7.1(top 5%)
impact factor
2.5K(top 10%)
papers
154.3K(top 5%)
citations
175(top 2%)
h-index
7.2(top 5%)
impact factor
3.2K
all documents
169.5K
doc citations
258(top 2%)
g-index

Top Articles

#TitleJournalYearCitations
1The Achilles’ heel of senescent cells: from transcriptome to senolytic drugsAging Cell20151,534
2Senescence-associated β-galactosidase is lysosomal β-galactosidaseAging Cell2006991
3Fat tissue, aging, and cellular senescenceAging Cell2010834
4Lifespan extension by conditions that inhibit translation in Caenorhabditis elegansAging Cell2007784
5Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: the role of PPAR-γ2 transcription factor and TGF-β/BMP signaling pathwaysAging Cell2004718
6Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factorsAging Cell2016717
7Age‐related intrinsic changes in human bone‐marrow‐derived mesenchymal stem cells and their differentiation to osteoblastsAging Cell2008668
8DNA methylation and healthy human agingAging Cell2015665
9SIRT1 transgenic mice show phenotypes resembling calorie restrictionAging Cell2007656
10Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistanceAging Cell2005644
11Calcium and neurodegenerationAging Cell2007643
12SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restrictionAging Cell2007587
13Rapamycin slows aging in miceAging Cell2012580
14DNA damage response and cellular senescence in tissues of aging miceAging Cell2009566
15How sex and age affect immune responses, susceptibility to infections, and response to vaccinationAging Cell2015552
16Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic miceAging Cell2016540
17A senescent cell bystander effect: senescence‐induced senescenceAging Cell2012538
18Long live FOXO: unraveling the role of FOXO proteins in aging and longevityAging Cell2016537
19Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegansAging Cell2009518
20Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longerAging Cell2004505
21Rapamycin‐mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restrictionAging Cell2014486
22Interventions to Slow Aging in Humans: Are We Ready?Aging Cell2015481
23p16INK4Ais a robust in vivo biomarker of cellular aging in human skinAging Cell2006474
24Insulin resistance, oxidative stress, hypertension, and leukocyte telomere length in men from the Framingham Heart StudyAging Cell2006465
25Inhibition of mRNA translation extends lifespan in Caenorhabditis elegansAging Cell2007464
26Oxidative stress and aberrant signaling in aging and cognitive declineAging Cell2007449
27Accelerated epigenetic aging in Down syndromeAging Cell2015446
28Reduced oxygen tension attenuates differentiation capacity of human mesenchymal stem cells and prolongs their lifespanAging Cell2007442
29The chronological life span of Saccharomyces cerevisiaeAging Cell2003437
30Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shorteningAging Cell2010434
31Postmitotic neurons develop a p21‐dependent senescence‐like phenotype driven by a DNA damage responseAging Cell2012434
32Metformin inhibits the senescence‐associated secretory phenotype by interfering with IKK/NF‐κB activationAging Cell2013422
33Aging is associated with chronic innate immune activation and dysregulation of monocyte phenotype and functionAging Cell2012407
34Oxidative stress in the aging substantia nigra and the etiology of Parkinson's diseaseAging Cell2019403
35Targeting senescent cells alleviates obesity‐induced metabolic dysfunctionAging Cell2019395
36Dietary composition specifies consumption, obesity, and lifespan in Drosophila melanogasterAging Cell2008391
37B‐cell diversity decreases in old age and is correlated with poor health statusAging Cell2009386
38Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16Aging Cell2003383
39Expression of p16INK4a in peripheral blood T‐cells is a biomarker of human agingAging Cell2009381
40Innate immunity in aging: impact on macrophage functionAging Cell2004380
41DNA methylation pattern changes upon long‐term culture and aging of human mesenchymal stromal cellsAging Cell2010378
42Tau protein aggregation is associated with cellular senescence in the brainAging Cell2018376
43Blueberry polyphenols increase lifespan and thermotolerance in Caenorhabditis elegansAging Cell2006375
44Calorie restriction mimetics: an emerging research fieldAging Cell2006372
45Age‐related alterations in the dynamic behavior of microgliaAging Cell2011372
46Neurogenesis and aging: FGF-2 and HB-EGF restore neurogenesis in hippocampus and subventricular zone of aged miceAging Cell2003364
47Measuring biological aging in humans: A questAging Cell2020364
48Methylation of ELOVL2 gene as a new epigenetic marker of ageAging Cell2012362
49Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levelsAging Cell2009359
50Mitochondrial function and apoptotic susceptibility in aging skeletal muscleAging Cell2008357