# | Title | Journal | Year | Citations |
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1 | Carbonic anhydrase inhibitors | Medicinal Research Reviews | 2003 | 1,126 |
2 | Flavonoids: Promising anticancer agents | Medicinal Research Reviews | 2003 | 928 |
3 | Click chemistry reactions in medicinal chemistry: Applications of the 1,3‐dipolar cycloaddition between azides and alkynes | Medicinal Research Reviews | 2008 | 885 |
4 | Antioxidant and other biological activities of phenols from olives and olive oil | Medicinal Research Reviews | 2002 | 635 |
5 | Small Molecule Modulators of Keap1‐Nrf2‐ARE Pathway as Potential Preventive and Therapeutic Agents | Medicinal Research Reviews | 2012 | 633 |
6 | Combining docking and molecular dynamic simulations in drug design | Medicinal Research Reviews | 2006 | 586 |
7 | Comprehensive Review in Current Developments of Imidazole-Based Medicinal Chemistry | Medicinal Research Reviews | 2014 | 575 |
8 | Copper in diseases and treatments, and copper‐based anticancer strategies | Medicinal Research Reviews | 2010 | 568 |
9 | The Keap1–Nrf2–ARE Pathway As a Potential Preventive and Therapeutic Target: An Update | Medicinal Research Reviews | 2016 | 562 |
10 | Cyclopentenone prostaglandins: New insights on biological activities and cellular targets | Medicinal Research Reviews | 2001 | 552 |
11 | Multicomponent domino reactions for the synthesis of biologically active natural products and drugs | Medicinal Research Reviews | 2000 | 524 |
12 | New developments in the chemistry and biology of the bioactive constituents of tanshen | Medicinal Research Reviews | 2007 | 493 |
13 | New insights on the anticancer properties of dietary polyphenols | Medicinal Research Reviews | 2006 | 483 |
14 | Anti-cancer properties of anthraquinones from rhubarb | Medicinal Research Reviews | 2007 | 483 |
15 | Chemistry, biological activity, and chemotherapeutic potential of betulinic acid for the prevention and treatment of cancer and HIV infection | Medicinal Research Reviews | 2004 | 462 |
16 | Recent progress in the development of coumarin derivatives as potent anti-HIV agents | Medicinal Research Reviews | 2003 | 455 |
17 | FGF Receptors: Cancer Biology and Therapeutics | Medicinal Research Reviews | 2014 | 448 |
18 | Boronic acid compounds as potential pharmaceutical agents | Medicinal Research Reviews | 2003 | 443 |
19 | Drugs that target dynamic microtubules: A new molecular perspective | Medicinal Research Reviews | 2011 | 439 |
20 | Gold compounds as anticancer agents: chemistry, cellular pharmacology, and preclinical studies | Medicinal Research Reviews | 2010 | 431 |
21 | The thioredoxin system?From science to clinic | Medicinal Research Reviews | 2004 | 430 |
22 | Bionanotechnology based on silica nanoparticles | Medicinal Research Reviews | 2004 | 430 |
23 | Doxorubicin‐Induced Cardiotoxicity: From Bioenergetic Failure and Cell Death to Cardiomyopathy | Medicinal Research Reviews | 2014 | 429 |
24 | Circulating MicroRNAs: a novel class of biomarkers to diagnose and monitor human cancers | Medicinal Research Reviews | 2012 | 416 |
25 | Anti-mitotic activity of colchicine and the structural basis for its interaction with tubulin | Medicinal Research Reviews | 2008 | 410 |
26 | The ubiquitin-proteasome pathway and proteasome inhibitors | Medicinal Research Reviews | 2001 | 406 |
27 | Abnormal angiogenesis in diabetes mellitus | Medicinal Research Reviews | 2003 | 406 |
28 | Nitric oxide, a double edged sword in cancer biology: Searching for therapeutic opportunities | Medicinal Research Reviews | 2007 | 402 |
29 | Transferrin/transferrin receptor-mediated drug delivery | Medicinal Research Reviews | 2002 | 398 |
30 | Inducible nitric oxide synthase: Regulation, structure, and inhibition | Medicinal Research Reviews | 2020 | 397 |
31 | Recent advances in the multitarget‐directed ligands approach for the treatment of Alzheimer's disease | Medicinal Research Reviews | 2013 | 394 |
32 | Protease inhibitors of the sulfonamide type: Anticancer, antiinflammatory, and antiviral agents | Medicinal Research Reviews | 2003 | 385 |
33 | Chemical and biochemical aspects of platelet activating factor: A novel class of acetylated ether-linked choline-phospholipids | Medicinal Research Reviews | 1985 | 376 |
34 | 4‐Hydroxynonenal: A membrane lipid oxidation product of medicinal interest | Medicinal Research Reviews | 2008 | 376 |
35 | Recent developments in anti‐inflammatory natural products | Medicinal Research Reviews | 2009 | 375 |
36 | Nitrite as regulator of hypoxic signaling in mammalian physiology | Medicinal Research Reviews | 2009 | 373 |
37 | Progress in the chemistry of melanins and related metabolites | Medicinal Research Reviews | 1988 | 370 |
38 | Praziquantel | Medicinal Research Reviews | 1983 | 360 |
39 | Selection criteria for drug-like compounds | Medicinal Research Reviews | 2003 | 345 |
40 | DNA minor groove binders as potential antitumor and antimicrobial agents | Medicinal Research Reviews | 2004 | 343 |
41 | Inhibition of LFA-1/ICAM-1 and VLA-4/VCAM-1 as a therapeutic approach to inflammation and autoimmune diseases | Medicinal Research Reviews | 2002 | 339 |
42 | Lipopeptides from Bacillus and Paenibacillus spp.: A Gold Mine of Antibiotic Candidates | Medicinal Research Reviews | 2016 | 332 |
43 | Carbocyclic nucleosides | Medicinal Research Reviews | 1986 | 329 |
44 | β3 and Atypical β-Adrenoceptors | Medicinal Research Reviews | 1993 | 329 |
45 | Vinyl sulfones: Synthetic preparations and medicinal chemistry applications | Medicinal Research Reviews | 2006 | 326 |
46 | Indole, a core nucleus for potent inhibitors of tubulin polymerization | Medicinal Research Reviews | 2007 | 326 |
47 | Current lead natural products for the chemotherapy of human immunodeficiency virus (HIV) infection | Medicinal Research Reviews | 2000 | 321 |
48 | The chemistry, pharmacology, and clinical applications of qinghaosu (Artemisinin) and its derivatives | Medicinal Research Reviews | 1987 | 318 |
49 | Medicinal Applications of Cyclodextrins | Medicinal Research Reviews | 1994 | 318 |
50 | Cellular and molecular actions of Methylene Blue in the nervous system | Medicinal Research Reviews | 2011 | 314 |