Current Topics in Medicinal Chemistry

2.6(top 20%)

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4.1K(top 5%)

papers

122.6K(top 5%)

citations

130(top 5%)

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2.8(top 20%)

extended IF

4.6K

all documents

128.6K

doc citations

198(top 5%)

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Top Articles

#	Title	Journal	Year	Citations
1	Toxic Metals and Oxidative Stress Part I: Mechanisms Involved in Me-tal induced Oxidative Damage	Current Topics in Medicinal Chemistry	2001	1,573
2	Sulfur Containing Scaffolds in Drugs: Synthesis and Application in Medicinal Chemistry	Current Topics in Medicinal Chemistry	2016	1,269
3	Chemical and Physical Properties and Potential Mechanisms: Melatonin as a Broad Spectrum Antioxidant and Free Radical Scavenger	Current Topics in Medicinal Chemistry	2002	885
4	Subunit Composition, Distribution and Function of GABA-A Receptor Subtypes	Current Topics in Medicinal Chemistry	2002	832
5	Medicinal Chemistry and the Molecular Operating Environment (MOE): Application of QSAR and Molecular Docking to Drug Discovery	Current Topics in Medicinal Chemistry	2008	831
6	Structure-Based Virtual Screening for Drug Discovery: Principles, Applications and Recent Advances	Current Topics in Medicinal Chemistry	2014	706
7	Surface Chemistry Influences Implant Biocompatibility	Current Topics in Medicinal Chemistry	2008	671
8	3D-QSAR in Drug Design - A Review	Current Topics in Medicinal Chemistry	2010	628
9	Physicochemical Profiling (Solubility, Permeability and Charge State)	Current Topics in Medicinal Chemistry	2001	547
10	Ruthenium Antimetastatic Agents	Current Topics in Medicinal Chemistry	2004	452
11	The Significance of Chirality in Drug Design and Development	Current Topics in Medicinal Chemistry	2011	440
12	Oxytosis: A Novel Form of Programmed Cell Death	Current Topics in Medicinal Chemistry	2001	428
13	Melatonin-Immune System Relationships	Current Topics in Medicinal Chemistry	2002	404
14	Peptidylprolyl Cis / Trans Isomerases (Immunophilins): Biological Diversity - Targets - Functions	Current Topics in Medicinal Chemistry	2003	338
15	Melatonin as a Chronobiotic / Anticancer Agent: Cellular, Biochemical, and Molecular Mechanisms of Action and their Implications for Circadian-Based Cancer Therapy	Current Topics in Medicinal Chemistry	2002	332
16	Mechanisms of Action of Antiepileptic Drugs	Current Topics in Medicinal Chemistry	2005	326
17	Antimicrobial Peptide Structure and Mechanism of Action: A Focus on the Role of Membrane Structure	Current Topics in Medicinal Chemistry	2015	313
18	The Biology of p38 Kinase: A Central Role in Inflammation	Current Topics in Medicinal Chemistry	2005	297
19	Successful Applications of Computer Aided Drug Discovery: Moving Drugs from Concept to the Clinic	Current Topics in Medicinal Chemistry	2010	295
20	Quinolones: Action and Resistance Updated	Current Topics in Medicinal Chemistry	2009	292
21	Role of Flavonoids in Oxidative Stress	Current Topics in Medicinal Chemistry	2001	287
22	Trifluoromethyl Ethers and –Thioethers as Tools for Medicinal Chemistry and Drug Discovery	Current Topics in Medicinal Chemistry	2014	281
23	Eicosanoids in Inflammation: Biosynthesis, Pharmacology, and Therapeutic Frontiers	Current Topics in Medicinal Chemistry	2007	275
24	Fluoroquinolones: Action and Resistance	Current Topics in Medicinal Chemistry	2003	273
25	Medicinal Chemistry and Bioinformatics - Current Trends in Drugs Discovery with Networks Topological Indices	Current Topics in Medicinal Chemistry	2007	271
26	Update on Hsp90 Inhibitors in Clinical Trial	Current Topics in Medicinal Chemistry	2009	263
27	The ATP-Binding Site of Type II Topoisomerases as a Target for Antibacterial Drugs	Current Topics in Medicinal Chemistry	2003	257
28	An Unprecedented Revolution in Medicinal Chemistry Driven by the Progress of Biological Science	Current Topics in Medicinal Chemistry	2017	252
29	Molecular Biology of Serotonin Receptors - Structure and Function at the Molecular Level	Current Topics in Medicinal Chemistry	2002	243
30	Ligand Docking and Structure-based Virtual Screening in Drug Discovery	Current Topics in Medicinal Chemistry	2007	241
31	Opioid Receptors and their Ligands	Current Topics in Medicinal Chemistry	2004	240
32	Thiazole: A Review on Chemistry, Synthesis and Therapeutic Importance of its Derivatives	Current Topics in Medicinal Chemistry	2016	236
33	Estrogen Receptors as Therapeutic Targets in Breast Cancer	Current Topics in Medicinal Chemistry	2006	234
34	Novel Anti-Inflammatory-Pro-Resolving Mediators and Their Receptors	Current Topics in Medicinal Chemistry	2011	234
35	Structure and Function of HIV-1 Integrase	Current Topics in Medicinal Chemistry	2004	231
36	Introduction: P2 Receptors	Current Topics in Medicinal Chemistry	2004	229
37	Review on Epidermal Growth Factor Receptor (EGFR) Structure, Signaling Pathways, Interactions, and Recent Updates of EGFR Inhibitors	Current Topics in Medicinal Chemistry	2020	229
38	The Role of Absorption, Distribution, Metabolism, Excretion and Toxicity in Drug Discovery	Current Topics in Medicinal Chemistry	2003	226
39	Melatonin-mitochondria Interplay in Health and Disease	Current Topics in Medicinal Chemistry	2011	216
40	Magnetic Hyperthermia with Magnetic Nanoparticles: A Status Review	Current Topics in Medicinal Chemistry	2014	216
41	Multidrug Efflux in Pseudomonas aeruginosa Components, Mechanisms and Clinical Significance	Current Topics in Medicinal Chemistry	2001	215
42	Vascularization of Engineered Tissues: Approaches to Promote Angiogenesis in Biomaterials	Current Topics in Medicinal Chemistry	2008	213
43	LncRNA as a Therapeutic Target for Angiogenesis	Current Topics in Medicinal Chemistry	2017	213
44	From Cocaine to Ropivacaine: The History of Local Anesthetic Drugs	Current Topics in Medicinal Chemistry	2001	212
45	Recent Trends in Glycodendrimer Syntheses and Applications	Current Topics in Medicinal Chemistry	2008	212
46	Carbonic Anhydrase Inhibitors as Anticonvulsant Agents	Current Topics in Medicinal Chemistry	2007	209
47	Recent Developments in Azole Compounds as Antibacterial and Antifungal Agents	Current Topics in Medicinal Chemistry	2013	209
48	From Artemisinin to New Artemisinin Antimalarials: Biosynthesis, Extraction, Old and New Derivatives, Stereochemistry and Medicinal Chemistry Requirements	Current Topics in Medicinal Chemistry	2006	208
49	Strategies for Absorption Screening in Drug Discovery and Development	Current Topics in Medicinal Chemistry	2001	207
50	Mapping of the Benzodiazepine Recognition Site on GABA-A Receptors	Current Topics in Medicinal Chemistry	2002	207

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