| # | Title | Journal | Year | Citations |
|---|
| 1 | A global double‐fluorescent Cre reporter mouse | Genesis | 2007 | 2,963 |
| 2 | Cre recombinase: The universal reagent for genome tailoring | Genesis | 2000 | 1,091 |
| 3 | GAL4 system indrosophila: A fly geneticist's swiss army knife | Genesis | 2002 | 923 |
| 4 | Tissue‐specific and inducible Cre‐mediated recombination in the gut epithelium | Genesis | 2004 | 891 |
| 5 | The arabidopsis information resource: Making and mining the “gold standard” annotated reference plant genome | Genesis | 2015 | 884 |
| 6 | Expression of Cre recombinase in the developing mouse limb bud driven by aPrxl enhancer | Genesis | 2002 | 858 |
| 7 | Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon cre-mediated excision | Genesis | 2000 | 790 |
| 8 | Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouse | Genesis | 2003 | 599 |
| 9 | hGFAP-cre transgenic mice for manipulation of glial and neuronal function in vivo | Genesis | 2001 | 570 |
| 10 | Widespread recombinase expression using FLPeR (Flipper) mice | Genesis | 2000 | 564 |
| 11 | Genetic targeting of principal neurons in neocortex and hippocampus of NEX-Cre mice | Genesis | 2006 | 466 |
| 12 | Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision | Genesis | 2000 | 451 |
| 13 | Maternal methyl supplements increase offspring DNA methylation at Axin fused | Genesis | 2006 | 450 |
| 14 | Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells | Genesis | 2006 | 432 |
| 15 | Universal GFP reporter for the study of vascular development | Genesis | 2000 | 424 |
| 16 | Cre recombinase: the universal reagent for genome tailoring | Genesis | 2000 | 416 |
| 17 | Characterization of a mouse strain expressing Cre recombinase from the 3′ untranslated region of the dopamine transporter locus | Genesis | 2006 | 374 |
| 18 | Widespread recombinase expression using FLPeR (flipper) mice | Genesis | 2000 | 363 |
| 19 | Inhibition of zebrafishfgf8 pre-mRNA splicing with morpholino oligos: A quantifiable method for gene knockdown | Genesis | 2001 | 352 |
| 20 | Cre/loxP-mediated inactivation of the murinePten tumor suppressor gene | Genesis | 2002 | 352 |
| 21 | Codon-improved Cre recombinase (iCre) expression in the mouse | Genesis | 2002 | 350 |
| 22 | Col2a1-directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice | Genesis | 2000 | 345 |
| 23 | DNA excision in liver by an albumin-Cre transgene occurs progressively with age | Genesis | 2000 | 339 |
| 24 | Expression of Cre recombinase in mouse oocytes: A means to study maternal effect genes | Genesis | 2000 | 329 |
| 25 | Epiblast-restricted Cre expression in MORE mice: A tool to distinguish embryonic vs. extra-embryonic gene function | Genesis | 2000 | 327 |
| 26 | Consequences of knocking out BMP signaling in the mouse | Genesis | 2003 | 326 |
| 27 | Cre-mediated recombination in cell lineages that express the progesterone receptor | Genesis | 2005 | 316 |
| 28 | From primordial germ cell to primordial follicle: mammalian female germ cell development | Genesis | 2006 | 313 |
| 29 | Inducible lineage tracing of Pax7‐descendant cells reveals embryonic origin of adult satellite cells | Genesis | 2010 | 307 |
| 30 | Generation of a germ cell-specific mouse transgenic Cre line,Vasa-Cre | Genesis | 2007 | 304 |
| 31 | Mouse in red: Red fluorescent protein expression in mouse ES cells, embryos, and adult animals | Genesis | 2004 | 293 |
| 32 | GETDB, a database compiling expression patterns and molecular locations of a collection of gal4 enhancer traps | Genesis | 2002 | 292 |
| 33 | Podocyte‐specific expression of cre recombinase in transgenic mice | Genesis | 2003 | 275 |
| 34 | Embryonic expression of anNkx2-5/Cre gene usingROSA26 reporter mice | Genesis | 2001 | 272 |
| 35 | Conditional inactivation of the TGF-? type II receptor using Cre:Lox | Genesis | 2002 | 267 |
| 36 | Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic mice | Genesis | 2008 | 267 |
| 37 | A CamKIIα iCre BAC allows brain-specific gene inactivation | Genesis | 2001 | 260 |
| 38 | Efficient, inducible Cre‐recombinase activation in vascular endothelium | Genesis | 2008 | 260 |
| 39 | Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line | Genesis | 2001 | 254 |
| 40 | Generation of Pax2-Cre mice by modification of a Pax2 bacterial artificial chromosome | Genesis | 2004 | 253 |
| 41 | Simple and efficient CRISPR/Cas9‐mediated targeted mutagenesis in Xenopus tropicalis | Genesis | 2013 | 251 |
| 42 | Cre recombinase expression in cerebellar Purkinje cells | Genesis | 2000 | 248 |
| 43 | Histone deacetylase activity is required for embryonic stem cell differentiation | Genesis | 2004 | 248 |
| 44 | Generation of a conditional knockout allele for theJanus kinase 2 (Jak2) gene in mice | Genesis | 2004 | 244 |
| 45 | Inducible site-specific recombination in myelinating cells | Genesis | 2003 | 241 |
| 46 | Generation ofBmpr/Alk3 conditional knockout mice | Genesis | 2002 | 239 |
| 47 | A cDNA resource from the basal chordateCiona intestinalis | Genesis | 2002 | 233 |
| 48 | Hepatocyte-specific expression of Cre recombinase | Genesis | 2000 | 229 |
| 49 | Morphant technology in model developmental systems | Genesis | 2001 | 224 |
| 50 | Living synaptic vesicle marker: Synaptotagmin-GFP | Genesis | 2002 | 224 |
