Expert Opinion on Therapeutic Targets

4.5(top 10%)

impact factor

2.0K(top 10%)

papers

73.2K(top 5%)

citations

104(top 5%)

h-index

4.9(top 5%)

impact factor

2.4K

all documents

77.6K

doc citations

147(top 5%)

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Top Articles

#	Title	Journal	Year	Citations
1	Targeting the MAPK–RAS–RAF signaling pathway in cancer therapy	Expert Opinion on Therapeutic Targets	2012	740
2	Targeting the EGFR signaling pathway in cancer therapy	Expert Opinion on Therapeutic Targets	2012	688
3	The RAS/RAF/MEK/ERK and the PI3K/AKT signalling pathways: role in cancer pathogenesis and implications for therapeutic approaches	Expert Opinion on Therapeutic Targets	2012	580
4	Targeting selectins and selectin ligands in inflammation and cancer	Expert Opinion on Therapeutic Targets	2007	323
5	The IL-6/sIL-6R complex as a novel target for therapeutic approaches	Expert Opinion on Therapeutic Targets	2007	314
6	The NF-κB activation pathways, emerging molecular targets for cancer prevention and therapy	Expert Opinion on Therapeutic Targets	2010	314
7	Antidiabetic effects of natural plant extracts via inhibition of carbohydrate hydrolysis enzymes with emphasis on pancreatic alpha amylase	Expert Opinion on Therapeutic Targets	2012	290
8	Cathepsin B as a cancer target	Expert Opinion on Therapeutic Targets	2013	280
9	STAT proteins as novel targets for cancer drug discovery	Expert Opinion on Therapeutic Targets	2004	268
10	Targeting the dopamine D2receptor in schizophrenia	Expert Opinion on Therapeutic Targets	2006	265
11	The paraventricular nucleus of the hypothalamus – a potential target for integrative treatment of autonomic dysfunction	Expert Opinion on Therapeutic Targets	2008	249
12	The role of dopamine in motivation for food in humans: implications for obesity	Expert Opinion on Therapeutic Targets	2002	241
13	MERS-CoV spike protein: a key target for antivirals	Expert Opinion on Therapeutic Targets	2017	236
14	Targeting CCL5 in inflammation	Expert Opinion on Therapeutic Targets	2013	234
15	Extracellular HMGB1 as a therapeutic target in inflammatory diseases	Expert Opinion on Therapeutic Targets	2018	225
16	The 5-HT3receptor as a therapeutic target	Expert Opinion on Therapeutic Targets	2007	217
17	From traditional Ayurvedic medicine to modern medicine: identification of therapeutic targets for suppression of inflammation and cancer	Expert Opinion on Therapeutic Targets	2006	216
18	Targeting the Bcl-2 family for cancer therapy	Expert Opinion on Therapeutic Targets	2013	213
19	Emerging strategies for EphA2 receptor targeting for cancer therapeutics	Expert Opinion on Therapeutic Targets	2011	209
20	Wnt signaling as a therapeutic target for bone diseases	Expert Opinion on Therapeutic Targets	2009	205
21	Tyrosine kinases as targets in cancer therapy – successes and failures	Expert Opinion on Therapeutic Targets	2003	200
22	Inhibiting the transcription factor HSF1 as an anticancer strategy	Expert Opinion on Therapeutic Targets	2009	198
23	The potential of targeting Wnt/β-catenin in colon cancer	Expert Opinion on Therapeutic Targets	2014	198
24	Targeting the HGF/Met signaling pathway in cancer therapy	Expert Opinion on Therapeutic Targets	2012	197
25	Overcoming drug resistance in pancreatic cancer	Expert Opinion on Therapeutic Targets	2011	194
26	Targeting dorsal root ganglia and primary sensory neurons for the treatment of chronic pain	Expert Opinion on Therapeutic Targets	2017	192
27	Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders	Expert Opinion on Therapeutic Targets	2011	187
28	Fatty acid synthase (FASN) as a therapeutic target in breast cancer	Expert Opinion on Therapeutic Targets	2017	185
29	Targeting TGF-β signaling in cancer	Expert Opinion on Therapeutic Targets	2013	183
30	Sulf-2: an extracellular modulator of cell signaling and a cancer target candidate	Expert Opinion on Therapeutic Targets	2010	178
31	Targeting the PI3K signaling pathway in cancer therapy	Expert Opinion on Therapeutic Targets	2012	176
32	Bacterial, fungal and protozoan carbonic anhydrases as drug targets	Expert Opinion on Therapeutic Targets	2015	174
33	CREB, memory enhancement and the treatment of memory disorders: promises, pitfalls and prospects	Expert Opinion on Therapeutic Targets	2003	172
34	Targeting acetylcholinesterase to treat neurodegeneration	Expert Opinion on Therapeutic Targets	2007	172
35	Diabetic nephropathy: an insight into molecular mechanisms and emerging therapies	Expert Opinion on Therapeutic Targets	2019	170
36	Na_v1.7 and other voltage-gated sodium channels as drug targets for pain relief	Expert Opinion on Therapeutic Targets	2016	168
37	Targeting the Wnt/β-catenin signaling pathway in human cancers	Expert Opinion on Therapeutic Targets	2011	164
38	Grb2 signaling in cell motility and cancer	Expert Opinion on Therapeutic Targets	2008	162
39	GLUT1 as a therapeutic target in hepatocellular carcinoma	Expert Opinion on Therapeutic Targets	2009	162
40	Targeting the p53 signaling pathway in cancer therapy – the promises, challenges and perils	Expert Opinion on Therapeutic Targets	2012	162
41	VEGF as a potential target in lung cancer	Expert Opinion on Therapeutic Targets	2017	159
42	Molecular mechanisms of the pro-apoptotic actions of melatonin in cancer: a review	Expert Opinion on Therapeutic Targets	2013	158
43	Targeting the ubiquitin–proteasome system for cancer therapy	Expert Opinion on Therapeutic Targets	2013	157
44	NF-κB as a therapeutic target in neurodegenerative diseases	Expert Opinion on Therapeutic Targets	2007	155
45	Stathmin: a protein with many tasks. New biomarker and potential target in cancer	Expert Opinion on Therapeutic Targets	2011	155
46	Targeting survivin in cancer therapy	Expert Opinion on Therapeutic Targets	2008	154
47	Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery	Expert Opinion on Therapeutic Targets	2007	153
48	Targeting the Nrf2 pathway against cardiovascular disease	Expert Opinion on Therapeutic Targets	2009	153
49	HMGB1, TLR and RAGE: a functional tripod that leads to diabetic inflammation	Expert Opinion on Therapeutic Targets	2011	150
50	TRAIL in cancer therapy: present and future challenges	Expert Opinion on Therapeutic Targets	2007	148

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