# | Title | Journal | Year | Citations |
---|
1 | PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65 | Open Biology | 2012 | 725 |
2 | Progress and prospects of early detection in lung cancer | Open Biology | 2017 | 552 |
3 | Wound healing: cellular mechanisms and pathological outcomes | Open Biology | 2020 | 546 |
4 | Targeting BCL-2 regulated apoptosis in cancer | Open Biology | 2018 | 377 |
5 | T-cell epitope vaccine design by immunoinformatics | Open Biology | 2013 | 324 |
6 | Oxidants, antioxidants and the current incurability of metastatic cancers | Open Biology | 2013 | 303 |
7 | Neuron–glia crosstalk in health and disease: fractalkine and CX3CR1 take centre stage | Open Biology | 2013 | 279 |
8 | The role of astrocytes in amyloid production and Alzheimer's disease | Open Biology | 2017 | 269 |
9 | Recent advances in dynamic m 6 A RNA modification | Open Biology | 2016 | 265 |
10 | Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines | Open Biology | 2020 | 232 |
11 | Structured illumination of the interface between centriole and peri-centriolar material | Open Biology | 2012 | 225 |
12 | Heterotrimeric G protein signalling in the plant kingdom | Open Biology | 2013 | 218 |
13 | Sphingolipids: membrane microdomains in brain development, function and neurological diseases | Open Biology | 2017 | 215 |
14 | High-throughput recombinant protein expression in Escherichia coli : current status and future perspectives | Open Biology | 2016 | 211 |
15 | Atomic force microscopy-based microrheology reveals significant differences in the viscoelastic response between malign and benign cell lines | Open Biology | 2014 | 202 |
16 | A toolkit enabling efficient, scalable and reproducible gene tagging in trypanosomatids | Open Biology | 2015 | 202 |
17 | Neutrophil heterogeneity in health and disease: a revitalized avenue in inflammation and immunity | Open Biology | 2012 | 199 |
18 | Mate and fuse: how yeast cells do it | Open Biology | 2013 | 199 |
19 | The ANGPTL3-4-8 model, a molecular mechanism for triglyceride trafficking | Open Biology | 2016 | 179 |
20 | Temporal development of the infant gut microbiome | Open Biology | 2019 | 172 |
21 | Cancer drug pan-resistance: pumps, cancer stem cells, quiescence, epithelial to mesenchymal transition, blocked cell death pathways, persisters or what? | Open Biology | 2012 | 169 |
22 | Regulation of gene expression in trypanosomatids: living with polycistronic transcription | Open Biology | 2019 | 166 |
23 | How the extracellular matrix shapes neural development | Open Biology | 2019 | 166 |
24 | Biosynthesis and biology of mammalian GPI-anchored proteins | Open Biology | 2020 | 166 |
25 | Ultrasensitive response motifs: basic amplifiers in molecular signalling networks | Open Biology | 2013 | 165 |
26 | Drosophilaas a model system to unravel the layers of innate immunity to infection | Open Biology | 2012 | 162 |
27 | L-form bacteria, cell walls and the origins of life | Open Biology | 2013 | 162 |
28 | Cancer immunotherapy: broadening the scope of targetable tumours | Open Biology | 2018 | 162 |
29 | Bacterial genospecies that are not ecologically coherent: population genomics ofRhizobium leguminosarum | Open Biology | 2015 | 160 |
30 | SNPs in microRNA target sites and their potential role in human disease | Open Biology | 2017 | 157 |
31 | Structural insights into the functional diversity of the CDK–cyclin family | Open Biology | 2018 | 156 |
32 | Control of mitochondrial biogenesis and function by the ubiquitin–proteasome system | Open Biology | 2017 | 152 |
33 | Predicting virus emergence amid evolutionary noise | Open Biology | 2017 | 149 |
34 | Protein SUMOylation modification and its associations with disease | Open Biology | 2017 | 148 |
35 | A genome-wide resource of cell cycle and cell shape genes of fission yeast | Open Biology | 2013 | 147 |
36 | Quantitative single-molecule microscopy reveals that CENP-A Cnp1 deposition occurs during G2 in fission yeast | Open Biology | 2012 | 145 |
37 | Transcriptomic identification of starfish neuropeptide precursors yields new insights into neuropeptide evolution | Open Biology | 2016 | 144 |
38 | Structure and evolutionary history of a large family of NLR proteins in the zebrafish | Open Biology | 2016 | 143 |
39 | Towards an evolutionary theory of the origin of life based on kinetics and thermodynamics | Open Biology | 2013 | 141 |
40 | Lignin biosynthesis: old roads revisited and new roads explored | Open Biology | 2019 | 136 |
41 | TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells | Open Biology | 2012 | 135 |
42 | Visualizing the complex functions and mechanisms of the anaphase promoting complex/cyclosome (APC/C) | Open Biology | 2017 | 133 |
43 | The distinct fate of smooth and roughMycobacterium abscessusvariants inside macrophages | Open Biology | 2016 | 132 |
44 | Over-expression of Plk4 induces centrosome amplification, loss of primary cilia and associated tissue hyperplasia in the mouse | Open Biology | 2015 | 130 |
45 | Anti-cancer peptides: classification, mechanism of action, reconstruction and modification | Open Biology | 2020 | 127 |
46 | Region-specific RNA m 6 A methylation represents a new layer of control in the gene regulatory network in the mouse brain | Open Biology | 2017 | 126 |
47 | lncRNAs in development and disease: from functions to mechanisms | Open Biology | 2017 | 126 |
48 | Synaptic dysfunction in neurodegenerative and neurodevelopmental diseases: an overview of induced pluripotent stem-cell-based disease models | Open Biology | 2018 | 126 |
49 | Assessment of viral community functional potential from viral metagenomes may be hampered by contamination with cellular sequences | Open Biology | 2013 | 123 |
50 | MethylRAD: a simple and scalable method for genome-wide DNA methylation profiling using methylation-dependent restriction enzymes | Open Biology | 2015 | 123 |