11.6(top 1%)
impact factor
1.2K(top 20%)
papers
243.5K(top 2%)
citations
269(top 1%)
h-index
12.0(top 1%)
impact factor
1.3K
all documents
252.3K
doc citations
446(top 1%)
g-index

Top Articles

#TitleJournalYearCitations
1Role of Nrf2 in Oxidative Stress and ToxicityAnnual Review of Pharmacology and Toxicology20133,261
2GLUTATHIONE TRANSFERASESAnnual Review of Pharmacology and Toxicology20053,104
3Cell Survival Responses to Environmental Stresses Via the Keap1-Nrf2-ARE PathwayAnnual Review of Pharmacology and Toxicology20073,054
4PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORSAnnual Review of Pharmacology and Toxicology19972,824
5CYCLOOXYGENASES 1 AND 2Annual Review of Pharmacology and Toxicology19982,573
62,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of ToxicityAnnual Review of Pharmacology and Toxicology19822,444
7THE HEME OXYGENASE SYSTEM:A Regulator of Second Messenger GasesAnnual Review of Pharmacology and Toxicology19972,386
8Excitatory Amino Acid TransmittersAnnual Review of Pharmacology and Toxicology19812,318
9The Excitatory Amino Acid Receptors: Their Classes, Pharmacology, and Distinct Properties in the Function of the Central Nervous SystemAnnual Review of Pharmacology and Toxicology19892,136
10BIOCHEMICAL, CELLULAR, AND PHARMACOLOGICAL ASPECTS OF THE MULTIDRUG TRANSPORTERAnnual Review of Pharmacology and Toxicology19991,940
11Efficient Analysis of Experimental ObservationsAnnual Review of Pharmacology and Toxicology19801,753
12Specific Pharmacology of Calcium in Myocardium, Cardiac Pacemakers, and Vascular Smooth MuscleAnnual Review of Pharmacology and Toxicology19771,714
13ACTIVATION OF THEARYLHYDROCARBONRECEPTOR BYSTRUCTURALLYDIVERSEEXOGENOUS ANDENDOGENOUSCHEMICALSAnnual Review of Pharmacology and Toxicology20031,599
14PLEIOTROPIC EFFECTS OF STATINSAnnual Review of Pharmacology and Toxicology20051,574
15Metabotropic Glutamate Receptors: Physiology, Pharmacology, and DiseaseAnnual Review of Pharmacology and Toxicology20101,510
16The Aryl Hydrocarbon Receptor ComplexAnnual Review of Pharmacology and Toxicology19951,506
1714-3-3 Proteins: Structure, Function, and RegulationAnnual Review of Pharmacology and Toxicology20001,427
18Human UDP-Glucuronosyltransferases: Metabolism, Expression, and DiseaseAnnual Review of Pharmacology and Toxicology20001,403
19THEROLE OFOXIDATIVESTRESS INCARCINOGENESISAnnual Review of Pharmacology and Toxicology20041,312
20NEONICOTINOID INSECTICIDE TOXICOLOGY: Mechanisms of Selective ActionAnnual Review of Pharmacology and Toxicology20051,306
21Biosynthesis and Metabolism of Endothelium-Derived Nitric OxideAnnual Review of Pharmacology and Toxicology19901,251
22Neurotoxins that Act on Voltage-Sensitive Sodium Channels in Excitable MembranesAnnual Review of Pharmacology and Toxicology19801,215
23Muscarinic Receptor SubtypesAnnual Review of Pharmacology and Toxicology19901,182
24CRFANDCRF RECEPTORS: Role in Stress Responsivity and Other BehaviorsAnnual Review of Pharmacology and Toxicology20041,159
25Hydrogen Sulfide and Cell SignalingAnnual Review of Pharmacology and Toxicology20111,158
26RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic PlatformAnnual Review of Pharmacology and Toxicology20101,136
27Oxidative Stress in Neurodegenerative DiseasesAnnual Review of Pharmacology and Toxicology19961,127
28REGULATORY MECHANISMS CONTROLLING GENE EXPRESSION MEDIATED BY THE ANTIOXIDANT RESPONSE ELEMENTAnnual Review of Pharmacology and Toxicology20031,127
29CYTOCHROME P-450 3A4: Regulation and Role in Drug MetabolismAnnual Review of Pharmacology and Toxicology19991,121
30Nicotinic Acetylcholine Receptors and Nicotinic Cholinergic Mechanisms of the Central Nervous SystemAnnual Review of Pharmacology and Toxicology20071,072
31Mitochondrial Oxidative Stress: Implications for Cell DeathAnnual Review of Pharmacology and Toxicology20071,068
32Superoxide Radical: An Endogenous ToxicantAnnual Review of Pharmacology and Toxicology19831,064
33Mechanisms of Cell Protection by Heme Oxygenase-1Annual Review of Pharmacology and Toxicology20101,057
34The Function of Myosin and Myosin Light Chain Kinase Phosphorylation in Smooth MuscleAnnual Review of Pharmacology and Toxicology19851,042
35INDUCTION OF CYTOCHROME P4501A1Annual Review of Pharmacology and Toxicology19991,014
36Targeting Antioxidants to Mitochondria by Conjugation to Lipophilic CationsAnnual Review of Pharmacology and Toxicology20071,010
37METALLOTHIONEIN: An Intracellular Protein to Protect Against Cadmium ToxicityAnnual Review of Pharmacology and Toxicology19991,009
38REGULATION OF GENE EXPRESSION BY REACTIVE OXYGENAnnual Review of Pharmacology and Toxicology1999980
39The PAS Superfamily: Sensors of Environmental and Developmental SignalsAnnual Review of Pharmacology and Toxicology2000959
40THE ROLE OF RECEPTOR KINASES AND ARRESTINS IN G PROTEIN–COUPLED RECEPTOR REGULATIONAnnual Review of Pharmacology and Toxicology1998955
41PROSTANOIDRECEPTORS: Subtypes and SignalingAnnual Review of Pharmacology and Toxicology2001927
42The Role of Endothelium in the Responses of Vascular Smooth Muscle to DrugsAnnual Review of Pharmacology and Toxicology1984925
43Biomarkers of Acute Kidney InjuryAnnual Review of Pharmacology and Toxicology2008925
44Mechanism-Based Concepts of Size and Maturity in PharmacokineticsAnnual Review of Pharmacology and Toxicology2008910
45Structure-Function of the G Protein–Coupled Receptor SuperfamilyAnnual Review of Pharmacology and Toxicology2013907
46MOLECULARAPPROACH TOADENOSINERECEPTORS: Receptor-Mediated Mechanisms of Tissue ProtectionAnnual Review of Pharmacology and Toxicology2001886
47INHIBITION OFCARCINOGENESIS BYTEAAnnual Review of Pharmacology and Toxicology2002861
48Toxicology of Hydrogen SulfideAnnual Review of Pharmacology and Toxicology1992842
49Complexity and Diversity of Mammalian Adenylyl CyclasesAnnual Review of Pharmacology and Toxicology1996804
50G PROTEIN βγ SUBUNITSAnnual Review of Pharmacology and Toxicology1997791