| # | Title | Journal | Year | Citations |
|---|
| 1 | The complexity of NF-κB signaling in inflammation and cancer | Molecular Cancer | 2013 | 2,486 |
| 2 | Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma | Molecular Cancer | 2006 | 1,550 |
| 3 | The functional role of long non-coding RNA in human carcinomas | Molecular Cancer | 2011 | 1,450 |
| 4 | CircRNA: functions and properties of a novel potential biomarker for cancer | Molecular Cancer | 2017 | 1,157 |
| 5 | Role of hypoxia in cancer therapy by regulating the tumor microenvironment | Molecular Cancer | 2019 | 1,121 |
| 6 | Targeting PI3K in cancer: mechanisms and advances in clinical trials | Molecular Cancer | 2019 | 940 |
| 7 | Exosomes: composition, biogenesis, and mechanisms in cancer metastasis and drug resistance | Molecular Cancer | 2019 | 853 |
| 8 | Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer | Molecular Cancer | 2014 | 840 |
| 9 | Tumor glycolysis as a target for cancer therapy: progress and prospects | Molecular Cancer | 2013 | 837 |
| 10 | Autophagy and autophagy-related proteins in cancer | Molecular Cancer | 2020 | 815 |
| 11 | Role of the tumor microenvironment in PD-L1/PD-1-mediated tumor immune escape | Molecular Cancer | 2019 | 810 |
| 12 | Functions of N6-methyladenosine and its role in cancer | Molecular Cancer | 2019 | 798 |
| 13 | Kinase-targeted cancer therapies: progress, challenges and future directions | Molecular Cancer | 2018 | 796 |
| 14 | Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma | Molecular Cancer | 2011 | 770 |
| 15 | Circular RNAs function as ceRNAs to regulate and control human cancer progression | Molecular Cancer | 2018 | 757 |
| 16 | Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues | Molecular Cancer | 2006 | 744 |
| 17 | Apoptosis, autophagy, necroptosis, and cancer metastasis | Molecular Cancer | 2015 | 730 |
| 18 | Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4 | Molecular Cancer | 2019 | 723 |
| 19 | The role of m6A RNA methylation in human cancer | Molecular Cancer | 2019 | 714 |
| 20 | m6A regulator-mediated methylation modification patterns and tumor microenvironment infiltration characterization in gastric cancer | Molecular Cancer | 2020 | 704 |
| 21 | Crosstalk between cancer-associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives | Molecular Cancer | 2021 | 702 |
| 22 | The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention | Molecular Cancer | 2007 | 663 |
| 23 | Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies | Molecular Cancer | 2006 | 635 |
| 24 | OncomiRs: the discovery and progress of microRNAs in cancers | Molecular Cancer | 2007 | 619 |
| 25 | The role of necroptosis in cancer biology and therapy | Molecular Cancer | 2019 | 605 |
| 26 | Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells | Molecular Cancer | 2011 | 596 |
| 27 | Mechanisms of receptor tyrosine kinase activation in cancer | Molecular Cancer | 2018 | 580 |
| 28 | Circular RNA circNRIP1 acts as a microRNA-149-5p sponge to promote gastric cancer progression via the AKT1/mTOR pathway | Molecular Cancer | 2019 | 558 |
| 29 | Regulation of epithelial-mesenchymal transition through epigenetic and post-translational modifications | Molecular Cancer | 2016 | 552 |
| 30 | CAF secreted miR-522 suppresses ferroptosis and promotes acquired chemo-resistance in gastric cancer | Molecular Cancer | 2020 | 543 |
| 31 | Biomarkers for predicting efficacy of PD-1/PD-L1 inhibitors | Molecular Cancer | 2018 | 536 |
| 32 | Intra-tumor heterogeneity from a cancer stem cell perspective | Molecular Cancer | 2017 | 533 |
| 33 | Effect of exosomal miRNA on cancer biology and clinical applications | Molecular Cancer | 2018 | 531 |
| 34 | Circular RNA: metabolism, functions and interactions with proteins | Molecular Cancer | 2020 | 526 |
| 35 | The potential role of RNA N6-methyladenosine in Cancer progression | Molecular Cancer | 2020 | 516 |
| 36 | METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma | Molecular Cancer | 2019 | 515 |
| 37 | Mitochondrial defects in cancer | Molecular Cancer | 2002 | 500 |
| 38 | Management of acquired resistance to EGFR TKI–targeted therapy in advanced non-small cell lung cancer | Molecular Cancer | 2018 | 489 |
| 39 | Crosstalk between cancer cells and tumor associated macrophages is required for mesenchymal circulating tumor cell-mediated colorectal cancer metastasis | Molecular Cancer | 2019 | 483 |
| 40 | METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner | Molecular Cancer | 2019 | 475 |
| 41 | ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway | Molecular Cancer | 2017 | 452 |
| 42 | Circular RNA_LARP4 inhibits cell proliferation and invasion of gastric cancer by sponging miR-424-5p and regulating LATS1 expression | Molecular Cancer | 2017 | 449 |
| 43 | CAFs secreted exosomes promote metastasis and chemotherapy resistance by enhancing cell stemness and epithelial-mesenchymal transition in colorectal cancer | Molecular Cancer | 2019 | 449 |
| 44 | mRNA vaccine for cancer immunotherapy | Molecular Cancer | 2021 | 445 |
| 45 | Role of Bruton’s tyrosine kinase in B cells and malignancies | Molecular Cancer | 2018 | 435 |
| 46 | The H19 Long non-coding RNA in cancer initiation, progression and metastasis – a proposed unifying theory | Molecular Cancer | 2015 | 434 |
| 47 | STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4 | Molecular Cancer | 2017 | 434 |
| 48 | The biology of the Ets1 proto-oncogene | Molecular Cancer | 2003 | 427 |
| 49 | Exosomal circRNAs: biogenesis, effect and application in human diseases | Molecular Cancer | 2019 | 424 |
| 50 | Targeting STAT3 in Cancer Immunotherapy | Molecular Cancer | 2020 | 423 |
