4.5(top 10%)
impact factor
1.7K(top 10%)
papers
75.2K(top 5%)
citations
106(top 5%)
h-index
5.0(top 10%)
extended IF
2.5K
all documents
80.9K
doc citations
150(top 5%)
g-index

Top Articles

#TitleJournalYearCitations
1Targeting the MAPK–RAS–RAF signaling pathway in cancer therapyExpert Opinion on Therapeutic Targets2012795
2Targeting the EGFR signaling pathway in cancer therapyExpert Opinion on Therapeutic Targets2012718
3The RAS/RAF/MEK/ERK and the PI3K/AKT signalling pathways: role in cancer pathogenesis and implications for therapeutic approachesExpert Opinion on Therapeutic Targets2012591
4Targeting selectins and selectin ligands in inflammation and cancerExpert Opinion on Therapeutic Targets2007333
5The IL-6/sIL-6R complex as a novel target for therapeutic approachesExpert Opinion on Therapeutic Targets2007321
6Antidiabetic effects of natural plant extracts via inhibition of carbohydrate hydrolysis enzymes with emphasis on pancreatic alpha amylaseExpert Opinion on Therapeutic Targets2012302
7Cathepsin B as a cancer targetExpert Opinion on Therapeutic Targets2013300
8STAT proteins as novel targets for cancer drug discoveryExpert Opinion on Therapeutic Targets2004271
9Targeting the dopamine D2receptor in schizophreniaExpert Opinion on Therapeutic Targets2006268
10The paraventricular nucleus of the hypothalamus – a potential target for integrative treatment of autonomic dysfunctionExpert Opinion on Therapeutic Targets2008262
11Targeting CCL5 in inflammationExpert Opinion on Therapeutic Targets2013258
12MERS-CoV spike protein: a key target for antiviralsExpert Opinion on Therapeutic Targets2017244
13Extracellular HMGB1 as a therapeutic target in inflammatory diseasesExpert Opinion on Therapeutic Targets2018236
14Targeting the Bcl-2 family for cancer therapyExpert Opinion on Therapeutic Targets2013221
15From traditional Ayurvedic medicine to modern medicine: identification of therapeutic targets for suppression of inflammation and cancerExpert Opinion on Therapeutic Targets2006219
16The 5-HT3receptor as a therapeutic targetExpert Opinion on Therapeutic Targets2007217
17The potential of targeting Wnt/β-catenin in colon cancerExpert Opinion on Therapeutic Targets2014205
18Tyrosine kinases as targets in cancer therapy – successes and failuresExpert Opinion on Therapeutic Targets2003204
19Targeting the HGF/Met signaling pathway in cancer therapyExpert Opinion on Therapeutic Targets2012200
20Fatty acid synthase (FASN) as a therapeutic target in breast cancerExpert Opinion on Therapeutic Targets2017200
21Targeting dorsal root ganglia and primary sensory neurons for the treatment of chronic painExpert Opinion on Therapeutic Targets2017199
22Targeting TGF-β signaling in cancerExpert Opinion on Therapeutic Targets2013188
23Diabetic nephropathy: an insight into molecular mechanisms and emerging therapiesExpert Opinion on Therapeutic Targets2019188
24Nav1.7 and other voltage-gated sodium channels as drug targets for pain reliefExpert Opinion on Therapeutic Targets2016181
25Targeting acetylcholinesterase to treat neurodegenerationExpert Opinion on Therapeutic Targets2007180
26Targeting the PI3K signaling pathway in cancer therapyExpert Opinion on Therapeutic Targets2012180
27VEGF as a potential target in lung cancerExpert Opinion on Therapeutic Targets2017177
28CREB, memory enhancement and the treatment of memory disorders: promises, pitfalls and prospectsExpert Opinion on Therapeutic Targets2003176
29Targeting the p53 signaling pathway in cancer therapy – the promises, challenges and perilsExpert Opinion on Therapeutic Targets2012170
30Grb2 signaling in cell motility and cancerExpert Opinion on Therapeutic Targets2008165
31Targeting the ubiquitin–proteasome system for cancer therapyExpert Opinion on Therapeutic Targets2013163
32Molecular mechanisms of the pro-apoptotic actions of melatonin in cancer: a reviewExpert Opinion on Therapeutic Targets2013163
33NF-κB as a therapeutic target in neurodegenerative diseasesExpert Opinion on Therapeutic Targets2007162
34MUC16 as a novel target for cancer therapyExpert Opinion on Therapeutic Targets2018157
35Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discoveryExpert Opinion on Therapeutic Targets2007155
36Targeting survivin in cancer therapyExpert Opinion on Therapeutic Targets2008154
37SIRT1: new avenues of discovery for disorders of oxidative stressExpert Opinion on Therapeutic Targets2012150
38TRAIL in cancer therapy: present and future challengesExpert Opinion on Therapeutic Targets2007148
39Development of ligand-targeted liposomes for cancer therapyExpert Opinion on Therapeutic Targets2004147
40The η-class carbonic anhydrases as drug targets for antimalarial agentsExpert Opinion on Therapeutic Targets2015147
41Brain-derived neurotrophic factor as a driving force behind neuroplasticity in neuropathic and central sensitization pain: a new therapeutic target?Expert Opinion on Therapeutic Targets2015145
42FOXP1: a potential therapeutic target in cancerExpert Opinion on Therapeutic Targets2007144
43Targeting toll-like receptor 4 to modulate neuroinflammation in central nervous system disordersExpert Opinion on Therapeutic Targets2019144
44Targeting IL-1 in depressionExpert Opinion on Therapeutic Targets2012142
45Accelerating Medicines Partnership: Alzheimer’s Disease (AMP-AD) Knowledge Portal Aids Alzheimer’s Drug Discovery through Open Data SharingExpert Opinion on Therapeutic Targets2016142
46Targeting disease through novel pathways of apoptosis and autophagyExpert Opinion on Therapeutic Targets2012141
47The aquaporin-4 water channel as a potential drug target in neurological disordersExpert Opinion on Therapeutic Targets2017140
48Exploring the tumour environment: cancer-associated fibroblasts as targets in cancer therapyExpert Opinion on Therapeutic Targets2005138
49The ERK/MAPK pathway, as a target for the treatment of neuropathic painExpert Opinion on Therapeutic Targets2005138
50Disialoganglioside GD2 as a therapeutic target for human diseasesExpert Opinion on Therapeutic Targets2015136