# | Title | Journal | Year | Citations |
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1 | A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays | Journal of Biomolecular Screening | 1999 | 6,128 |
2 | High-Density Miniaturized Thermal Shift Assays as a General Strategy for Drug Discovery | Journal of Biomolecular Screening | 2001 | 782 |
3 | The Use of 3-D Cultures for High-Throughput Screening: The Multicellular Spheroid Model | Journal of Biomolecular Screening | 2004 | 689 |
4 | Rapid Generation of Single-Tumor Spheroids for High-Throughput Cell Function and Toxicity Analysis | Journal of Biomolecular Screening | 2006 | 488 |
5 | Improved Statistical Methods for Hit Selection in High-Throughput Screening | Journal of Biomolecular Screening | 2003 | 306 |
6 | Fluorescence Polarization and Anisotropy in High Throughput Screening: Perspectives and Primer | Journal of Biomolecular Screening | 2000 | 291 |
7 | Using Extended-Connectivity Fingerprints with Laplacian-Modified Bayesian Analysis in High-Throughput Screening Follow-Up | Journal of Biomolecular Screening | 2005 | 259 |
8 | A New Perspective in the Field of Cardiac Safety Testing through the Comprehensive In Vitro Proarrhythmia Assay Paradigm | Journal of Biomolecular Screening | 2016 | 259 |
9 | Label-Free Assays on the BIND System | Journal of Biomolecular Screening | 2004 | 245 |
10 | A Simple Technique for Reducing Edge Effect in Cell-Based Assays | Journal of Biomolecular Screening | 2003 | 232 |
11 | IonWorks™ HT: A New High-Throughput Electrophysiology Measurement Platform | Journal of Biomolecular Screening | 2003 | 232 |
12 | Chagas Disease Drug Discovery: Toward a New Era | Journal of Biomolecular Screening | 2015 | 227 |
13 | The Future of High-Throughput Screening | Journal of Biomolecular Screening | 2008 | 213 |
14 | Development of High Throughput Screening Assays Using Fluorescence Polarization: Nuclear Receptor-Ligand-Binding and Kinase/Phosphatase Assays | Journal of Biomolecular Screening | 2000 | 212 |
15 | High-Content Screening: A New Approach to Easing Key Bottlenecks in the Drug Discovery Process | Journal of Biomolecular Screening | 1997 | 208 |
16 | A New Bliss Independence Model to Analyze Drug Combination Data | Journal of Biomolecular Screening | 2014 | 207 |
17 | A Comparison of Assay Performance Measures in Screening Assays: Signal Window, Z' Factor, and Assay Variability Ratio | Journal of Biomolecular Screening | 2006 | 204 |
18 | Dynamic Monitoring of Cell Adhesion and Spreading on Microelectronic Sensor Arrays | Journal of Biomolecular Screening | 2005 | 202 |
19 | FLIPR: A New Instrument for Accurate, High Throughput Optical Screening | Journal of Biomolecular Screening | 1996 | 196 |
20 | High Throughput Prediction of Oral Absorption: Improvement of the Composition of the Lipid Solution Used in Parallel Artificial Membrane Permeation Assay | Journal of Biomolecular Screening | 2001 | 191 |
21 | Comparison of the Usefulness of the MTT, ATP, and Calcein Assays to Predict the Potency of Cytotoxic Agents in Various Human Cancer Cell Lines | Journal of Biomolecular Screening | 2004 | 189 |
22 | High-Throughput Screening: Update on Practices and Success | Journal of Biomolecular Screening | 2006 | 189 |
23 | High-Throughput Screening of G Protein-Coupled Receptor Antagonists Using a Bioluminescence Resonance Energy Transfer 1-Based β-Arrestin2 Recruitment Assay | Journal of Biomolecular Screening | 2005 | 181 |
24 | Fluorescence Polarization Competition Assay: The Range of Resolvable Inhibitor Potency Is Limited by the Affinity of the Fluorescent Ligand | Journal of Biomolecular Screening | 2003 | 178 |
25 | A Reliable Tool to Determine Cell Viability in Complex 3-D Culture: The Acid Phosphatase Assay | Journal of Biomolecular Screening | 2007 | 178 |
26 | Universal Screening Methods and Applications of ThermoFluor® | Journal of Biomolecular Screening | 2006 | 167 |
27 | Illustration of SSMD, z Score, SSMD*, z* Score, and t Statistic for Hit Selection in RNAi High-Throughput Screens | Journal of Biomolecular Screening | 2011 | 166 |
28 | Comparison of Methods for Image-Based Profiling of Cellular Morphological Responses to Small-Molecule Treatment | Journal of Biomolecular Screening | 2013 | 166 |
29 | Increasing the Content of High-Content Screening: An Overview | Journal of Biomolecular Screening | 2014 | 166 |
30 | Median Absolute Deviation to Improve Hit Selection for Genome-Scale RNAi Screens | Journal of Biomolecular Screening | 2008 | 163 |
31 | A Thallium-Sensitive, Fluorescence-Based Assay for Detecting and Characterizing Potassium Channel Modulators in Mammalian Cells | Journal of Biomolecular Screening | 2004 | 158 |
32 | Characterization of Differentiated SH-SY5Y as Neuronal Screening Model Reveals Increased Oxidative Vulnerability | Journal of Biomolecular Screening | 2016 | 157 |
33 | An AlphaScreen®-Based Assay for High-Throughput Screening for Specific Inhibitors of Nuclear Import | Journal of Biomolecular Screening | 2011 | 151 |
34 | Screening β-Arrestin Recruitment for the Identification of Natural Ligands for Orphan G-Protein–Coupled Receptors | Journal of Biomolecular Screening | 2013 | 145 |
35 | A Simplified Method for Quantifying Cell Migration/Wound Healing in 96-Well Plates | Journal of Biomolecular Screening | 2010 | 142 |
36 | A Novel Membrane Potential-Sensitive Fluorescent Dye Improves Cell-Based Assays for Ion Channels | Journal of Biomolecular Screening | 2002 | 141 |
37 | Epigenetic Drug Discovery: Targeting DNA Methyltransferases | Journal of Biomolecular Screening | 2012 | 138 |
38 | SIRT1 Modulating Compounds from High-Throughput Screening as Anti-Inflammatory and Insulin-Sensitizing Agents | Journal of Biomolecular Screening | 2006 | 137 |
39 | Application of a High-Content Multiparameter Cytotoxicity Assay to Prioritize Compounds Based on Toxicity Potential in Humans | Journal of Biomolecular Screening | 2008 | 137 |
40 | A Fluorescent Ligand-Binding Alternative Using Tag-lite® Technology | Journal of Biomolecular Screening | 2010 | 135 |
41 | Population Patch Clamp Improves Data Consistency and Success Rates in the Measurement of Ionic Currents | Journal of Biomolecular Screening | 2006 | 133 |
42 | Are GPCRs Still a Source of New Targets? | Journal of Biomolecular Screening | 2013 | 133 |
43 | DMSO-Related Effects in Protein Characterization | Journal of Biomolecular Screening | 2006 | 131 |
44 | Multiparameter In Vitro Assessment of Compound Effects on Cardiomyocyte Physiology Using iPSC Cells | Journal of Biomolecular Screening | 2013 | 130 |
45 | A Comparison of ALPHAScreen, TR-FRET, and TRF as Assay Methods for FXR Nuclear Receptors | Journal of Biomolecular Screening | 2002 | 128 |
46 | A High-Throughput Cell-Based Assay for Inhibitors of ABCG2 Activity | Journal of Biomolecular Screening | 2006 | 128 |
47 | Sirtuin 1 (SIRT1): The Misunderstood HDAC | Journal of Biomolecular Screening | 2011 | 128 |
48 | Modulation of NF-κB Signaling as a Therapeutic Target in Autoimmunity | Journal of Biomolecular Screening | 2016 | 122 |
49 | HTRF® Technology | Journal of Biomolecular Screening | 1999 | 121 |
50 | Optimization of a Higher Throughput Microsomal Stability Screening Assay for Profiling Drug Discovery Candidates | Journal of Biomolecular Screening | 2003 | 120 |