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Top Articles

#TitleJournalYearCitations
1Molecular dynamics simulations of biomoleculesNature Structural Biology20022,473
2Automated protein model building combined with iterative structure refinementNature Structural Biology19992,328
3Crystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sitesNature Structural Biology19981,201
4A canonical structure for the ligand-binding domain of nuclear receptorsNature Structural Biology1996859
5Inhibition of p38 MAP kinase by utilizing a novel allosteric binding siteNature Structural Biology2002811
6Improved R-factors for diffraction data analysis in macromolecular crystallographyNature Structural Biology1997786
7Crystal structure of a plant catechol oxidase containing a dicopper centerNature Structural Biology1998744
8Identifying conformational changes with site-directed spin labelingNature Structural Biology2000737
9Evolutionarily conserved networks of residues mediate allosteric communication in proteinsNature Structural Biology2003734
10Sequence-dependent mechanics of single DNA moleculesNature Structural Biology1999726
11A gated channel into the proteasome core particleNature Structural Biology2000722
12Designing a 20-residue proteinNature Structural Biology2002716
13Crystal structure of botulinum neurotoxin type A and implications for toxicityNature Structural Biology1998687
14Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active siteNature Structural Biology1999687
15Tunable alignment of macromolecules by filamentous phage yields dipolar coupling interactionsNature Structural Biology1998657
16Crystal structure and assembly of a eukaryotic small heat shock proteinNature Structural Biology2001648
17Structural basis for phosphoserine-proline recognition by group IV WW domainsNature Structural Biology2000644
18Crystal structure of horseradish peroxidase C at 2.15 Å resolutionNature Structural Biology1997642
19Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gatingNature Structural Biology2002605
20Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesisNature Structural Biology1999584
21Structure of human monoamine oxidase B, a drug target for the treatment of neurological disordersNature Structural Biology2002546
22Crystal structure of the outer membrane active transporter FepA from Escherichia coliNature Structural Biology1999531
23Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2Nature Structural Biology1996528
24Rapid, electrostatically assisted association of proteinsNature Structural Biology1996523
25Tubulin and FtsZ form a distinct family of GTPasesNature Structural Biology1998512
26The Protein Data Bank and the challenge of structural genomicsNature Structural Biology2000511
27The crystal structure of Dps, a ferritin homolog that binds and protects DNANature Structural Biology1998490
28Capture of an early fusion-active conformation of HIV-1 gp41Nature Structural Biology1998482
29Crystal structure of the human prion protein reveals a mechanism for oligomerizationNature Structural Biology2001474
30Crystal structure of a nucleosome core particle containing the variant histone H2A.ZNature Structural Biology2000459
31Use of dipolar 1H–15N and 1H–13C couplings in the structure determination of magnetically oriented macromolecules in solutionNature Structural Biology1997456
32The synaptic SNARE complex is a parallel four-stranded helical bundleNature Structural Biology1998450
33Structure of a BRCA1-BARD1 heterodimeric RING-RING complexNature Structural Biology2001446
34Structure of the outer membrane protein A transmembrane domainNature Structural Biology1998445
35Crystal structure of an activated Akt/Protein Kinase B ternary complex with GSK3-peptide and AMP-PNPNature Structural Biology2002443
36The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthaseNature Structural Biology1995442
37The structure of the cytochrome p450BM-3 haem domain complexed with the fatty acid substrate, palmitoleic acidNature Structural Biology1997433
38The structure of the central stalk in bovine F(1)-ATPase at 2.4 A resolutionNature Structural Biology2000427
39Structure of the hepatitis C virus RNA helicase domainNature Structural Biology1997424
40Structure of the DNA binding domain of E. coli SSB bound to ssDNANature Structural Biology2000416
41Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator systemNature Structural Biology2000413
42The barriers in protein foldingNature Structural Biology1994409
43Membrane structure and fusion-triggering conformational change of the fusion domain from influenza hemagglutininNature Structural Biology2001406
44Supramolecular assembly and acid resistance of Helicobacter pylori ureaseNature Structural Biology2001404
45Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservationNature Structural Biology1999397
46The three-dimensional structure of apopain/CPP32, a key mediator of apoptosisNature Structural Biology1996394
47The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemiaNature Structural Biology1999392
48The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificityNature Structural Biology1997387
49Solvent mobility and the protein 'glass' transitionNature Structural Biology2000374
50Kinetic partitioning of protein folding and aggregationNature Structural Biology2002373