| # | Title | Journal | Year | Citations |
|---|
| 1 | The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic | Nature Reviews Gastroenterology and Hepatology | 2014 | 5,773 |
| 2 | Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention | Nature Reviews Gastroenterology and Hepatology | 2018 | 3,487 |
| 3 | Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics | Nature Reviews Gastroenterology and Hepatology | 2017 | 3,192 |
| 4 | A global view of hepatocellular carcinoma: trends, risk, prevention and management | Nature Reviews Gastroenterology and Hepatology | 2019 | 2,482 |
| 5 | Mechanisms of hepatic stellate cell activation | Nature Reviews Gastroenterology and Hepatology | 2017 | 1,821 |
| 6 | The global burden of IBD: from 2015 to 2025 | Nature Reviews Gastroenterology and Hepatology | 2015 | 1,732 |
| 7 | The role of short-chain fatty acids in microbiota–gut–brain communication | Nature Reviews Gastroenterology and Hepatology | 2019 | 1,519 |
| 8 | The role of the gut microbiota in nutrition and health | Nature Reviews Gastroenterology and Hepatology | 2012 | 1,515 |
| 9 | The global NAFLD epidemic | Nature Reviews Gastroenterology and Hepatology | 2013 | 1,426 |
| 10 | Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies | Nature Reviews Gastroenterology and Hepatology | 2019 | 1,399 |
| 11 | Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis | Nature Reviews Gastroenterology and Hepatology | 2013 | 1,381 |
| 12 | Epidemiology and risk factors for IBD | Nature Reviews Gastroenterology and Hepatology | 2015 | 1,202 |
| 13 | Hepatocellular carcinoma: a global view | Nature Reviews Gastroenterology and Hepatology | 2010 | 1,159 |
| 14 | Cholangiocarcinoma 2020: the next horizon in mechanisms and management | Nature Reviews Gastroenterology and Hepatology | 2020 | 1,155 |
| 15 | The enteric nervous system and neurogastroenterology | Nature Reviews Gastroenterology and Hepatology | 2012 | 1,119 |
| 16 | Immunopathogenesis of IBD: current state of the art | Nature Reviews Gastroenterology and Hepatology | 2016 | 1,107 |
| 17 | Bile acid–microbiota crosstalk in gastrointestinal inflammation and carcinogenesis | Nature Reviews Gastroenterology and Hepatology | 2018 | 1,100 |
| 18 | Gut microbiota and IBD: causation or correlation? | Nature Reviews Gastroenterology and Hepatology | 2017 | 1,099 |
| 19 | NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma | Nature Reviews Gastroenterology and Hepatology | 2011 | 1,049 |
| 20 | Immunotherapy in colorectal cancer: rationale, challenges and potential | Nature Reviews Gastroenterology and Hepatology | 2019 | 1,039 |
| 21 | The gastrointestinal mucus system in health and disease | Nature Reviews Gastroenterology and Hepatology | 2013 | 1,026 |
| 22 | Principles and clinical implications of the brain–gut–enteric microbiota axis | Nature Reviews Gastroenterology and Hepatology | 2009 | 992 |
| 23 | The gut microbiota in IBD | Nature Reviews Gastroenterology and Hepatology | 2012 | 984 |
| 24 | You are what you eat: diet, health and the gut microbiota | Nature Reviews Gastroenterology and Hepatology | 2019 | 980 |
| 25 | Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA) | Nature Reviews Gastroenterology and Hepatology | 2016 | 964 |
| 26 | Probiotics and prebiotics in intestinal health and disease: from biology to the clinic | Nature Reviews Gastroenterology and Hepatology | 2019 | 951 |
| 27 | The gut–liver axis and the intersection with the microbiome | Nature Reviews Gastroenterology and Hepatology | 2018 | 905 |
| 28 | Gut microbiota-derived metabolites as key actors in inflammatory bowel disease | Nature Reviews Gastroenterology and Hepatology | 2020 | 893 |
| 29 | From NASH to HCC: current concepts and future challenges | Nature Reviews Gastroenterology and Hepatology | 2019 | 872 |
| 30 | Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention | Nature Reviews Gastroenterology and Hepatology | 2021 | 867 |
| 31 | NAFLD, NASH and liver cancer | Nature Reviews Gastroenterology and Hepatology | 2013 | 842 |
| 32 | Epidemiology and natural history of HCV infection | Nature Reviews Gastroenterology and Hepatology | 2013 | 833 |
| 33 | The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of synbiotics | Nature Reviews Gastroenterology and Hepatology | 2020 | 826 |
| 34 | Immunology in the liver — from homeostasis to disease | Nature Reviews Gastroenterology and Hepatology | 2016 | 810 |
| 35 | The intestinal epithelial barrier: a therapeutic target? | Nature Reviews Gastroenterology and Hepatology | 2017 | 786 |
| 36 | Serotonin signalling in the gut—functions, dysfunctions and therapeutic targets | Nature Reviews Gastroenterology and Hepatology | 2013 | 784 |
| 37 | Therapeutic developments in pancreatic cancer: current and future perspectives | Nature Reviews Gastroenterology and Hepatology | 2018 | 762 |
| 38 | Diet, microorganisms and their metabolites, and colon cancer | Nature Reviews Gastroenterology and Hepatology | 2016 | 749 |
| 39 | Molecular and cellular mechanisms of liver fibrosis and its regression | Nature Reviews Gastroenterology and Hepatology | 2021 | 746 |
| 40 | The role of the gut microbiota in NAFLD | Nature Reviews Gastroenterology and Hepatology | 2016 | 728 |
| 41 | Probiotics and the gut microbiota in intestinal health and disease | Nature Reviews Gastroenterology and Hepatology | 2010 | 722 |
| 42 | The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics | Nature Reviews Gastroenterology and Hepatology | 2021 | 701 |
| 43 | NAFLD and diabetes mellitus | Nature Reviews Gastroenterology and Hepatology | 2017 | 687 |
| 44 | Gut microbiota in colorectal cancer: mechanisms of action and clinical applications | Nature Reviews Gastroenterology and Hepatology | 2019 | 686 |
| 45 | Towards a more comprehensive concept for prebiotics | Nature Reviews Gastroenterology and Hepatology | 2015 | 679 |
| 46 | Alcoholic liver disease: mechanisms of injury and targeted treatment | Nature Reviews Gastroenterology and Hepatology | 2015 | 643 |
| 47 | Gut microbiota modulation of chemotherapy efficacy and toxicity | Nature Reviews Gastroenterology and Hepatology | 2017 | 643 |
| 48 | Ischaemia–reperfusion injury in liver transplantation—from bench to bedside | Nature Reviews Gastroenterology and Hepatology | 2013 | 633 |
| 49 | The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome | Nature Reviews Gastroenterology and Hepatology | 2010 | 626 |
| 50 | Epidemiology of pancreatic cancer: an overview | Nature Reviews Gastroenterology and Hepatology | 2009 | 614 |
