Molecular Therapy - Nucleic Acids

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64.9K(top 5%)

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Top Articles

#	Title	Journal	Year	Citations
1	Off-target Effects in CRISPR/Cas9-mediated Genome Engineering	Molecular Therapy - Nucleic Acids	2015	872
2	siRNA Versus miRNA as Therapeutics for Gene Silencing	Molecular Therapy - Nucleic Acids	2015	730
3	Therapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Generation Medicine	Molecular Therapy - Nucleic Acids	2017	600
4	Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines	Molecular Therapy - Nucleic Acids	2019	451
5	Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA	Molecular Therapy - Nucleic Acids	2012	445
6	Oligonucleotide Aptamers: New Tools for Targeted Cancer Therapy	Molecular Therapy - Nucleic Acids	2014	430
7	Delivery of Functional Anti-miR-9 by Mesenchymal Stem Cell–derived Exosomes to Glioblastoma Multiforme Cells Conferred Chemosensitivity	Molecular Therapy - Nucleic Acids	2013	422
8	Mir-34: A New Weapon Against Cancer?	Molecular Therapy - Nucleic Acids	2014	421
9	Exosome Mediated Delivery of miR-124 Promotes Neurogenesis after Ischemia	Molecular Therapy - Nucleic Acids	2017	416
10	Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents	Molecular Therapy - Nucleic Acids	2014	412
11	TanCAR: A Novel Bispecific Chimeric Antigen Receptor for Cancer Immunotherapy	Molecular Therapy - Nucleic Acids	2013	371
12	Circular RNAs in Cancer	Molecular Therapy - Nucleic Acids	2019	325
13	The CRISPR/Cas9 System Facilitates Clearance of the Intrahepatic HBV Templates In Vivo	Molecular Therapy - Nucleic Acids	2014	319
14	COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites	Molecular Therapy - Nucleic Acids	2014	315
15	BEAMing and Droplet Digital PCR Analysis of Mutant IDH1 mRNA in Glioma Patient Serum and Cerebrospinal Fluid Extracellular Vesicles	Molecular Therapy - Nucleic Acids	2013	284
16	A Facile Method for the Removal of dsRNA Contaminant from In Vitro-Transcribed mRNA	Molecular Therapy - Nucleic Acids	2019	271
17	iRNA-PseColl: Identifying the Occurrence Sites of Different RNA Modifications by Incorporating Collective Effects of Nucleotides into PseKNC	Molecular Therapy - Nucleic Acids	2017	259
18	Aptamer Selection Technology and Recent Advances	Molecular Therapy - Nucleic Acids	2015	250
19	The Promising Role of miR-21 as a Cancer Biomarker and Its Importance in RNA-Based Therapeutics	Molecular Therapy - Nucleic Acids	2020	242
20	Influence of Polyethylene Glycol Lipid Desorption Rates on Pharmacokinetics and Pharmacodynamics of siRNA Lipid Nanoparticles	Molecular Therapy - Nucleic Acids	2013	241
21	Targeting Hepatitis B Virus With CRISPR/Cas9	Molecular Therapy - Nucleic Acids	2014	240
22	miR-1289 and “Zipcode”-like Sequence Enrich mRNAs in Microvesicles	Molecular Therapy - Nucleic Acids	2012	235
23	2L-piRNA: A Two-Layer Ensemble Classifier for Identifying Piwi-Interacting RNAs and Their Function	Molecular Therapy - Nucleic Acids	2017	226
24	Preclinical and Clinical Advances of GalNAc-Decorated Nucleic Acid Therapeutics	Molecular Therapy - Nucleic Acids	2017	221
25	Therapeutic Delivery of MicroRNA-29b by Cationic Lipoplexes for Lung Cancer	Molecular Therapy - Nucleic Acids	2013	201
26	Cell-type-specific, Aptamer-functionalized Agents for Targeted Disease Therapy	Molecular Therapy - Nucleic Acids	2014	201
27	Long Intergenic Noncoding RNA 00511 Acts as an Oncogene in Non–small-cell Lung Cancer by Binding to EZH2 and Suppressing p57	Molecular Therapy - Nucleic Acids	2016	192
28	The MSC-Derived Exosomal lncRNA H19 Promotes Wound Healing in Diabetic Foot Ulcers by Upregulating PTEN via MicroRNA-152-3p	Molecular Therapy - Nucleic Acids	2020	192
29	FASTAptamer: A Bioinformatic Toolkit for High-throughput Sequence Analysis of Combinatorial Selections	Molecular Therapy - Nucleic Acids	2015	189
30	Meta-4mCpred: A Sequence-Based Meta-Predictor for Accurate DNA 4mC Site Prediction Using Effective Feature Representation	Molecular Therapy - Nucleic Acids	2019	182
31	Characterization of the Immune Cell Infiltration Landscape in Head and Neck Squamous Cell Carcinoma to Aid Immunotherapy	Molecular Therapy - Nucleic Acids	2020	181
32	Hepatocellular Carcinoma Cell-Secreted Exosomal MicroRNA-210 Promotes Angiogenesis In Vitro and In Vivo	Molecular Therapy - Nucleic Acids	2018	178
33	Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification	Molecular Therapy - Nucleic Acids	2018	178
34	Emerging Epigenetic Regulation of Circular RNAs in Human Cancer	Molecular Therapy - Nucleic Acids	2019	178
35	Pip6-PMO, A New Generation of Peptide-oligonucleotide Conjugates With Improved Cardiac Exon Skipping Activity for DMD Treatment	Molecular Therapy - Nucleic Acids	2012	177
36	iRNA-3typeA: Identifying Three Types of Modification at RNA’s Adenosine Sites	Molecular Therapy - Nucleic Acids	2018	173
37	iRNA-PseU: Identifying RNA pseudouridine sites	Molecular Therapy - Nucleic Acids	2016	172
38	The MicroRNA Biology of the Mammalian Nucleus	Molecular Therapy - Nucleic Acids	2014	171
39	LRRK2 Antisense Oligonucleotides Ameliorate α-Synuclein Inclusion Formation in a Parkinson’s Disease Mouse Model	Molecular Therapy - Nucleic Acids	2017	167
40	M6APred-EL: A Sequence-Based Predictor for Identifying N6-methyladenosine Sites Using Ensemble Learning	Molecular Therapy - Nucleic Acids	2018	167
41	circFBXW7 Inhibits Malignant Progression by Sponging miR-197-3p and Encoding a 185-aa Protein in Triple-Negative Breast Cancer	Molecular Therapy - Nucleic Acids	2019	167
42	LncRNA UCA1, Upregulated in CRC Biopsies and Downregulated in Serum Exosomes, Controls mRNA Expression by RNA-RNA Interactions	Molecular Therapy - Nucleic Acids	2018	163
43	In vivo SELEX for Identification of Brain-penetrating Aptamers	Molecular Therapy - Nucleic Acids	2013	159
44	Epigenetic Regulation of m6A Modifications in Human Cancer	Molecular Therapy - Nucleic Acids	2020	159
45	Immune-Related lncRNA to Construct Novel Signature and Predict the Immune Landscape of Human Hepatocellular Carcinoma	Molecular Therapy - Nucleic Acids	2020	155
46	miR-93-5p-Containing Exosomes Treatment Attenuates Acute Myocardial Infarction-Induced Myocardial Damage	Molecular Therapy - Nucleic Acids	2018	150
47	Synthetic Circular RNA Functions as a miR-21 Sponge to Suppress Gastric Carcinoma Cell Proliferation	Molecular Therapy - Nucleic Acids	2018	150
48	In vivo Editing of the Human Mutant Rhodopsin Gene by Electroporation of Plasmid-based CRISPR/Cas9 in the Mouse Retina	Molecular Therapy - Nucleic Acids	2016	147
49	Circular RNA Cdr1as Upregulates SCAI to Suppress Cisplatin Resistance in Ovarian Cancer via miR-1270 Suppression	Molecular Therapy - Nucleic Acids	2019	147
50	Exosomes in Cancer Liquid Biopsy: A Focus on Breast Cancer	Molecular Therapy - Nucleic Acids	2018	146

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Molecular Therapy - Nucleic Acids

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