Current Topics in Medicinal Chemistry

2.3(top 20%)

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4.0K(top 5%)

papers

125.7K(top 5%)

citations

132(top 5%)

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2.4(top 20%)

extended IF

4.7K

all documents

132.7K

doc citations

201(top 5%)

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Top Articles

#	Title	Journal	Year	Citations
1	Toxic Metals and Oxidative Stress Part I: Mechanisms Involved in Me-tal induced Oxidative Damage	Current Topics in Medicinal Chemistry	2001	1,612
2	Sulfur Containing Scaffolds in Drugs: Synthesis and Application in Medicinal Chemistry	Current Topics in Medicinal Chemistry	2016	1,378
3	Chemical and Physical Properties and Potential Mechanisms: Melatonin as a Broad Spectrum Antioxidant and Free Radical Scavenger	Current Topics in Medicinal Chemistry	2002	903
4	Medicinal Chemistry and the Molecular Operating Environment (MOE): Application of QSAR and Molecular Docking to Drug Discovery	Current Topics in Medicinal Chemistry	2008	898
5	Structure-Based Virtual Screening for Drug Discovery: Principles, Applications and Recent Advances	Current Topics in Medicinal Chemistry	2014	746
6	Surface Chemistry Influences Implant Biocompatibility	Current Topics in Medicinal Chemistry	2008	690
7	3D-QSAR in Drug Design - A Review	Current Topics in Medicinal Chemistry	2010	659
8	Physicochemical Profiling (Solubility, Permeability and Charge State)	Current Topics in Medicinal Chemistry	2001	561
9	The Significance of Chirality in Drug Design and Development	Current Topics in Medicinal Chemistry	2011	474
10	Ruthenium Antimetastatic Agents	Current Topics in Medicinal Chemistry	2004	458
11	Oxytosis: A Novel Form of Programmed Cell Death	Current Topics in Medicinal Chemistry	2001	442
12	Melatonin-Immune System Relationships	Current Topics in Medicinal Chemistry	2002	410
13	Peptidylprolyl Cis / Trans Isomerases (Immunophilins): Biological Diversity - Targets - Functions	Current Topics in Medicinal Chemistry	2003	344
14	Antimicrobial Peptide Structure and Mechanism of Action: A Focus on the Role of Membrane Structure	Current Topics in Medicinal Chemistry	2015	342
15	Melatonin as a Chronobiotic / Anticancer Agent: Cellular, Biochemical, and Molecular Mechanisms of Action and their Implications for Circadian-Based Cancer Therapy	Current Topics in Medicinal Chemistry	2002	336
16	Mechanisms of Action of Antiepileptic Drugs	Current Topics in Medicinal Chemistry	2005	332
17	Successful Applications of Computer Aided Drug Discovery: Moving Drugs from Concept to the Clinic	Current Topics in Medicinal Chemistry	2010	308
18	The Biology of p38 Kinase: A Central Role in Inflammation	Current Topics in Medicinal Chemistry	2005	304
19	Quinolones: Action and Resistance Updated	Current Topics in Medicinal Chemistry	2009	298
20	Role of Flavonoids in Oxidative Stress	Current Topics in Medicinal Chemistry	2001	294
21	Trifluoromethyl Ethers and –Thioethers as Tools for Medicinal Chemistry and Drug Discovery	Current Topics in Medicinal Chemistry	2014	293
22	Eicosanoids in Inflammation: Biosynthesis, Pharmacology, and Therapeutic Frontiers	Current Topics in Medicinal Chemistry	2007	281
23	Review on Epidermal Growth Factor Receptor (EGFR) Structure, Signaling Pathways, Interactions, and Recent Updates of EGFR Inhibitors	Current Topics in Medicinal Chemistry	2020	281
24	Medicinal Chemistry and Bioinformatics - Current Trends in Drugs Discovery with Networks Topological Indices	Current Topics in Medicinal Chemistry	2007	276
25	Update on Hsp90 Inhibitors in Clinical Trial	Current Topics in Medicinal Chemistry	2009	273
26	The ATP-Binding Site of Type II Topoisomerases as a Target for Antibacterial Drugs	Current Topics in Medicinal Chemistry	2003	263
27	An Unprecedented Revolution in Medicinal Chemistry Driven by the Progress of Biological Science	Current Topics in Medicinal Chemistry	2017	255
28	Thiazole: A Review on Chemistry, Synthesis and Therapeutic Importance of its Derivatives	Current Topics in Medicinal Chemistry	2016	254
29	Molecular Biology of Serotonin Receptors - Structure and Function at the Molecular Level	Current Topics in Medicinal Chemistry	2002	247
30	The Role of Absorption, Distribution, Metabolism, Excretion and Toxicity in Drug Discovery	Current Topics in Medicinal Chemistry	2003	246
31	Opioid Receptors and their Ligands	Current Topics in Medicinal Chemistry	2004	245
32	Ligand Docking and Structure-based Virtual Screening in Drug Discovery	Current Topics in Medicinal Chemistry	2007	243
33	Estrogen Receptors as Therapeutic Targets in Breast Cancer	Current Topics in Medicinal Chemistry	2006	238
34	Novel Anti-Inflammatory-Pro-Resolving Mediators and Their Receptors	Current Topics in Medicinal Chemistry	2011	237
35	Introduction: P2 Receptors	Current Topics in Medicinal Chemistry	2004	233
36	Molecular Hybridization as a Tool for Designing Multitarget Drug Candidates for Complex Diseases	Current Topics in Medicinal Chemistry	2019	227
37	Magnetic Hyperthermia with Magnetic Nanoparticles: A Status Review	Current Topics in Medicinal Chemistry	2014	223
38	Melatonin-mitochondria Interplay in Health and Disease	Current Topics in Medicinal Chemistry	2011	221
39	Recent Developments in Azole Compounds as Antibacterial and Antifungal Agents	Current Topics in Medicinal Chemistry	2013	221
40	Multidrug Efflux in Pseudomonas aeruginosa Components, Mechanisms and Clinical Significance	Current Topics in Medicinal Chemistry	2001	218
41	LncRNA as a Therapeutic Target for Angiogenesis	Current Topics in Medicinal Chemistry	2017	218
42	From Cocaine to Ropivacaine: The History of Local Anesthetic Drugs	Current Topics in Medicinal Chemistry	2001	216
43	Vascularization of Engineered Tissues: Approaches to Promote Angiogenesis in Biomaterials	Current Topics in Medicinal Chemistry	2008	215
44	Advancements in Docking and Molecular Dynamics Simulations Towards Ligand-receptor Interactions and Structure-function Relationships	Current Topics in Medicinal Chemistry	2018	214
45	Recent Trends in Glycodendrimer Syntheses and Applications	Current Topics in Medicinal Chemistry	2008	213
46	Strategies for Absorption Screening in Drug Discovery and Development	Current Topics in Medicinal Chemistry	2001	211
47	Carbonic Anhydrase Inhibitors as Anticonvulsant Agents	Current Topics in Medicinal Chemistry	2007	211
48	Cephalosporins in Veterinary Medicine - Ceftiofur Use in Food Animals	Current Topics in Medicinal Chemistry	2002	209
49	The Multifactorial Nature of Alzheimer's Disease for Developing Potential Therapeutics	Current Topics in Medicinal Chemistry	2013	209
50	Applications and Toxicity of Silver Nanoparticles: A Recent Review	Current Topics in Medicinal Chemistry	2015	208

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