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| 2 | The global epidemiology of hypertension | Nature Reviews Nephrology | 2020 | 2,907 |
| 3 | Glycosylation in health and disease | Nature Reviews Nephrology | 2019 | 1,820 |
| 4 | Genetics of diabetes mellitus and diabetes complications | Nature Reviews Nephrology | 2020 | 1,377 |
| 5 | Cellular and molecular mechanisms of renal fibrosis | Nature Reviews Nephrology | 2011 | 1,283 |
| 6 | Acute kidney disease and renal recovery: consensus report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup | Nature Reviews Nephrology | 2017 | 1,273 |
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| 8 | Mitochondrial energetics in the kidney | Nature Reviews Nephrology | 2017 | 1,121 |
| 9 | Immunoregulatory mechanisms of mesenchymal stem and stromal cells in inflammatory diseases | Nature Reviews Nephrology | 2018 | 1,003 |
| 10 | Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy | Nature Reviews Nephrology | 2011 | 973 |
| 11 | Pre-eclampsia: pathogenesis, novel diagnostics and therapies | Nature Reviews Nephrology | 2019 | 934 |
| 12 | Pre-eclampsia part 1: current understanding of its pathophysiology | Nature Reviews Nephrology | 2014 | 891 |
| 13 | Macrophages: versatile players in renal inflammation and fibrosis | Nature Reviews Nephrology | 2019 | 841 |
| 14 | The immunology of atherosclerosis | Nature Reviews Nephrology | 2017 | 837 |
| 15 | Cellular senescence: the good, the bad and the unknown | Nature Reviews Nephrology | 2022 | 825 |
| 16 | Cellular signalling by primary cilia in development, organ function and disease | Nature Reviews Nephrology | 2019 | 792 |
| 17 | Targeting the progression of chronic kidney disease | Nature Reviews Nephrology | 2020 | 767 |
| 18 | Advances in the understanding and treatment of sepsis-induced immunosuppression | Nature Reviews Nephrology | 2017 | 765 |
| 19 | Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD | Nature Reviews Nephrology | 2015 | 755 |
| 20 | Sex and gender disparities in the epidemiology and outcomes of chronic kidney disease | Nature Reviews Nephrology | 2018 | 731 |
| 21 | Pathophysiology of ischemic acute kidney injury | Nature Reviews Nephrology | 2011 | 706 |
| 22 | Chronic kidney disease and the global public health agenda: an international consensus | Nature Reviews Nephrology | 2024 | 702 |
| 23 | Mechanisms and treatment of organ failure in sepsis | Nature Reviews Nephrology | 2018 | 667 |
| 24 | Acute kidney injury—epidemiology, outcomes and economics | Nature Reviews Nephrology | 2014 | 656 |
| 25 | CKD in diabetes: diabetic kidney disease versus nondiabetic kidney disease | Nature Reviews Nephrology | 2018 | 655 |
| 26 | Inflammatory processes in renal fibrosis | Nature Reviews Nephrology | 2014 | 640 |
| 27 | Obesity-related glomerulopathy: clinical and pathologic characteristics and pathogenesis | Nature Reviews Nephrology | 2016 | 627 |
| 28 | The gut microbiota and the brain–gut–kidney axis in hypertension and chronic kidney disease | Nature Reviews Nephrology | 2018 | 624 |
| 29 | Cardiac surgery-associated acute kidney injury: risk factors, pathophysiology and treatment | Nature Reviews Nephrology | 2017 | 621 |
| 30 | Changing epidemiology of type 2 diabetes mellitus and associated chronic kidney disease | Nature Reviews Nephrology | 2015 | 618 |
| 31 | Glomerular hyperfiltration: definitions, mechanisms and clinical implications | Nature Reviews Nephrology | 2012 | 596 |
| 32 | The Klotho proteins in health and disease | Nature Reviews Nephrology | 2018 | 593 |
| 33 | Heart failure and kidney dysfunction: epidemiology, mechanisms and management | Nature Reviews Nephrology | 2016 | 576 |
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| 35 | COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup | Nature Reviews Nephrology | 2020 | 561 |
| 36 | Single-cell RNA sequencing for the study of development, physiology and disease | Nature Reviews Nephrology | 2018 | 543 |
| 37 | Immunity, endothelial injury and complement-induced coagulopathy in COVID-19 | Nature Reviews Nephrology | 2020 | 536 |
| 38 | Mitochondrial dysfunction in diabetic kidney disease | Nature Reviews Nephrology | 2018 | 530 |
| 39 | Mechanisms of muscle wasting in chronic kidney disease | Nature Reviews Nephrology | 2014 | 526 |
| 40 | Complement in disease: a defence system turning offensive | Nature Reviews Nephrology | 2016 | 517 |
| 41 | Clear cell renal cell carcinoma ontogeny and mechanisms of lethality | Nature Reviews Nephrology | 2020 | 507 |
| 42 | Obesity, kidney dysfunction and hypertension: mechanistic links | Nature Reviews Nephrology | 2019 | 504 |
| 43 | Changes in the worldwide epidemiology of peritoneal dialysis | Nature Reviews Nephrology | 2016 | 484 |
| 44 | Epigenetics and epigenomics in diabetic kidney disease and metabolic memory | Nature Reviews Nephrology | 2019 | 483 |
| 45 | Immune cell dysfunction and inflammation in end-stage renal disease | Nature Reviews Nephrology | 2013 | 480 |
| 46 | Renal, metabolic and cardiovascular considerations of SGLT2 inhibition | Nature Reviews Nephrology | 2016 | 480 |
| 47 | Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies | Nature Reviews Nephrology | 2012 | 477 |
| 48 | The current and future landscape of dialysis | Nature Reviews Nephrology | 2020 | 476 |
| 49 | Epidemiology and risk of cardiovascular disease in populations with chronic kidney disease | Nature Reviews Nephrology | 2022 | 476 |
| 50 | Pathophysiology of diabetic kidney disease: impact of SGLT2 inhibitors | Nature Reviews Nephrology | 2021 | 468 |
