# | Title | Journal | Year | Citations |
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1 | The role and mechanisms of action of microRNAs in cancer drug resistance | Clinical Epigenetics | 2019 | 468 |
2 | Statistical predictions with glmnet | Clinical Epigenetics | 2019 | 460 |
3 | Epigenetic age acceleration predicts cancer, cardiovascular, and all-cause mortality in a German case cohort | Clinical Epigenetics | 2016 | 434 |
4 | Circulating microRNAs as potential cancer biomarkers: the advantage and disadvantage | Clinical Epigenetics | 2018 | 389 |
5 | Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors | Clinical Epigenetics | 2012 | 388 |
6 | Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy | Clinical Epigenetics | 2010 | 357 |
7 | Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy | Clinical Epigenetics | 2016 | 333 |
8 | DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies | Clinical Epigenetics | 2015 | 330 |
9 | The epigenetic effects of butyrate: potential therapeutic implications for clinical practice | Clinical Epigenetics | 2012 | 303 |
10 | Sirtuin functions and modulation: from chemistry to the clinic | Clinical Epigenetics | 2016 | 291 |
11 | The timeline of epigenetic drug discovery: from reality to dreams | Clinical Epigenetics | 2019 | 275 |
12 | Frailty is associated with the epigenetic clock but not with telomere length in a German cohort | Clinical Epigenetics | 2016 | 250 |
13 | Differences in smoking associated DNA methylation patterns in South Asians and Europeans | Clinical Epigenetics | 2014 | 246 |
14 | Influences of diet and the gut microbiome on epigenetic modulation in cancer and other diseases | Clinical Epigenetics | 2015 | 229 |
15 | Epigenetic targets of bioactive dietary components for cancer prevention and therapy | Clinical Epigenetics | 2010 | 210 |
16 | Air pollution and DNA methylation: effects of exposure in humans | Clinical Epigenetics | 2019 | 202 |
17 | The emerging role of epigenetics in human autoimmune disorders | Clinical Epigenetics | 2019 | 200 |
18 | The epigenetic clock as a predictor of disease and mortality risk: a systematic review and meta-analysis | Clinical Epigenetics | 2019 | 198 |
19 | Epigenetic treatment of solid tumours: a review of clinical trials | Clinical Epigenetics | 2015 | 183 |
20 | Epigenetic therapy for ovarian cancer: promise and progress | Clinical Epigenetics | 2019 | 181 |
21 | Histone acetyltransferases: challenges in targeting bi-substrate enzymes | Clinical Epigenetics | 2016 | 180 |
22 | Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells | Clinical Epigenetics | 2011 | 177 |
23 | Pharmacokinetic and pharmacodynamic analysis of 5-aza-2’-deoxycytidine (decitabine) in the design of its dose-schedule for cancer therapy | Clinical Epigenetics | 2013 | 177 |
24 | Imprinting disorders: a group of congenital disorders with overlapping patterns of molecular changes affecting imprinted loci | Clinical Epigenetics | 2015 | 174 |
25 | Epigenetics and male reproduction: the consequences of paternal lifestyle on fertility, embryo development, and children lifetime health | Clinical Epigenetics | 2015 | 168 |
26 | Changes in DNA methylation at the aryl hydrocarbon receptor repressor may be a new biomarker for smoking | Clinical Epigenetics | 2013 | 167 |
27 | Environmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidence | Clinical Epigenetics | 2015 | 166 |
28 | Recent developments on the role of epigenetics in obesity and metabolic disease | Clinical Epigenetics | 2015 | 162 |
29 | Specific or not specific recruitment of DNMTs for DNA methylation, an epigenetic dilemma | Clinical Epigenetics | 2018 | 160 |
30 | DNA methylation: conducting the orchestra from exposure to phenotype? | Clinical Epigenetics | 2016 | 157 |
31 | MicroRNA-mediated drug resistance in breast cancer | Clinical Epigenetics | 2011 | 156 |
32 | From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition? | Clinical Epigenetics | 2015 | 156 |
33 | Obesity-related DNA methylation at imprinted genes in human sperm: Results from the TIEGER study | Clinical Epigenetics | 2016 | 151 |
34 | Epigenetics in cancer therapy and nanomedicine | Clinical Epigenetics | 2019 | 147 |
35 | Differential DNA methylation of genes involved in fibrosis progression in non-alcoholic fatty liver disease and alcoholic liver disease | Clinical Epigenetics | 2015 | 145 |
36 | Epigenetic activities of flavonoids in the prevention and treatment of cancer | Clinical Epigenetics | 2015 | 144 |
37 | Hypermethylation of the TGF-β target, ABCA1 is associated with poor prognosis in ovarian cancer patients | Clinical Epigenetics | 2015 | 133 |
38 | Platelet mitochondrial DNA methylation: a potential new marker of cardiovascular disease | Clinical Epigenetics | 2015 | 132 |
39 | A clinical-molecular update on azanucleoside-based therapy for the treatment of hematologic cancers | Clinical Epigenetics | 2016 | 129 |
40 | Maternal intake of methyl-group donors affects DNA methylation of metabolic genes in infants | Clinical Epigenetics | 2017 | 129 |
41 | Aberrant DNA methylation in melanoma: biomarker and therapeutic opportunities | Clinical Epigenetics | 2017 | 129 |
42 | Obesity accelerates epigenetic aging in middle-aged but not in elderly individuals | Clinical Epigenetics | 2017 | 128 |
43 | Long interspersed nuclear element-1 hypomethylation in cancer: biology and clinical applications | Clinical Epigenetics | 2011 | 122 |
44 | cPAS-based sequencing on the BGISEQ-500 to explore small non-coding RNAs | Clinical Epigenetics | 2016 | 122 |
45 | Blood-based DNA methylation as biomarker for breast cancer: a systematic review | Clinical Epigenetics | 2016 | 121 |
46 | Promoter de-methylation of cyclin D2 by sulforaphane in prostate cancer cells | Clinical Epigenetics | 2011 | 120 |
47 | Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy | Clinical Epigenetics | 2017 | 118 |
48 | Air pollution-induced placental alterations: an interplay of oxidative stress, epigenetics, and the aging phenotype? | Clinical Epigenetics | 2019 | 118 |
49 | Epigenetic alterations following early postnatal stress: a review on novel aetiological mechanisms of common psychiatric disorders | Clinical Epigenetics | 2015 | 117 |
50 | Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci | Clinical Epigenetics | 2019 | 116 |