| # | Title | Journal | Year | Citations |
|---|
| 1 | Global aetiology and epidemiology of type 2 diabetes mellitus and its complications | Nature Reviews Endocrinology | 2018 | 3,156 |
| 2 | Obesity: global epidemiology and pathogenesis | Nature Reviews Endocrinology | 2019 | 2,603 |
| 3 | Stress and disorders of the stress system | Nature Reviews Endocrinology | 2009 | 2,235 |
| 4 | Muscles, exercise and obesity: skeletal muscle as a secretory organ | Nature Reviews Endocrinology | 2012 | 1,972 |
| 5 | The worldwide epidemiology of type 2 diabetes mellitus—present and future perspectives | Nature Reviews Endocrinology | 2012 | 1,653 |
| 6 | Inflammaging: a new immune–metabolic viewpoint for age-related diseases | Nature Reviews Endocrinology | 2018 | 1,643 |
| 7 | Short-chain fatty acids in control of body weight and insulin sensitivity | Nature Reviews Endocrinology | 2015 | 1,484 |
| 8 | Endometriosis: pathogenesis and treatment | Nature Reviews Endocrinology | 2014 | 1,233 |
| 9 | Polycystic ovary syndrome: etiology, pathogenesis and diagnosis | Nature Reviews Endocrinology | 2011 | 1,062 |
| 10 | Global obesity: trends, risk factors and policy implications | Nature Reviews Endocrinology | 2013 | 1,047 |
| 11 | Polycystic ovary syndrome: definition, aetiology, diagnosis and treatment | Nature Reviews Endocrinology | 2018 | 1,013 |
| 12 | Branched-chain amino acids in metabolic signalling and insulin resistance | Nature Reviews Endocrinology | 2014 | 1,006 |
| 13 | GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus | Nature Reviews Endocrinology | 2012 | 971 |
| 14 | Metformin—mode of action and clinical implications for diabetes and cancer | Nature Reviews Endocrinology | 2014 | 955 |
| 15 | Adipose tissue browning and metabolic health | Nature Reviews Endocrinology | 2014 | 882 |
| 16 | Adapting to obesity with adipose tissue inflammation | Nature Reviews Endocrinology | 2017 | 864 |
| 17 | The role of inflammation in insulitis and β-cell loss in type 1 diabetes | Nature Reviews Endocrinology | 2009 | 847 |
| 18 | Metabolic and cardiovascular adverse effects associated with antipsychotic drugs | Nature Reviews Endocrinology | 2012 | 832 |
| 19 | Gut microbial metabolites in obesity, NAFLD and T2DM | Nature Reviews Endocrinology | 2019 | 817 |
| 20 | Molecular genetics and diagnosis of thyroid cancer | Nature Reviews Endocrinology | 2011 | 798 |
| 21 | Waist circumference as a vital sign in clinical practice: a Consensus Statement from the IAS and ICCR Working Group on Visceral Obesity | Nature Reviews Endocrinology | 2020 | 790 |
| 22 | Global epidemiology of hyperthyroidism and hypothyroidism | Nature Reviews Endocrinology | 2018 | 787 |
| 23 | Regulation of hepatic glucose metabolism in health and disease | Nature Reviews Endocrinology | 2017 | 718 |
| 24 | The G-protein-coupled estrogen receptor GPER in health and disease | Nature Reviews Endocrinology | 2011 | 710 |
| 25 | The changing incidence of thyroid cancer | Nature Reviews Endocrinology | 2016 | 700 |
| 26 | Diabetes mellitus and periodontitis: a tale of two common interrelated diseases | Nature Reviews Endocrinology | 2011 | 698 |
| 27 | SREBP-regulated lipid metabolism: convergent physiology — divergent pathophysiology | Nature Reviews Endocrinology | 2017 | 696 |
| 28 | Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications | Nature Reviews Endocrinology | 2018 | 689 |
| 29 | Effects of poor and short sleep on glucose metabolism and obesity risk | Nature Reviews Endocrinology | 2009 | 688 |
| 30 | Mechanisms of diabetes mellitus-induced bone fragility | Nature Reviews Endocrinology | 2017 | 678 |
| 31 | Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies | Nature Reviews Endocrinology | 2018 | 676 |
| 32 | European Consensus Statement on congenital hypogonadotropic hypogonadism—pathogenesis, diagnosis and treatment | Nature Reviews Endocrinology | 2015 | 664 |
| 33 | Autophagy—a key player in cellular and body metabolism | Nature Reviews Endocrinology | 2014 | 658 |
| 34 | Dyslipidemia in type 2 diabetes mellitus | Nature Reviews Endocrinology | 2009 | 656 |
| 35 | Targeting gut microbiota in obesity: effects of prebiotics and probiotics | Nature Reviews Endocrinology | 2011 | 653 |
| 36 | COVID-19 and diabetes mellitus: from pathophysiology to clinical management | Nature Reviews Endocrinology | 2021 | 653 |
| 37 | The vagus nerve and the inflammatory reflex—linking immunity and metabolism | Nature Reviews Endocrinology | 2012 | 635 |
| 38 | BMP signalling in skeletal development, disease and repair | Nature Reviews Endocrinology | 2016 | 607 |
| 39 | Early-life exposure to EDCs: role in childhood obesity and neurodevelopment | Nature Reviews Endocrinology | 2017 | 601 |
| 40 | Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy | Nature Reviews Endocrinology | 2016 | 597 |
| 41 | Obesity and cancer—mechanisms underlying tumour progression and recurrence | Nature Reviews Endocrinology | 2014 | 575 |
| 42 | Incretin-based therapies for type 2 diabetes mellitus | Nature Reviews Endocrinology | 2009 | 573 |
| 43 | Animal models of obesity and diabetes mellitus | Nature Reviews Endocrinology | 2018 | 563 |
| 44 | New perspectives on osteogenesis imperfecta | Nature Reviews Endocrinology | 2011 | 556 |
| 45 | Epigenetic mechanisms that underpin metabolic and cardiovascular diseases | Nature Reviews Endocrinology | 2009 | 553 |
| 46 | Diabetes mellitus statistics on prevalence and mortality: facts and fallacies | Nature Reviews Endocrinology | 2016 | 544 |
| 47 | Clinical pancreatic islet transplantation | Nature Reviews Endocrinology | 2017 | 525 |
| 48 | Cancer immunotherapy — immune checkpoint blockade and associated endocrinopathies | Nature Reviews Endocrinology | 2017 | 515 |
| 49 | PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD | Nature Reviews Endocrinology | 2017 | 509 |
| 50 | MicroRNA control of bone formation and homeostasis | Nature Reviews Endocrinology | 2012 | 503 |
