinical Trials | Current Cancer Drug Targets | 2011 | 200 |
33 | NSAIDs and Chemoprevention | Current Cancer Drug Targets | 2004 | 199 |
34 | Deregulation of the Akt Pathway in Human Cancer | Current Cancer Drug Targets | 2008 | 199 |
35 | Targeting EGFR for Treatment of Glioblastoma: Molecular Basis to Overcome Resistance | Current Cancer Drug Targets | 2012 | 196 |
36 | Anti-Angiogenic and Anti-Inflammatory Effects of Statins: Relevance to Anti-Cancer Therapy | Current Cancer Drug Targets | 2005 | 190 |
37 | Mechanisms Used by Human Papillomaviruses to Escape the Host Immune Response | Current Cancer Drug Targets | 2007 | 187 |
38 | The Stress Response: Implications for the Clinical Development of Hsp90 Inhibitors | Current Cancer Drug Targets | 2003 | 186 |
39 | NOTCH Signaling as a Novel Cancer Therapeutic Target | Current Cancer Drug Targets | 2006 | 185 |
40 | Oncorine, the World First Oncolytic Virus Medicine and its Update in China | Current Cancer Drug Targets | 2018 | 178 |
41 | Ultraviolet B Regulation of Transcription Factor Families: Roles of Nuclear Factor-kappa B (NF-κB) and Activator Protein-1 (AP-1) in UVB-Induced Skin Carcinogenesis | Current Cancer Drug Targets | 2007 | 169 |
42 | Protein Kinase C Isozymes as Potential Targets for Anticancer Therapy | Current Cancer Drug Targets | 2004 | 169 |
43 | Crosstalk Between Epidermal Growth Factor Receptor- and Insulin-Like Growth Factor-1 Receptor Signaling: Implications for Cancer Therapy | Current Cancer Drug Targets | 2009 | 165 |
44 | AKT Signaling in Regulating Angiogenesis | Current Cancer Drug Targets | 2008 | 163 |
45 | Microfilament Actin Remodeling as a Potential Target for Cancer Drug Development | Current Cancer Drug Targets | 2004 | 162 |
46 | Targeting Apoptosis Pathways in Cancer Therapy | Current Cancer Drug Targets | 2004 | 158 |
47 | Signal Transducers and Activators of Transcription (STATs): Novel Targets of Chemopreventive and Chemotherapeutic Drugs | Current Cancer Drug Targets | 2006 | 158 |
48 | Overcoming Drug Resistance by Enhancing Apoptosis of Tumor Cells | Current Cancer Drug Targets | 2009 | 157 |
49 | Anti-Apoptotic Mechanisms of Drug Resistance in Cancer | Current Cancer Drug Targets | 2009 | 157 |
50 | Cellular FLICE-Like Inhibitory Protein (C-FLIP): A Novel Target for Cancer Therapy | Current Cancer Drug Targets | 2008 | 156 |