| # | Title | Journal | Year | Citations |
|---|
| 1 | Modeling Physiological Events in 2D vs. 3D Cell Culture | Physiology | 2017 | 1,069 |
| 2 | Hydroxylation of HIF-1: Oxygen Sensing at the Molecular Level | Physiology | 2004 | 732 |
| 3 | Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor 1 | Physiology | 2009 | 728 |
| 4 | Signaling in Muscle Atrophy and Hypertrophy | Physiology | 2008 | 622 |
| 5 | Membrane Microparticles: Two Sides of the Coin | Physiology | 2005 | 563 |
| 6 | The mTOR Pathway in the Control of Protein Synthesis | Physiology | 2006 | 549 |
| 7 | Exercise is the Real Polypill | Physiology | 2013 | 486 |
| 8 | Development of Structures and Transport Functions in the Mouse Placenta | Physiology | 2005 | 463 |
| 9 | Linking Gut Microbiota and Inflammation to Obesity and Insulin Resistance | Physiology | 2016 | 463 |
| 10 | AMPK: A Key Sensor of Fuel and Energy Status in Skeletal Muscle | Physiology | 2006 | 434 |
| 11 | The Bone Marrow Vascular Niche: Home of HSC Differentiation and Mobilization | Physiology | 2005 | 406 |
| 12 | Melatonin: Exceeding Expectations | Physiology | 2014 | 401 |
| 13 | Lipid Rafts, Detergent-Resistant Membranes, and Raft Targeting Signals | Physiology | 2006 | 400 |
| 14 | Endoplasmic Reticulum Stress: Signaling the Unfolded Protein Response | Physiology | 2007 | 388 |
| 15 | Matrix Metalloproteinase-9: Many Shades of Function in Cardiovascular Disease | Physiology | 2013 | 385 |
| 16 | Preeclampsia: The Role of Angiogenic Factors in Its Pathogenesis | Physiology | 2009 | 384 |
| 17 | The pH of the Secretory Pathway: Measurement, Determinants, and Regulation | Physiology | 2004 | 371 |
| 18 | Calcium-Activated Potassium Channels and the Regulation of Vascular Tone | Physiology | 2006 | 368 |
| 19 | Intrauterine Programming of Physiological Systems: Causes and Consequences | Physiology | 2006 | 367 |
| 20 | Maternal Uterine Vascular Remodeling During Pregnancy | Physiology | 2009 | 349 |
| 21 | Mitochondria: The Hub of Cellular Ca2+Signaling | Physiology | 2008 | 342 |
| 22 | Roles for Growth Factors in Cancer Progression | Physiology | 2010 | 342 |
| 23 | Breathtaking TRP Channels: TRPA1 and TRPV1 in Airway Chemosensation and Reflex Control | Physiology | 2008 | 340 |
| 24 | Phagocytosis of Retinal Rod and Cone Photoreceptors | Physiology | 2010 | 339 |
| 25 | The Regulation and Physiology of Mitochondrial Proton Leak | Physiology | 2011 | 335 |
| 26 | Morphological Features of Cell Death | Physiology | 2004 | 318 |
| 27 | Mirror Neurons and Mirror Systems in Monkeys and Humans | Physiology | 2008 | 309 |
| 28 | Myosins: Tails (and Heads) of Functional Diversity | Physiology | 2005 | 300 |
| 29 | Physiological Bone Remodeling: Systemic Regulation and Growth Factor Involvement | Physiology | 2016 | 290 |
| 30 | Altered Cardiac Myocyte Ca Regulation In Heart Failure | Physiology | 2006 | 279 |
| 31 | Broca’s Region: From Action to Language | Physiology | 2005 | 274 |
| 32 | Brain Glucose Sensing, Counterregulation, and Energy Homeostasis | Physiology | 2007 | 273 |
| 33 | Aging of the Immune System as a Prognostic Factor for Human Longevity | Physiology | 2008 | 273 |
| 34 | Stretch-Activated Ion Channels: What Are They? | Physiology | 2010 | 267 |
| 35 | The Molecular Physiology of Tight Junction Pores | Physiology | 2004 | 266 |
| 36 | Skeletal Muscle Glucose Uptake During Exercise: How is it Regulated? | Physiology | 2005 | 265 |
| 37 | Islet Inflammation Impairs the Pancreatic β-Cell in Type 2 Diabetes | Physiology | 2009 | 264 |
| 38 | Sex-Based Differences in Skeletal Muscle Kinetics and Fiber-Type Composition | Physiology | 2015 | 263 |
| 39 | Molecular Physiology of Urate Transport | Physiology | 2005 | 261 |
| 40 | Gamma Oscillations in the Hippocampus | Physiology | 2010 | 260 |
| 41 | The Rocking Bundle: A Mechanism for Ion-Coupled Solute Flux by Symmetrical Transporters | Physiology | 2009 | 253 |
| 42 | Heat Waves, the New Normal: Summertime Temperature Extremes Will Impact Animals, Ecosystems, and Human Communities | Physiology | 2019 | 252 |
| 43 | Voltage-Gated Potassium Channels in Cell Proliferation | Physiology | 2004 | 251 |
| 44 | Extracellular Vesicles: Exosomes and Microvesicles, Integrators of Homeostasis | Physiology | 2019 | 250 |
| 45 | Erythrocytes: Oxygen Sensors and Modulators of Vascular Tone | Physiology | 2009 | 247 |
| 46 | The Architecture of the Active Zone in the Presynaptic Nerve Terminal | Physiology | 2004 | 244 |
| 47 | Structure and Function of ABC Transporters | Physiology | 2007 | 243 |
| 48 | Imaging CNS Modulation of Pain in Humans | Physiology | 2008 | 233 |
| 49 | Muscle Fatigue: Lactic Acid or Inorganic Phosphate the Major Cause? | Physiology | 2002 | 229 |
| 50 | Energy Landscapes as a Tool to Integrate GPCR Structure, Dynamics, and Function | Physiology | 2010 | 227 |
