| # | Title | Journal | Year | Citations |
|---|
| 1 | Cytocam-IDF (incident dark field illumination) imaging for bedside monitoring of the microcirculation | Intensive Care Medicine Experimental | 2015 | 183 |
| 2 | In vitro comparison of the adsorption of inflammatory mediators by blood purification devices | Intensive Care Medicine Experimental | 2018 | 165 |
| 3 | Shape descriptors of the “never resting” microglia in three different acute brain injury models in mice | Intensive Care Medicine Experimental | 2015 | 117 |
| 4 | Early and dynamic changes in gene expression in septic shock patients: a genome-wide approach | Intensive Care Medicine Experimental | 2014 | 94 |
| 5 | Sepsis modeling in mice: ligation length is a major severity factor in cecal ligation and puncture | Intensive Care Medicine Experimental | 2016 | 85 |
| 6 | Lung anatomy, energy load, and ventilator-induced lung injury | Intensive Care Medicine Experimental | 2015 | 84 |
| 7 | Body temperature and mouse scoring systems as surrogate markers of death in cecal ligation and puncture sepsis | Intensive Care Medicine Experimental | 2018 | 83 |
| 8 | Personalizing mechanical ventilation according to physiologic parameters to stabilize alveoli and minimize ventilator induced lung injury (VILI) | Intensive Care Medicine Experimental | 2017 | 82 |
| 9 | Serum chloride levels in critical illness—the hidden story | Intensive Care Medicine Experimental | 2018 | 82 |
| 10 | Angiotensin-(1-7) improves oxygenation, while reducing cellular infiltrate and fibrosis in experimental Acute Respiratory Distress Syndrome | Intensive Care Medicine Experimental | 2015 | 81 |
| 11 | The 30-year evolution of airway pressure release ventilation (APRV) | Intensive Care Medicine Experimental | 2016 | 81 |
| 12 | Extracorporeal life support and systemic inflammation | Intensive Care Medicine Experimental | 2019 | 79 |
| 13 | Power to mechanical power to minimize ventilator-induced lung injury? | Intensive Care Medicine Experimental | 2019 | 75 |
| 14 | Patient-ventilator asynchronies during mechanical ventilation: current knowledge and research priorities | Intensive Care Medicine Experimental | 2019 | 73 |
| 15 | Heparins attenuated histone-mediated cytotoxicity in vitro and improved the survival in a rat model of histone-induced organ dysfunction | Intensive Care Medicine Experimental | 2015 | 71 |
| 16 | Assessment of immune organ dysfunction in critical illness: utility of innate immune response markers | Intensive Care Medicine Experimental | 2017 | 71 |
| 17 | Tight junction structure, function, and assessment in the critically ill: a systematic review | Intensive Care Medicine Experimental | 2018 | 69 |
| 18 | Comparison of the source and prognostic utility of cfDNA in trauma and sepsis | Intensive Care Medicine Experimental | 2019 | 66 |
| 19 | Mechanical power at a glance: a simple surrogate for volume-controlled ventilation | Intensive Care Medicine Experimental | 2019 | 65 |
| 20 | Mesenchymal stromal cells are more effective than the MSC secretome in diminishing injury and enhancing recovery following ventilator-induced lung injury | Intensive Care Medicine Experimental | 2015 | 64 |
| 21 | Heparin-binding protein is important for vascular leak in sepsis | Intensive Care Medicine Experimental | 2016 | 64 |
| 22 | Ethical considerations about artificial intelligence for prognostication in intensive care | Intensive Care Medicine Experimental | 2019 | 63 |
| 23 | Endotoxemia and circulating bacteriome in severe COVID-19 patients | Intensive Care Medicine Experimental | 2020 | 62 |
| 24 | Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis | Intensive Care Medicine Experimental | 2018 | 61 |
| 25 | Deletion of Nlrp3 protects from inflammation-induced skeletal muscle atrophy | Intensive Care Medicine Experimental | 2017 | 60 |
| 26 | Role of the adaptive immune response in sepsis | Intensive Care Medicine Experimental | 2020 | 58 |
| 27 | Impact of membrane lung surface area and blood flow on extracorporeal CO2 removal during severe respiratory acidosis | Intensive Care Medicine Experimental | 2017 | 56 |
| 28 | Hyperoxia provokes a time- and dose-dependent inflammatory response in mechanically ventilated mice, irrespective of tidal volumes | Intensive Care Medicine Experimental | 2017 | 55 |
| 29 | Histopathological changes of organ dysfunction in sepsis | Intensive Care Medicine Experimental | 2019 | 50 |
| 30 | Increased glucocorticoid receptor expression in sepsis is related to heat shock proteins, cytokines, and cortisol and is associated with increased mortality | Intensive Care Medicine Experimental | 2017 | 48 |
| 31 | Modulation of monocytes in septic patients: preserved phagocytic activity, increased ROS and NO generation, and decreased production of inflammatory cytokines | Intensive Care Medicine Experimental | 2016 | 47 |
| 32 | Bench to bedside review: therapeutic modulation of nitric oxide in sepsis—an update | Intensive Care Medicine Experimental | 2019 | 46 |
| 33 | Low flow rate alters haemostatic parameters in an ex-vivo extracorporeal membrane oxygenation circuit | Intensive Care Medicine Experimental | 2019 | 45 |
| 34 | Whole blood microRNA markers are associated with acute respiratory distress syndrome | Intensive Care Medicine Experimental | 2017 | 44 |
| 35 | Carbon monoxide in intensive care medicine—time to start the therapeutic application?! | Intensive Care Medicine Experimental | 2020 | 44 |
| 36 | Meta-analysis of targeted temperature management in animal models of cardiac arrest | Intensive Care Medicine Experimental | 2020 | 43 |
| 37 | The effects of airway pressure release ventilation on respiratory mechanics in extrapulmonary lung injury | Intensive Care Medicine Experimental | 2015 | 42 |
| 38 | Myocardial oxidative stress correlates with left ventricular dysfunction on strain echocardiography in a rodent model of sepsis | Intensive Care Medicine Experimental | 2017 | 41 |
| 39 | Adrenomedullin binding improves catecholamine responsiveness and kidney function in resuscitated murine septic shock | Intensive Care Medicine Experimental | 2013 | 40 |
| 40 | Mechanisms of long-term cognitive dysfunction of sepsis: from blood-borne leukocytes to glial cells | Intensive Care Medicine Experimental | 2015 | 40 |
| 41 | The renal compartment: a hydraulic view | Intensive Care Medicine Experimental | 2014 | 39 |
| 42 | Effects of fresh frozen plasma, Ringer’s acetate and albumin on plasma volume and on circulating glycocalyx components following haemorrhagic shock in rats | Intensive Care Medicine Experimental | 2016 | 39 |
| 43 | The role of hypercapnia in acute respiratory failure | Intensive Care Medicine Experimental | 2019 | 39 |
| 44 | The role of high airway pressure and dynamic strain on ventilator-induced lung injury in a heterogeneous acute lung injury model | Intensive Care Medicine Experimental | 2017 | 38 |
| 45 | Heart rate variability in critical care medicine: a systematic review | Intensive Care Medicine Experimental | 2017 | 38 |
| 46 | The diagnostic accuracy for ARDS of global versus regional lung ultrasound scores - a post hoc analysis of an observational study in invasively ventilated ICU patients | Intensive Care Medicine Experimental | 2019 | 37 |
| 47 | Transcriptional profiling of leukocytes in critically ill COVID19 patients: implications for interferon response and coagulation | Intensive Care Medicine Experimental | 2020 | 37 |
| 48 | The metabolic phenotype of rodent sepsis: cause for concern? | Intensive Care Medicine Experimental | 2013 | 36 |
| 49 | Myeloperoxidase can differentiate between sepsis and non-infectious SIRS and predicts mortality in intensive care patients with SIRS | Intensive Care Medicine Experimental | 2017 | 35 |
| 50 | Modulating the distribution and fate of exogenously delivered MSCs to enhance therapeutic potential: knowns and unknowns | Intensive Care Medicine Experimental | 2019 | 35 |
