# | Title | Journal | Year | Citations |
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1 | A comprehensive definition for metabolic syndrome | DMM Disease Models and Mechanisms | 2009 | 1,392 |
2 | Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer | DMM Disease Models and Mechanisms | 2011 | 1,248 |
3 | How informative is the mouse for human gut microbiota research? | DMM Disease Models and Mechanisms | 2015 | 990 |
4 | Cellular and molecular mechanisms of muscle atrophy | DMM Disease Models and Mechanisms | 2013 | 958 |
5 | Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling | DMM Disease Models and Mechanisms | 2010 | 627 |
6 | Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development | DMM Disease Models and Mechanisms | 2013 | 609 |
7 | Standard operating procedures for describing and performing metabolic tests of glucose homeostasis in mice | DMM Disease Models and Mechanisms | 2010 | 606 |
8 | Hypothalamic circuits regulating appetite and energy homeostasis: pathways to obesity | DMM Disease Models and Mechanisms | 2017 | 515 |
9 | Neurodegenerative disease: models, mechanisms, and a new hope | DMM Disease Models and Mechanisms | 2017 | 508 |
10 | A high-sugar diet produces obesity and insulin resistance in wild-typeDrosophila | DMM Disease Models and Mechanisms | 2011 | 466 |
11 | Rodent models in neuroscience research: is it a rat race? | DMM Disease Models and Mechanisms | 2016 | 452 |
12 | Diverse functions of matrix metalloproteinases during fibrosis | DMM Disease Models and Mechanisms | 2014 | 404 |
13 | A peek into cancer-associated fibroblasts: origins, functions and translational impact | DMM Disease Models and Mechanisms | 2018 | 400 |
14 | Animal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapy | DMM Disease Models and Mechanisms | 2015 | 376 |
15 | Mouse xenograft models vs GEM models for human cancer therapeutics | DMM Disease Models and Mechanisms | 2008 | 373 |
16 | Drosophilatools and assays for the study of human diseases | DMM Disease Models and Mechanisms | 2016 | 367 |
17 | Anti-obesity drugs: past, present and future | DMM Disease Models and Mechanisms | 2012 | 360 |
18 | Mouse models of allergic asthma: acute and chronic allergen challenge | DMM Disease Models and Mechanisms | 2008 | 338 |
19 | Clinical challenges of chronic wounds: searching for an optimal animal model to recapitulate their complexity | DMM Disease Models and Mechanisms | 2014 | 337 |
20 | A model 450 million years in the making: zebrafish and vertebrate immunity | DMM Disease Models and Mechanisms | 2012 | 307 |
21 | The ferret as a model organism to study influenza A virus infection | DMM Disease Models and Mechanisms | 2011 | 300 |
22 | Degeneration and regeneration of the intervertebral disc: lessons from development | DMM Disease Models and Mechanisms | 2011 | 295 |
23 | The adipose organ at a glance | DMM Disease Models and Mechanisms | 2012 | 291 |
24 | The pathophysiology of traumatic brain injury at a glance | DMM Disease Models and Mechanisms | 2013 | 286 |
25 | Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease | DMM Disease Models and Mechanisms | 2012 | 285 |
26 | An innate immune response of blood cells to tumors and tissue damage in Drosophila | DMM Disease Models and Mechanisms | 2008 | 267 |
27 | Set points, settling points and some alternative models: theoretical options to understand how genes and environments combine to regulate body adiposity | DMM Disease Models and Mechanisms | 2011 | 266 |
28 | Rat models of spinal cord injury: from pathology to potential therapies | DMM Disease Models and Mechanisms | 2016 | 265 |
29 | Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture | DMM Disease Models and Mechanisms | 2012 | 264 |
30 | Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice | DMM Disease Models and Mechanisms | 2009 | 254 |
31 | Drosophila melanogaster as a model for human intestinal infection and pathology | DMM Disease Models and Mechanisms | 2011 | 254 |
32 | Dysregulation of cholesterol balance in the brain: contribution to neurodegenerative diseases | DMM Disease Models and Mechanisms | 2012 | 254 |
33 | Disease modelling in human organoids | DMM Disease Models and Mechanisms | 2019 | 254 |
34 | Mechanisms of protein-folding diseases at a glance | DMM Disease Models and Mechanisms | 2014 | 251 |
35 | Lactate shuttles at a glance: from physiological paradigms to anti-cancer treatments | DMM Disease Models and Mechanisms | 2011 | 245 |
36 | SFARI Gene: an evolving database for the autism research community | DMM Disease Models and Mechanisms | 2010 | 244 |
37 | Preeclampsia: multiple approaches for a multifactorial disease | DMM Disease Models and Mechanisms | 2012 | 240 |
38 | Mouse models of graft-versus-host disease: advances and limitations | DMM Disease Models and Mechanisms | 2011 | 238 |
39 | Experimental myocardial infarction triggers canonical Wnt signaling and endothelial-to-mesenchymal transition | DMM Disease Models and Mechanisms | 2011 | 237 |
40 | Rodent models of diabetic cardiomyopathy | DMM Disease Models and Mechanisms | 2009 | 231 |
41 | miRNA interplay: mechanisms and consequences in cancer | DMM Disease Models and Mechanisms | 2021 | 230 |
42 | Update on animal models of diabetic retinopathy: from molecular approaches to mice and higher mammals | DMM Disease Models and Mechanisms | 2012 | 229 |
43 | Rats! | DMM Disease Models and Mechanisms | 2009 | 219 |
44 | Mouse models of metastasis: progress and prospects | DMM Disease Models and Mechanisms | 2017 | 216 |
45 | Mouse models of the metabolic syndrome | DMM Disease Models and Mechanisms | 2010 | 215 |
46 | The emerging use of zebrafish to model metabolic disease | DMM Disease Models and Mechanisms | 2013 | 214 |
47 | Biology and therapy of inherited retinal degenerative disease: insights from mouse models | DMM Disease Models and Mechanisms | 2015 | 207 |
48 | Addressing variability in iPSC-derived models of human disease: guidelines to promote reproducibility | DMM Disease Models and Mechanisms | 2020 | 205 |
49 | Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models | DMM Disease Models and Mechanisms | 2013 | 201 |
50 | Neuronal regeneration in a zebrafish model of adult brain injury | DMM Disease Models and Mechanisms | 2012 | 194 |