# | Title | Journal | Year | Citations |
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1 | THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM | Journal of Clinical Investigation | 1955 | 8,446 |
2 | The basics of epithelial-mesenchymal transition | Journal of Clinical Investigation | 2009 | 8,252 |
3 | Obesity is associated with macrophage accumulation in adipose tissue | Journal of Clinical Investigation | 2003 | 7,111 |
4 | Culture of Human Endothelial Cells Derived from Umbilical Veins. IDENTIFICATION BY MORPHOLOGIC AND IMMUNOLOGIC CRITERIA | Journal of Clinical Investigation | 1973 | 6,420 |
5 | Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance | Journal of Clinical Investigation | 2003 | 4,978 |
6 | Macrophage plasticity and polarization: in vivo veritas | Journal of Clinical Investigation | 2012 | 4,755 |
7 | Obesity is associated with macrophage accumulation in adipose tissue | Journal of Clinical Investigation | 2003 | 4,710 |
8 | Role of AMP-activated protein kinase in mechanism of metformin action | Journal of Clinical Investigation | 2001 | 4,597 |
9 | Increased oxidative stress in obesity and its impact on metabolic syndrome | Journal of Clinical Investigation | 2004 | 4,302 |
10 | Liver fibrosis | Journal of Clinical Investigation | 2005 | 4,210 |
11 | Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies | Journal of Clinical Investigation | 2011 | 4,137 |
12 | Clinical and immunological features of severe and moderate coronavirus disease 2019 | Journal of Clinical Investigation | 2020 | 3,820 |
13 | Obesity induces a phenotypic switch in adipose tissue macrophage polarization | Journal of Clinical Investigation | 2007 | 3,739 |
14 | SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver | Journal of Clinical Investigation | 2002 | 3,528 |
15 | Inflammation and insulin resistance | Journal of Clinical Investigation | 2006 | 3,417 |
16 | A RELATION BETWEEN NON-ESTERIFIED FATTY ACIDS IN PLASMA AND THE METABOLISM OF GLUCOSE | Journal of Clinical Investigation | 1956 | 3,403 |
17 | Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia | Journal of Clinical Investigation | 2003 | 3,356 |
18 | NF-κB: a key role in inflammatory diseases | Journal of Clinical Investigation | 2001 | 3,329 |
19 | An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. | Journal of Clinical Investigation | 1990 | 3,267 |
20 | Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance | Journal of Clinical Investigation | 2003 | 3,195 |
21 | TLR4 links innate immunity and fatty acid–induced insulin resistance | Journal of Clinical Investigation | 2006 | 3,012 |
22 | C-reactive protein: a critical update | Journal of Clinical Investigation | 2003 | 2,941 |
23 | Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. | Journal of Clinical Investigation | 1995 | 2,938 |
24 | Inflammation, stress, and diabetes | Journal of Clinical Investigation | 2005 | 2,822 |
25 | Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. | Journal of Clinical Investigation | 1998 | 2,743 |
26 | Biological Defense Mechanisms. THE PRODUCTION BY LEUKOCYTES OF SUPEROXIDE, A POTENTIAL BACTERICIDAL AGENT | Journal of Clinical Investigation | 1973 | 2,739 |
27 | Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease | Journal of Clinical Investigation | 2005 | 2,731 |
28 | IMMUNOASSAY OF ENDOGENOUS PLASMA INSULIN IN MAN | Journal of Clinical Investigation | 1960 | 2,716 |
29 | Obesity and insulin resistance | Journal of Clinical Investigation | 2000 | 2,600 |
30 | IFN-γ–related mRNA profile predicts clinical response to PD-1 blockade | Journal of Clinical Investigation | 2017 | 2,560 |
31 | Secretory products of macrophages. | Journal of Clinical Investigation | 1987 | 2,470 |
32 | Role of oxidized low density lipoprotein in atherogenesis. | Journal of Clinical Investigation | 1991 | 2,453 |
33 | Mechanisms of fatty acid-induced inhibition of glucose uptake. | Journal of Clinical Investigation | 1994 | 2,370 |
34 | Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome | Journal of Clinical Investigation | 2006 | 2,339 |
35 | Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. | Journal of Clinical Investigation | 1994 | 2,209 |
36 | Cellular mechanisms of insulin resistance | Journal of Clinical Investigation | 2000 | 2,199 |
37 | MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity | Journal of Clinical Investigation | 2006 | 2,190 |
38 | Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. | Journal of Clinical Investigation | 1996 | 2,179 |
39 | SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver | Journal of Clinical Investigation | 2002 | 2,177 |
40 | Sympathetic neural mechanisms in obstructive sleep apnea. | Journal of Clinical Investigation | 1995 | 2,086 |
41 | Wall stress and patterns of hypertrophy in the human left ventricle. | Journal of Clinical Investigation | 1975 | 2,081 |
42 | Endoplasmic reticulum stress: cell life and death decisions | Journal of Clinical Investigation | 2005 | 2,004 |
43 | Safety and antitumor activity of recombinant soluble Apo2 ligand | Journal of Clinical Investigation | 1999 | 1,976 |
44 | Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. | Journal of Clinical Investigation | 1989 | 1,967 |
45 | Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene | Journal of Clinical Investigation | 2003 | 1,957 |
46 | The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. | Journal of Clinical Investigation | 1998 | 1,945 |
47 | Epithelial-mesenchymal transition and its implications for fibrosis | Journal of Clinical Investigation | 2003 | 1,937 |
48 | Biomarkers for epithelial-mesenchymal transitions | Journal of Clinical Investigation | 2009 | 1,907 |
49 | THE NITROUS OXIDE METHOD FOR THE QUANTITATIVE DETERMINATION OF CEREBRAL BLOOD FLOW IN MAN: THEORY, PROCEDURE AND NORMAL VALUES 1 | Journal of Clinical Investigation | 1948 | 1,860 |
50 | Inflammatory links between obesity and metabolic disease | Journal of Clinical Investigation | 2011 | 1,845 |