# | Title | Journal | Year | Citations |
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1 | Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies | Science Translational Medicine | 2014 | 3,665 |
2 | A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β | Science Translational Medicine | 2012 | 3,514 |
3 | Hidden Killers: Human Fungal Infections | Science Translational Medicine | 2012 | 3,368 |
4 | Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors | Science Translational Medicine | 2011 | 2,938 |
5 | The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice | Science Translational Medicine | 2009 | 2,492 |
6 | Wound repair and regeneration: Mechanisms, signaling, and translation | Science Translational Medicine | 2014 | 2,114 |
7 | Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia | Science Translational Medicine | 2014 | 2,069 |
8 | T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia | Science Translational Medicine | 2011 | 2,006 |
9 | PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations | Science Translational Medicine | 2016 | 1,844 |
10 | Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape | Science Translational Medicine | 2012 | 1,837 |
11 | CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia | Science Translational Medicine | 2013 | 1,748 |
12 | The Placenta Harbors a Unique Microbiome | Science Translational Medicine | 2014 | 1,717 |
13 | The gut microbiota influences blood-brain barrier permeability in mice | Science Translational Medicine | 2014 | 1,589 |
14 | Up-Regulation of PD-L1, IDO, and T regs in the Melanoma Tumor Microenvironment Is Driven by CD8 + T Cells | Science Translational Medicine | 2013 | 1,447 |
15 | Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia | Science Translational Medicine | 2015 | 1,402 |
16 | Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses | Science Translational Medicine | 2017 | 1,279 |
17 | Early infancy microbial and metabolic alterations affect risk of childhood asthma | Science Translational Medicine | 2015 | 1,277 |
18 | Temporal Dynamics of the Human Vaginal Microbiota | Science Translational Medicine | 2012 | 1,168 |
19 | Mechanisms of Acquired Crizotinib Resistance in ALK-Rearranged Lung Cancers | Science Translational Medicine | 2012 | 1,138 |
20 | A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma | Science Translational Medicine | 2017 | 1,116 |
21 | Alzheimer’s Disease: The Challenge of the Second Century | Science Translational Medicine | 2011 | 1,109 |
22 | Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA | Science Translational Medicine | 2012 | 1,086 |
23 | Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus | Science Translational Medicine | 2011 | 1,085 |
24 | Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA–Peptide Complexes in Systemic Lupus Erythematosus | Science Translational Medicine | 2011 | 1,080 |
25 | Metabolic Imaging of Patients with Prostate Cancer Using Hyperpolarized [1- 13 C]Pyruvate | Science Translational Medicine | 2013 | 1,061 |
26 | Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer | Science Translational Medicine | 2016 | 1,036 |
27 | NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis | Science Translational Medicine | 2013 | 1,016 |
28 | Antibiotics, birth mode, and diet shape microbiome maturation during early life | Science Translational Medicine | 2016 | 1,012 |
29 | Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile | Science Translational Medicine | 2012 | 978 |
30 | A soft, wearable microfluidic device for the capture, storage, and colorimetric sensing of sweat | Science Translational Medicine | 2016 | 933 |
31 | Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance | Science Translational Medicine | 2011 | 924 |
32 | Inertial Focusing for Tumor Antigen–Dependent and –Independent Sorting of Rare Circulating Tumor Cells | Science Translational Medicine | 2013 | 910 |
33 | Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer | Science Translational Medicine | 2015 | 889 |
34 | An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice | Science Translational Medicine | 2020 | 886 |
35 | Maternal Plasma DNA Sequencing Reveals the Genome-Wide Genetic and Mutational Profile of the Fetus | Science Translational Medicine | 2010 | 878 |
36 | IgA dominates the early neutralizing antibody response to SARS-CoV-2 | Science Translational Medicine | 2021 | 840 |
37 | A Theoretically Based Index of Consciousness Independent of Sensory Processing and Behavior | Science Translational Medicine | 2013 | 839 |
38 | Immunotherapy of non-Hodgkin’s lymphoma with a defined ratio of CD8 + and CD4 + CD19-specific chimeric antigen receptor–modified T cells | Science Translational Medicine | 2016 | 832 |
39 | Conserved Shifts in the Gut Microbiota Due to Gastric Bypass Reduce Host Weight and Adiposity | Science Translational Medicine | 2013 | 824 |
40 | Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer’s disease | Science Translational Medicine | 2016 | 816 |
41 | Direct detection of early-stage cancers using circulating tumor DNA | Science Translational Medicine | 2017 | 808 |
42 | Emtricitabine-Tenofovir Concentrations and Pre-Exposure Prophylaxis Efficacy in Men Who Have Sex with Men | Science Translational Medicine | 2012 | 807 |
43 | Restoring Natural Sensory Feedback in Real-Time Bidirectional Hand Prostheses | Science Translational Medicine | 2014 | 805 |
44 | A Human Disease Model of Drug Toxicity–Induced Pulmonary Edema in a Lung-on-a-Chip Microdevice | Science Translational Medicine | 2012 | 804 |
45 | What does research reproducibility mean? | Science Translational Medicine | 2016 | 804 |
46 | Tracking a Hospital Outbreak of Carbapenem-Resistant Klebsiella pneumoniae with Whole-Genome Sequencing | Science Translational Medicine | 2012 | 781 |
47 | Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis | Science Translational Medicine | 2010 | 774 |
48 | Ultrahigh dose-rate FLASH irradiation increases the differential response between normal and tumor tissue in mice | Science Translational Medicine | 2014 | 768 |
49 | Type 1 diabetes immunotherapy using polyclonal regulatory T cells | Science Translational Medicine | 2015 | 767 |
50 | Natural history of the infant gut microbiome and impact of antibiotic treatment on bacterial strain diversity and stability | Science Translational Medicine | 2016 | 763 |