Applied Immunohistochemistry and Molecular Morphology

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#	Title	Journal	Year	Citations
1	KIT (CD117): A Review on Expression in Normal and Neoplastic Tissues, and Mutations and Their Clinicopathologic Correlation	Applied Immunohistochemistry and Molecular Morphology	2005	449
2	Microsatellite Instability: A Predictive Biomarker for Cancer Immunotherapy	Applied Immunohistochemistry and Molecular Morphology	2018	263
3	Development of a Companion Diagnostic PD-L1 Immunohistochemistry Assay for Pembrolizumab Therapy in Non–Small-cell Lung Cancer	Applied Immunohistochemistry and Molecular Morphology	2016	261
4	Sox10 and S100 in the Diagnosis of Soft-tissue Neoplasms	Applied Immunohistochemistry and Molecular Morphology	2012	250
5	Recommendations for Improved Standardization of Immunohistochemistry	Applied Immunohistochemistry and Molecular Morphology	2007	205
6	Expression of PAX8 in Normal and Neoplastic Tissues	Applied Immunohistochemistry and Molecular Morphology	2011	197
7	Development of an Automated PD-L1 Immunohistochemistry (IHC) Assay for Non–Small Cell Lung Cancer	Applied Immunohistochemistry and Molecular Morphology	2015	171
8	The Diagnostic Value of TTF-1, CK 5/6, and p63 Immunostaining in Classification of Lung Carcinomas	Applied Immunohistochemistry and Molecular Morphology	2007	159
9	Survivin Expression Quantified by Image Pro-plus Compared With Visual Assessment	Applied Immunohistochemistry and Molecular Morphology	2009	158
10	p63 Expression in Lung Carcinoma	Applied Immunohistochemistry and Molecular Morphology	2004	153
11	Localization of Mesothelin in Epithelial Ovarian Cancer	Applied Immunohistochemistry and Molecular Morphology	2005	152
12	Thyroid Transcription Factor-1: A Review	Applied Immunohistochemistry and Molecular Morphology	2002	146
13	Comparison of Thyroid Transcription Factor-1 Expression by 2 Monoclonal Antibodies in Pulmonary and Nonpulmonary Primary Tumors	Applied Immunohistochemistry and Molecular Morphology	2010	145
14	Development of a PD-L1 Complementary Diagnostic Immunohistochemistry Assay (SP142) for Atezolizumab	Applied Immunohistochemistry and Molecular Morphology	2019	144
15	Diagnostic Value of CDX-2 and TTF-1 Expressions in Separating Metastatic Neuroendocrine Neoplasms of Unknown Origin	Applied Immunohistochemistry and Molecular Morphology	2007	139
16	CD79: A Review	Applied Immunohistochemistry and Molecular Morphology	2001	136
17	Paired Comparison of PD-L1 Expression on Cytologic and Histologic Specimens From Malignancies in the Lung Assessed With PD-L1 IHC 28-8pharmDx and PD-L1 IHC 22C3pharmDx	Applied Immunohistochemistry and Molecular Morphology	2017	133
18	SOX10 Expression in Malignant Melanoma, Carcinoma, and Normal Tissues	Applied Immunohistochemistry and Molecular Morphology	2013	124
19	Comparison of Different Antibody Clones for Immunohistochemistry Detection of Programmed Cell Death Ligand 1 (PD-L1) on Non–Small Cell Lung Carcinoma	Applied Immunohistochemistry and Molecular Morphology	2018	124
20	Comparison of Quantification of Histochemical Staining By Hue-Saturation-Intensity (HSI) Transformation and Color-Deconvolution	Applied Immunohistochemistry and Molecular Morphology	2003	123
21	Value of Thyroid Transcription Factor-1 Immunostaining in Tumor Diagnosis	Applied Immunohistochemistry and Molecular Morphology	2012	123
22	Consensus Recommendations on Estrogen Receptor Testing in Breast Cancer By Immunohistochemistry	Applied Immunohistochemistry and Molecular Morphology	2008	118
23	HER2 Expression in Gastric and Gastroesophageal Junction Adenocarcinoma in a US Population	Applied Immunohistochemistry and Molecular Morphology	2012	118
24	Hydroa-Like Cutaneous T-Cell Lymphoma: A Clinicopathologic and Molecular Genetic Study of 16 Pediatric Cases from Peru	Applied Immunohistochemistry and Molecular Morphology	2002	116
25	The Use of Cytokeratin 19 (CK19) Immunohistochemistry in Lesions of the Pancreas, Gastrointestinal Tract, and Liver	Applied Immunohistochemistry and Molecular Morphology	2010	111
26	MGMT Immunohistochemical Expression and Promoter Methylation in Human Glioblastoma	Applied Immunohistochemistry and Molecular Morphology	2008	105
27	Thyroid Transcription Factor-1, Thyroglobulin, Cytokeratin 7, and Cytokeratin 20 in Thyroid Neoplasms	Applied Immunohistochemistry and Molecular Morphology	2000	103
28	Clinicopathologic Characteristics of Microsatellite Instable Gastric Carcinomas Revisited: Urgent Need for Standardization	Applied Immunohistochemistry and Molecular Morphology	2017	103
29	Pathways of Colorectal Carcinogenesis	Applied Immunohistochemistry and Molecular Morphology	2013	100
30	Novel and Classic Myoepithelial/Stem Cell Markers in Metaplastic Carcinomas of the Breast	Applied Immunohistochemistry and Molecular Morphology	2003	99
31	Combination of Napsin A and TTF-1 Immunohistochemistry Helps in Differentiating Primary Lung Adenocarcinoma From Metastatic Carcinoma in the Lung	Applied Immunohistochemistry and Molecular Morphology	2011	99
32	Tissue Microarrays: A Powerful Tool for High-Throughput Analysis of Clinical Specimens	Applied Immunohistochemistry and Molecular Morphology	2002	97
33	Novel Markers of Pancreatic Adenocarcinoma in Fine-Needle Aspiration: Mesothelin and Prostate Stem Cell Antigen Labeling Increases Accuracy in Cytologically Borderline Cases	Applied Immunohistochemistry and Molecular Morphology	2003	95
34	Intratumoral Heterogeneity of Immunohistochemical Marker Expression in Breast Carcinoma	Applied Immunohistochemistry and Molecular Morphology	2010	95
35	Wilms Tumor Gene Product	Applied Immunohistochemistry and Molecular Morphology	2004	93
36	Sox2 Expression in Pulmonary Non-small Cell and Neuroendocrine Carcinomas	Applied Immunohistochemistry and Molecular Morphology	2010	91
37	Standardization of Positive Controls in Diagnostic Immunohistochemistry	Applied Immunohistochemistry and Molecular Morphology	2015	90
38	Determining Tissue of Origin for Metastatic Cancers	Applied Immunohistochemistry and Molecular Morphology	2010	87
39	Diagnostic Utility of Hepatocyte Nuclear Factor 1-Beta Immunoreactivity in Endometrial Carcinomas	Applied Immunohistochemistry and Molecular Morphology	2012	81
40	IHC Optical Density Score: A New Practical Method for Quantitative Immunohistochemistry Image Analysis	Applied Immunohistochemistry and Molecular Morphology	2017	79
41	Immunohistochemical Detection of EWS and FLI-1 Proteins in Ewing Sarcoma and Primitive Neuroectodermal Tumors: Comparative Analysis With CD99 (MIC-2) Expression	Applied Immunohistochemistry and Molecular Morphology	2001	77
42	Anaplastic Large Cell Lymphoma Occurring in Association With Breast Implants	Applied Immunohistochemistry and Molecular Morphology	2013	77
43	erbB-2 (HER-2) and Breast Cancer Progression	Applied Immunohistochemistry and Molecular Morphology	2003	76
44	Systematic Review of HER2 Breast Cancer Testing	Applied Immunohistochemistry and Molecular Morphology	2009	75
45	Prostate Cancer in African American Men Is Associated With Downregulation of Zinc Transporters	Applied Immunohistochemistry and Molecular Morphology	2003	74
46	Estrogen and Progesterone Receptor Expression in Uterine and Extrauterine Leiomyosarcomas	Applied Immunohistochemistry and Molecular Morphology	2004	74
47	Cell Membrane Reactivity of MIB-1 Antibody to Ki67 in Human Tumors: Fact or Artifact?	Applied Immunohistochemistry and Molecular Morphology	2007	74
48	Standardization of Negative Controls in Diagnostic Immunohistochemistry	Applied Immunohistochemistry and Molecular Morphology	2014	74
49	MUM1/IRF4	Applied Immunohistochemistry and Molecular Morphology	2010	73
50	Detecting Gene Rearrangements in Patient Populations Through a 2-Step Diagnostic Test Comprised of Rapid IHC Enrichment Followed by Sensitive Next-Generation Sequencing	Applied Immunohistochemistry and Molecular Morphology	2017	73

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