| # | Title | Journal | Year | Citations |
|---|
| 1 | Selective Mitochondrial Autophagy, or Mitophagy, as a Targeted Defense Against Oxidative Stress, Mitochondrial Dysfunction, and Aging | Rejuvenation Research | 2005 | 1,081 |
| 2 | Effects of Different Exercise Interventions on Risk of Falls, Gait Ability, and Balance in Physically Frail Older Adults: A Systematic Review | Rejuvenation Research | 2013 | 673 |
| 3 | Development and Validation of a Multidimensional Prognostic Index for One-Year Mortality from Comprehensive Geriatric Assessment in Hospitalized Older Patients | Rejuvenation Research | 2008 | 397 |
| 4 | Cryoprotectant Toxicity: Facts, Issues, and Questions | Rejuvenation Research | 2015 | 323 |
| 5 | The Role of DNA Methylation in Aging, Rejuvenation, and Age-Related Disease | Rejuvenation Research | 2012 | 307 |
| 6 | Targeting Nonhealing Ulcers of Lower Extremity in Human Through Autologous Bone Marrow-Derived Mesenchymal Stem Cells | Rejuvenation Research | 2009 | 287 |
| 7 | Association of theFOXO3ALocus with Extreme Longevity in a Southern Italian Centenarian Study | Rejuvenation Research | 2009 | 282 |
| 8 | Exercise Attenuates the Major Hallmarks of Aging | Rejuvenation Research | 2015 | 275 |
| 9 | Human Sarcopenia Reveals an Increase in SOCS-3 and Myostatin and a Reduced Efficiency of Akt Phosphorylation | Rejuvenation Research | 2008 | 231 |
| 10 | Therapeutic Efficacy of Intranasally Delivered Mesenchymal Stem Cells in a Rat Model of Parkinson Disease | Rejuvenation Research | 2011 | 225 |
| 11 | Extracellular Redox State: Refining the Definition of Oxidative Stress in Aging | Rejuvenation Research | 2006 | 221 |
| 12 | Evidence That Aging And Amyloid Promote Microglial Cell Senescence | Rejuvenation Research | 2007 | 219 |
| 13 | Exercise Training Promotes SIRT1 Activity in Aged Rats | Rejuvenation Research | 2008 | 215 |
| 14 | Neuropharmacological Review of the Nootropic Herb Bacopa monnieri | Rejuvenation Research | 2013 | 198 |
| 15 | Mitochondrial Oxygen Consumption and Reactive Oxygen Species Production are Independently Modulated: Implications for Aging Studies | Rejuvenation Research | 2007 | 195 |
| 16 | Curcumin Extends Life Span, Improves Health Span, and Modulates the Expression of Age-Associated Aging Genes inDrosophila melanogaster | Rejuvenation Research | 2010 | 195 |
| 17 | Tissue Engineering and Regenerative Medicine: Concepts for Clinical Application | Rejuvenation Research | 2004 | 180 |
| 18 | The Olive Constituent Oleuropein Exhibits Proteasome Stimulatory Properties In Vitro and Confers Life Span Extension of Human Embryonic Fibroblasts | Rejuvenation Research | 2007 | 165 |
| 19 | Autophagy in the Heart and Liver During Normal Aging and Calorie Restriction | Rejuvenation Research | 2007 | 164 |
| 20 | Sleep Facilitates Clearance of Metabolites from the Brain: Glymphatic Function in Aging and Neurodegenerative Diseases | Rejuvenation Research | 2013 | 149 |
| 21 | A Natural Product Telomerase Activator As Part of a Health Maintenance Program | Rejuvenation Research | 2011 | 148 |
| 22 | Association Between Short Physical Performance Battery and Falls in Older People: The Progetto Veneto Anziani Study | Rejuvenation Research | 2014 | 142 |
| 23 | Protective Effects of Intranasal Losartan in the APP/PS1 Transgenic Mouse Model of Alzheimer Disease | Rejuvenation Research | 2010 | 139 |
| 24 | The Plasma NAD+Metabolome Is Dysregulated in “Normal” Aging | Rejuvenation Research | 2019 | 137 |
| 25 | Glucose-Induced Replicative Senescence in Mesenchymal Stem Cells | Rejuvenation Research | 2006 | 130 |
| 26 | Grape Extract Protects Mitochondria from Oxidative Damage and Improves Locomotor Dysfunction and Extends Lifespan in a Drosophila Parkinson's Disease Model | Rejuvenation Research | 2009 | 127 |
| 27 | Aging Theories of Primary Osteoarthritis: From Epidemiology to Molecular Biology | Rejuvenation Research | 2004 | 126 |
| 28 | Consuming a Diet Supplemented with Resveratrol Reduced Infection-Related Neuroinflammation and Deficits in Working Memory in Aged Mice | Rejuvenation Research | 2009 | 123 |
| 29 | The Effect of Age on the Efficacy of Human Mesenchymal Stem Cell Transplantation after a Myocardial Infarction | Rejuvenation Research | 2010 | 123 |
| 30 | Nutrition as a Determinant of Successful Aging: Description of the Quebec Longitudinal Study NuAge and Results from Cross-Sectional Pilot Studies | Rejuvenation Research | 2007 | 122 |
| 31 | Neuroinflammation in Delirium: A Postmortem Case-Control Study | Rejuvenation Research | 2011 | 121 |
| 32 | Erythrocyte Plasma Membrane Redox System in Human Aging | Rejuvenation Research | 2006 | 120 |
| 33 | A Comprehensive Review on Mesenchymal Stem Cell Growth and Senescence | Rejuvenation Research | 2009 | 118 |
| 34 | Increased Plasma Neutrophil Gelatinase-Associated Lipocalin Levels Predict Mortality in Elderly Patients with Chronic Heart Failure | Rejuvenation Research | 2009 | 113 |
| 35 | Cognitive Frailty: A Systematic Review of Epidemiological and Neurobiological Evidence of an Age-Related Clinical Condition | Rejuvenation Research | 2015 | 112 |
| 36 | The Role of Polyphenolic Antioxidants in Health, Disease, and Aging | Rejuvenation Research | 2010 | 111 |
| 37 | A Diet Rich in Olive Oil Phenolics Reduces Oxidative Stress in the Heart of SAMP8 Mice by Induction of Nrf2-Dependent Gene Expression | Rejuvenation Research | 2012 | 111 |
| 38 | Zinc Supplementation in the Elderly Reduces Spontaneous Inflammatory Cytokine Release and Restores T Cell Functions | Rejuvenation Research | 2008 | 108 |
| 39 | Carnisone Increases Efficiency of DOPA Therapy of Parkinson's Disease: A Pilot Study | Rejuvenation Research | 2008 | 106 |
| 40 | Curcumin Prevents Dopaminergic Neuronal Death Through Inhibition of the c-Jun N-Terminal Kinase Pathway | Rejuvenation Research | 2010 | 105 |
| 41 | Cryopreservation of Complex Systems: The Missing Link in the Regenerative Medicine Supply Chain | Rejuvenation Research | 2006 | 104 |
| 42 | N-Glycomic Changes in Serum Proteins During Human Aging | Rejuvenation Research | 2007 | 104 |
| 43 | Circulating Mitochondrial DNA at the Crossroads of Mitochondrial Dysfunction and Inflammation During Aging and Muscle Wasting Disorders | Rejuvenation Research | 2018 | 104 |
| 44 | Association of Dynapenia, Sarcopenia, and Cognitive Impairment Among Community-Dwelling Older Taiwanese | Rejuvenation Research | 2016 | 102 |
| 45 | Characteristics of 400-Meter Walk Test Performance and Subsequent Mortality in Older Adults | Rejuvenation Research | 2009 | 100 |
| 46 | Spermidine and Spermine Are Enriched in Whole Blood of Nona/Centenarians | Rejuvenation Research | 2012 | 100 |
| 47 | Practicality of Intermittent Fasting in Humans and its Effect on Oxidative Stress and Genes Related to Aging and Metabolism | Rejuvenation Research | 2015 | 98 |
| 48 | Forty Percent Methionine Restriction Decreases Mitochondrial Oxygen Radical Production and Leak at Complex I During Forward Electron Flow and Lowers Oxidative Damage to Proteins and Mitochondrial DNA in Rat Kidney and Brain Mitochondria | Rejuvenation Research | 2009 | 96 |
| 49 | D-Galactose Effectiveness in Modeling Aging and Therapeutic Antioxidant Treatment in Mice | Rejuvenation Research | 2010 | 96 |
| 50 | Nuclear DNA Damage as a Direct Cause of Aging | Rejuvenation Research | 2009 | 94 |
