Molecular Neurodegeneration

12.9(top 1%)

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1.3K(top 20%)

papers

64.2K(top 5%)

citations

120(top 5%)

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13.1(top 1%)

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1.3K

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71.9K

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184(top 5%)

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Top Articles

#	Title	Journal	Year	Citations
1	The neuropathological diagnosis of Alzheimer’s disease	Molecular Neurodegeneration	2019	1,497
2	Adult hippocampal neurogenesis and its role in Alzheimer's disease	Molecular Neurodegeneration	2011	820
3	Exosomal cell-to-cell transmission of alpha synuclein oligomers	Molecular Neurodegeneration	2012	708
4	Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers	Molecular Neurodegeneration	2007	655
5	The SH-SY5Y cell line in Parkinson’s disease research: a systematic review	Molecular Neurodegeneration	2017	636
6	Does neuroinflammation fan the flame in neurodegenerative diseases?	Molecular Neurodegeneration	2009	595
7	Mitochondria dysfunction in the pathogenesis of Alzheimer’s disease: recent advances	Molecular Neurodegeneration	2020	562
8	The release and trans-synaptic transmission of Tau via exosomes	Molecular Neurodegeneration	2017	475
9	Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice	Molecular Neurodegeneration	2011	462
10	Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer’s disease	Molecular Neurodegeneration	2020	438
11	Pathophysiology, treatment, and animal and cellular models of human ischemic stroke	Molecular Neurodegeneration	2011	431
12	Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s disease	Molecular Neurodegeneration	2014	424
13	Late onset Alzheimer’s disease genetics implicates microglial pathways in disease risk	Molecular Neurodegeneration	2017	407
14	Alzheimer's disease: synaptic dysfunction and Aβ	Molecular Neurodegeneration	2009	388
15	The Alzheimer's disease Beta-secretase enzyme, BACE1	Molecular Neurodegeneration	2007	386
16	The role of tau in neurodegeneration	Molecular Neurodegeneration	2009	353
17	The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer’s disease	Molecular Neurodegeneration	2016	349
18	MicroRNA-7 targets Nod-like receptor protein 3 inflammasome to modulate neuroinflammation in the pathogenesis of Parkinson’s disease	Molecular Neurodegeneration	2016	347
19	TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson’s disease	Molecular Neurodegeneration	2013	323
20	Deletion of aquaporin-4 in APP/PS1 mice exacerbates brain Aβ accumulation and memory deficits	Molecular Neurodegeneration	2015	322
21	The amyloid precursor protein: beyond amyloid	Molecular Neurodegeneration	2006	316
22	α-Synuclein and neuronal cell death	Molecular Neurodegeneration	2009	314
23	NADPH oxidase in brain injury and neurodegenerative disorders	Molecular Neurodegeneration	2017	314
24	Practical considerations for choosing a mouse model of Alzheimer’s disease	Molecular Neurodegeneration	2017	305
25	New insights into the role of TREM2 in Alzheimer’s disease	Molecular Neurodegeneration	2018	286
26	Glial contributions to neurodegeneration in tauopathies	Molecular Neurodegeneration	2017	283
27	Neuron loss in the 5XFAD mouse model of Alzheimer’s disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activation	Molecular Neurodegeneration	2013	278
28	Pericyte-specific expression of PDGF beta receptor in mouse models with normal and deficient PDGF beta receptor signaling	Molecular Neurodegeneration	2010	274
29	Regulated protein aggregation: stress granules and neurodegeneration	Molecular Neurodegeneration	2012	271
30	Genetics of amyotrophic lateral sclerosis: an update	Molecular Neurodegeneration	2013	271
31	TREM2 in Neurodegenerative Diseases	Molecular Neurodegeneration	2017	270
32	Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease	Molecular Neurodegeneration	2018	267
33	PINK1 and Parkin mitochondrial quality control: a source of regional vulnerability in Parkinson’s disease	Molecular Neurodegeneration	2020	264
34	Alpha-synuclein structure and Parkinson’s disease – lessons and emerging principles	Molecular Neurodegeneration	2019	262
35	Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer’s disease	Molecular Neurodegeneration	2018	260
36	Calcium signaling in neurodegeneration	Molecular Neurodegeneration	2009	258
37	Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2	Molecular Neurodegeneration	2014	257
38	Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology	Molecular Neurodegeneration	2019	253
39	Alzheimer's disease: synapses gone cold	Molecular Neurodegeneration	2011	250
40	Diet and exercise orthogonally alter the gut microbiome and reveal independent associations with anxiety and cognition	Molecular Neurodegeneration	2014	250
41	Development and validation of a simplified method to generate human microglia from pluripotent stem cells	Molecular Neurodegeneration	2018	250
42	Biology and pathophysiology of the amyloid precursor protein	Molecular Neurodegeneration	2011	249
43	HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?	Molecular Neurodegeneration	2013	240
44	Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease	Molecular Neurodegeneration	2016	236
45	Tau exon 10 alternative splicing and tauopathies	Molecular Neurodegeneration	2008	225
46	Blood–brain-barriers in aging and in Alzheimer’s disease	Molecular Neurodegeneration	2013	222
47	Models of β-amyloid induced Tau-pathology: the long and “folded” road to understand the mechanism	Molecular Neurodegeneration	2014	220
48	Tau PET imaging: present and future directions	Molecular Neurodegeneration	2017	220
49	Alpha-synuclein and tau: teammates in neurodegeneration?	Molecular Neurodegeneration	2014	216
50	SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer’s disease	Molecular Neurodegeneration	2014	216

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