| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the Design and Statistical Analysis of Experiments Using Laboratory Animals | ILAR Journal | 2002 | 679 |
| 2 | The 1996 Guide for the Care and Use of Laboratory Animals | ILAR Journal | 1997 | 466 |
| 3 | Sample Size Determination | ILAR Journal | 2002 | 458 |
| 4 | Monoclonal Versus Polyclonal Antibodies: Distinguishing Characteristics, Applications, and Information Resources | ILAR Journal | 2005 | 423 |
| 5 | Assessing Spatial Learning and Memory in Rodents | ILAR Journal | 2014 | 405 |
| 6 | Mechanisms of Cryoinjury in Living Cells | ILAR Journal | 2000 | 378 |
| 7 | Fish Sedation, Anesthesia, Analgesia, and Euthanasia: Considerations, Methods, and Types of Drugs | ILAR Journal | 2009 | 336 |
| 8 | Animal Models of Focal and Global Cerebral Ischemia | ILAR Journal | 2003 | 312 |
| 9 | Adjuvants and Antibody Production: Dispelling the Myths Associated with Freund's Complete and Other Adjuvants | ILAR Journal | 2005 | 312 |
| 10 | Zucker Diabetic Fatty Rat as a Model for Non-insulin-dependent Diabetes Mellitus | ILAR Journal | 1990 | 265 |
| 11 | Anesthesia and Euthanasia in Zebrafish | ILAR Journal | 2012 | 248 |
| 12 | Stereotypies and Other Abnormal Repetitive Behaviors: Potential Impact on Validity, Reliability, and Replicability of Scientific Outcomes | ILAR Journal | 2005 | 245 |
| 13 | Design and Statistical Methods in Studies Using Animal Models of Development | ILAR Journal | 2006 | 241 |
| 14 | Use of Positron Emission Tomography in Animal Research | ILAR Journal | 2001 | 230 |
| 15 | Small Fish Models for Identifying and Assessing the Effects of Endocrine-disrupting Chemicals | ILAR Journal | 2004 | 217 |
| 16 | Diseases of Amphibians | ILAR Journal | 2007 | 209 |
| 17 | Social Defeat as an Animal Model for Depression | ILAR Journal | 2014 | 209 |
| 18 | The Marmoset as a Model of Aging and Age-Related Diseases | ILAR Journal | 2011 | 206 |
| 19 | Tick-Borne Zoonoses in the United States: Persistent and Emerging Threats to Human Health | ILAR Journal | 2017 | 203 |
| 20 | Urinary Bladder Cancer in Dogs, a Naturally Occurring Model for Cancer Biology and Drug Development | ILAR Journal | 2014 | 202 |
| 21 | Environmental Epigenetics and Its Implication on Disease Risk and Health Outcomes | ILAR Journal | 2012 | 201 |
| 22 | Mice Anesthesia, Analgesia, and Care, Part I: Anesthetic Considerations in Preclinical Research | ILAR Journal | 2012 | 193 |
| 23 | Anesthesia and Other Considerations for in Vivo Imaging of Small Animals | ILAR Journal | 2008 | 191 |
| 24 | Environmental Enrichment for Laboratory Rodents and Rabbits: Requirements of Rodents, Rabbits, and Research | ILAR Journal | 2005 | 187 |
| 25 | Animal Models of Huntington's Disease | ILAR Journal | 2007 | 185 |
| 26 | Establishing an Appropriate Period of Acclimatization Following Transportation of Laboratory Animals | ILAR Journal | 2006 | 183 |
| 27 | The Collaborative Cross: A Recombinant Inbred Mouse Population for the Systems Genetic Era | ILAR Journal | 2011 | 183 |
| 28 | Communication of Adult Rats by Ultrasonic Vocalization: Biological, Sociobiological, and Neuroscience Approaches | ILAR Journal | 2009 | 179 |
| 29 | Canine Osteosarcoma: A Naturally Occurring Disease to Inform Pediatric Oncology | ILAR Journal | 2014 | 176 |
| 30 | Methicillin-Resistant Staphylococcus aureus in Animals | ILAR Journal | 2010 | 174 |
| 31 | Mouse Models of Diabetic Neuropathy | ILAR Journal | 2014 | 173 |
| 32 | The Altered Schaedler Flora: Continued Applications of a Defined Murine Microbial Community | ILAR Journal | 2015 | 173 |
| 33 | Are RNA Viruses Candidate Agents for the Next Global Pandemic? A Review | ILAR Journal | 2017 | 171 |
| 34 | Porcine Models of Cutaneous Wound Healing | ILAR Journal | 2015 | 170 |
| 35 | Amphibians as Models for Studying Environmental Change | ILAR Journal | 2007 | 169 |
| 36 | Successful Aging and Sustained Good Health in the Naked Mole Rat: A Long-Lived Mammalian Model for Biogerontology and Biomedical Research | ILAR Journal | 2011 | 169 |
| 37 | Inflammatory Models of Pain and Hyperalgesia | ILAR Journal | 1999 | 168 |
| 38 | Macaque Models of Human Infectious Disease | ILAR Journal | 2008 | 165 |
| 39 | Use of the Gottingen Minipig as a Model of Diabetes, with Special Focus on Type 1 Diabetes Research | ILAR Journal | 2004 | 161 |
| 40 | Rat Models of Type 1 Diabetes: Genetics, Environment, and Autoimmunity | ILAR Journal | 2004 | 160 |
| 41 | Critical Steps in the Production of Polyclonal and Monoclonal Antibodies: Evaluation and Recommendations | ILAR Journal | 2005 | 160 |
| 42 | Nonhuman Primate Models of Parkinson's Disease | ILAR Journal | 2007 | 158 |
| 43 | The Significance of Meaning: Why Do Over 90% of Behavioral Neuroscience Results Fail to Translate to Humans, and What Can We Do to Fix It? | ILAR Journal | 2014 | 156 |
| 44 | Analyses of Intestinal Microbiota: Culture versus Sequencing: Figure 1 | ILAR Journal | 2015 | 156 |
| 45 | Trapping and Marking Terrestrial Mammals for Research: Integrating Ethics, Performance Criteria, Techniques, and Common Sense | ILAR Journal | 2003 | 153 |
| 46 | Biological Effects of Blood Loss: Implications for Sampling Volumes and Techniques * Commentary: H. Richard Adams | ILAR Journal | 1989 | 152 |
| 47 | Animal Models of Myopia: Learning How Vision Controls the Size of the Eye | ILAR Journal | 1999 | 152 |
| 48 | Animal Models That Elucidate Basic Principles of the Developmental Origins of Adult Diseases | ILAR Journal | 2006 | 152 |
| 49 | The Intestinal Microbiota in Inflammatory Bowel Disease | ILAR Journal | 2015 | 152 |
| 50 | Old World Nonhuman Primate Models of Type 2 Diabetes Mellitus | ILAR Journal | 2006 | 151 |
