6.9(top 5%)
impact factor
1.2K(top 20%)
papers
36.6K(top 10%)
citations
84(top 10%)
h-index
7.1(top 5%)
impact factor
1.5K
all documents
42.3K
doc citations
129(top 10%)
g-index

Top Articles

#TitleJournalYearCitations
1Targeting Metabolism for Cancer TherapyCell Chemical Biology2017677
2Lessons in PROTAC Design from Selective Degradation with a Promiscuous WarheadCell Chemical Biology2018556
3Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell StateCell Chemical Biology2019556
4Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and MacrophagesCell Chemical Biology2017424
5The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case StudyCell Chemical Biology2018422
6Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma ModelCell Chemical Biology2019399
7Autophagy-Dependent Ferroptosis: Machinery and RegulationCell Chemical Biology2020399
8Tumor Organoids as a Pre-clinical Cancer Model for Drug DiscoveryCell Chemical Biology2017388
9A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase DegraderCell Chemical Biology2018313
10Targeted Protein Degradation: from Chemical Biology to Drug DiscoveryCell Chemical Biology2017286
11N-Acetyl Cysteine Functions as a Fast-Acting Antioxidant by Triggering Intracellular H2S and Sulfane Sulfur ProductionCell Chemical Biology2018270
12Carbon Sources Tune Antibiotic Susceptibility in Pseudomonas aeruginosa via Tricarboxylic Acid Cycle ControlCell Chemical Biology2017264
13Whole-body and Whole-Organ Clearing and Imaging Techniques with Single-Cell Resolution: Toward Organism-Level Systems Biology in MammalsCell Chemical Biology2016263
14The Emerging Role of RNA as a Therapeutic Target for Small MoleculesCell Chemical Biology2016249
15Hedgehog Signaling: From Basic Biology to Cancer TherapyCell Chemical Biology2017242
16PROTACs: An Emerging Therapeutic Modality in Precision MedicineCell Chemical Biology2020242
17New Insights into the Biosynthetic Logic of Ribosomally Synthesized and Post-translationally Modified Peptide Natural ProductsCell Chemical Biology2016241
18Nucleic Acid Modifications in Regulation of Gene ExpressionCell Chemical Biology2016219
19High-Throughput Plasma Lipidomics: Detailed Mapping of the Associations with Cardiometabolic Risk FactorsCell Chemical Biology2019219
20Cell-Line Selectivity Improves the Predictive Power of Pharmacogenomic Analyses and Helps Identify NADPH as Biomarker for Ferroptosis SensitivityCell Chemical Biology2016217
21Breakdown of an Ironclad Defense System: The Critical Role of NRF2 in Mediating FerroptosisCell Chemical Biology2020215
22The Chemistry and Biology of FerroptosisCell Chemical Biology2020204
23A Bright Future for Precision Medicine: Advances in Fluorescent Chemical Probe Design and Their Clinical ApplicationCell Chemical Biology2016200
24Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of Cellular ATP on Target EngagementCell Chemical Biology2018197
25Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AMLCell Chemical Biology2019188
26RNA-DNA Triplex Formation by Long Noncoding RNAsCell Chemical Biology2016183
27Exploring Targeted Degradation Strategy for Oncogenic KRASG12CCell Chemical Biology2020182
28Repurposing High-Throughput Image Assays Enables Biological Activity Prediction for Drug DiscoveryCell Chemical Biology2018176
29Regulation of Virulence in Staphylococcus aureus : Molecular Mechanisms and Remaining PuzzlesCell Chemical Biology2016166
30Protein Lipidation in Cell Signaling and Diseases: Function, Regulation, and Therapeutic OpportunitiesCell Chemical Biology2018160
31The Rheumatoid Arthritis-Associated CitrullinomeCell Chemical Biology2018158
32Symbiont-Derived Antimicrobials Contribute to the Control of the Lepidopteran Gut MicrobiotaCell Chemical Biology2017157
33Unmasking Fucosylation: from Cell Adhesion to Immune System Regulation and DiseasesCell Chemical Biology2018156
34A Data-Driven Approach to Predicting Successes and Failures of Clinical TrialsCell Chemical Biology2016154
35Inhibition of Dpp8/9 Activates the Nlrp1b InflammasomeCell Chemical Biology2018154
36Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical ActivityCell Chemical Biology2019151
37Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7Cell Chemical Biology2017149
38Specific Knockdown of Endogenous Tau Protein by Peptide-Directed Ubiquitin-Proteasome DegradationCell Chemical Biology2016147
39Fungal Cordycepin Biosynthesis Is Coupled with the Production of the Safeguard Molecule PentostatinCell Chemical Biology2017145
40Achieving Life through Death: Redox Biology of Lipid Peroxidation in FerroptosisCell Chemical Biology2020144
41APOBEC Enzymes as Targets for Virus and Cancer TherapyCell Chemical Biology2018137
42Ferroptosis and Necroptosis in the KidneyCell Chemical Biology2020137
43Bile Acid 7α-Dehydroxylating Gut Bacteria Secrete Antibiotics that Inhibit Clostridium difficile: Role of Secondary Bile AcidsCell Chemical Biology2019134
44EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 ComplexCell Chemical Biology2020131
45Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD⋅Yap Protein-Protein InteractionCell Chemical Biology2019129
46Iron Biochemistry is Correlated with Amyloid Plaque Morphology in an Established Mouse Model of Alzheimer's DiseaseCell Chemical Biology2017128
47MemBright: A Family of Fluorescent Membrane Probes for Advanced Cellular Imaging and NeuroscienceCell Chemical Biology2019128
48DNA Charge Transport: from Chemical Principles to the CellCell Chemical Biology2016127
49Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical DegraderCell Chemical Biology2020127
50Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target InteractionsCell Chemical Biology2018124