# | Title | Journal | Year | Citations |
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1 | Inhibitory Effect of di- and Tripeptidyl Aldehydes on Calpains and Cathepsins | Journal of Enzyme Inhibition and Medicinal Chemistry | 1990 | 189 |
2 | Collagenase Inhibitors: Their Design and Potential Therapeutic Use | Journal of Enzyme Inhibition and Medicinal Chemistry | 1987 | 116 |
3 | Inhibitors of HIV-1 Protease | Journal of Enzyme Inhibition and Medicinal Chemistry | 1992 | 115 |
4 | Matrix Metalloproteinase Inhibitors in Arthritis | Journal of Enzyme Inhibition and Medicinal Chemistry | 1998 | 93 |
5 | Xanthine Oxidase Inhibitors from the Leaves ofAlsophila Spinulosa(HOOK) Tryon | Journal of Enzyme Inhibition and Medicinal Chemistry | 1994 | 77 |
6 | Recent Developments in Inhibiting Cysteine and Serine Proteases | Journal of Enzyme Inhibition and Medicinal Chemistry | 1990 | 74 |
7 | Inhibitors of Renin as Potential Therapeutic Agents | Journal of Enzyme Inhibition and Medicinal Chemistry | 1987 | 65 |
8 | Novel Aromatic/Heterocyclic Sulfonamides and Their Metal Complexes as Inhibitors of Carbonic Anhydraseisozymes I, II and IV | Journal of Enzyme Inhibition and Medicinal Chemistry | 1997 | 65 |
9 | Carbonic Anhydrase Inhibitors: Aromatic Sulfonamides and Disulfonamides Act as Efficient Tumor Growth Inhibitors | Journal of Enzyme Inhibition and Medicinal Chemistry | 2000 | 64 |
10 | cDNA Cloning of Human Calpastatin: Sequence Homology Among Human, Pig, and Rabbit Calpastatins | Journal of Enzyme Inhibition and Medicinal Chemistry | 1989 | 57 |
11 | Pyridyl Substituted Benzocycloalkenes: New Inhibitors of 17α-Hydroxylase/ 17,20-Lyase (P450 17α) | Journal of Enzyme Inhibition and Medicinal Chemistry | 1994 | 51 |
12 | Carbonic Anhydrase Inhibitors. Arylsulfonylureido-and Arylureido-Substituted Aromatic and Heterocyclic Sulfonamides: Towards Selective Inhibitors of Carbonic Anhydrase Isozyme I | Journal of Enzyme Inhibition and Medicinal Chemistry | 1999 | 51 |
13 | Cystatin C Based Peptidyl Diazomethanes as Cysteine Proteinase Inhibitors: Influence of the Peptidyl Chain Length | Journal of Enzyme Inhibition and Medicinal Chemistry | 1992 | 49 |
14 | Aromatase Inhibitors in Cigarette Smoke, Tobacco Leaves and Other Plants | Journal of Enzyme Inhibition and Medicinal Chemistry | 1990 | 48 |
15 | Carbonic Anhydrase Inhibitors: Synthesis of Sulfonamides Incorporating 2, 4, 6–Trisubstituted-Pyridinium-Ethylcarboxamido Moieties Possessing Membrane-Impermeability and in Vivo Selectivity for the Membrane-Bound (CA IV) Versus the Cytosolic (CA I and CA II) Isozymes | Journal of Enzyme Inhibition and Medicinal Chemistry | 2000 | 47 |
16 | Dipeptidylpeptidase Iv - Inactivation with N-Peptidyl-O-Aroyl Hydroxylamines | Journal of Enzyme Inhibition and Medicinal Chemistry | 1988 | 46 |
17 | Inhibition of Adenylate Cyclase of Catfish and Rat Hepatocyte Membranes BY 9-(Tetrahydro-2-Furyl)Adenine (SQ 22536) | Journal of Enzyme Inhibition and Medicinal Chemistry | 1991 | 45 |
18 | Inhibition of Gastric H+,K+-ATPase by Flavonoids: A Structure-Activity Study | Journal of Enzyme Inhibition and Medicinal Chemistry | 1999 | 44 |
19 | Inhibition of Glutathione Reductase by Isoproterenol Oxidation Products | Journal of Enzyme Inhibition and Medicinal Chemistry | 1999 | 43 |
20 | The Potential Use of Mechanism-Based Enzyme Inactivators in Medicine | Journal of Enzyme Inhibition and Medicinal Chemistry | 1988 | 42 |
21 | Alkaloidal Sugar Mimetics: Biological Activities and Therapeutic Applications | Journal of Enzyme Inhibition and Medicinal Chemistry | 2000 | 41 |
22 | Sanguinarine and Chelerythrine as Inhibitors of Aromatic Amino Acid Decarboxylase | Journal of Enzyme Inhibition and Medicinal Chemistry | 1996 | 40 |
23 | Interaction of Cystatin C Variants with Papain and Human Cathepsins B, H and L | Journal of Enzyme Inhibition and Medicinal Chemistry | 1999 | 40 |
24 | Measurement of Aromatisation by a Urine Technique Suitable for the Evaluation of Aromatase Inhibitorsin Vivo | Journal of Enzyme Inhibition and Medicinal Chemistry | 1991 | 39 |
25 | Aldose Reductase Inhibitors | Journal of Enzyme Inhibition and Medicinal Chemistry | 2001 | 39 |
26 | Structure and Dynamics of Serine Hydrolase-Organophosphate Adducts | Journal of Enzyme Inhibition and Medicinal Chemistry | 1988 | 38 |
27 | The Effect of Ultrasound on Heme Enzymes in Aqueous Solution | Journal of Enzyme Inhibition and Medicinal Chemistry | 1997 | 38 |
28 | Carbonic Anhydrase Inhibitors. Synthesis of Topically Effective Intraocular Pressure Lowering Agents Derived from 5-(ω-Amino-Alkylcarboxamido)-1,3,4-Thia-Diazole-2-Sulfonamide | Journal of Enzyme Inhibition and Medicinal Chemistry | 1999 | 38 |
29 | Sulfenamido-Sulfonamides as Inhibitors of Carbonic Anhydrase Isozymes I, II And IV | Journal of Enzyme Inhibition and Medicinal Chemistry | 1997 | 37 |
30 | Structure-Activity Relationships for Non-Steroidal Inhibitors of Aromatase | Journal of Enzyme Inhibition and Medicinal Chemistry | 1988 | 36 |
31 | Reactions Between Dipeptidyl Peptidase Iv and Diacyl Hydroxylamines: Mechanistic Investigations | Journal of Enzyme Inhibition and Medicinal Chemistry | 1989 | 35 |
32 | Rational design of selective ligands for trypanothione reductase fromtrypanosoma cruzStructural effects on the inhibition by dibenzazepines based on imipramine | Journal of Enzyme Inhibition and Medicinal Chemistry | 1997 | 35 |
33 | Determination of the Kinetic Parameters for the “Suicide Substrate” Inactivation of Bovine Liver Catalase by Hydrogen Peroxide | Journal of Enzyme Inhibition and Medicinal Chemistry | 1996 | 34 |
34 | Inhibition of Acidic Sphingomyelinase by Xanthone Compounds Isolated fromGarcinia Speciosa | Journal of Enzyme Inhibition and Medicinal Chemistry | 2000 | 34 |
35 | The Mechanism of Binding of Low-Molecular-Weight Active Site Inhibitors to Human α-Thrombin | Journal of Enzyme Inhibition and Medicinal Chemistry | 1998 | 33 |
36 | Novel Small Molecule Nonpeptide Aminopeptidase N Inhibitors with a Cyclic Imide Skeleton | Journal of Enzyme Inhibition and Medicinal Chemistry | 1999 | 33 |
37 | The Interaction of Aspartic Proteinases With Naturally-Occurring Inhibitors From Actinomycetes and Ascaris Lumbricoides | Journal of Enzyme Inhibition and Medicinal Chemistry | 1985 | 32 |
38 | Inhibition of Zinc Metallopeptidases by Flavonoids and Related Phenolic Compounds: Structure-Activity Relationships | Journal of Enzyme Inhibition and Medicinal Chemistry | 1998 | 32 |
39 | Carbonic Anhydrase Inhibitors. Schiff Bases of some Aromatic Sulfonamides and Their Metal Complexes: Towards More Selective Inhibitors of Carbonic Anhydrase Isozyme IV | Journal of Enzyme Inhibition and Medicinal Chemistry | 1999 | 32 |
40 | Carbonic Anhydrase Inhibitors: Inhibition of Isozymes I, II and IV by Sulfamide and Sulfamic Acid Derivatives | Journal of Enzyme Inhibition and Medicinal Chemistry | 2000 | 32 |
41 | Experimental Methods for Kinetic Study of Suicide Substrates | Journal of Enzyme Inhibition and Medicinal Chemistry | 1989 | 31 |
42 | Carbonic Anhydrase Inhibitors. Water-Soluble, Topically Effective Intraocular Pressure Lowering Agents Derived from Isonicotinic Acid and Aromatic/Heterocyclic Sulfonamides: Is the Tail More Important than the Ring? | Journal of Enzyme Inhibition and Medicinal Chemistry | 1999 | 31 |
43 | Kinetic Characterization of Dopamine as a Suicide Substrate of Tyrosinase | Journal of Enzyme Inhibition and Medicinal Chemistry | 1987 | 30 |
44 | Inhibition of Aromatase in Vitro and in Vivo by Aromatase Inhibitors | Journal of Enzyme Inhibition and Medicinal Chemistry | 1990 | 30 |
45 | Molecular Modelling of Lanosterol 14α-Demethylase (CYPSl) fromSaccharomyces Cerevisiaevia Homology with CYP102, a Unique Bacterial Cytochrome P450 Isoform: Quantitative Structure-Activity Relationships (QSARs) within two Related Series of Antifungal Azole Derivatives | Journal of Enzyme Inhibition and Medicinal Chemistry | 1999 | 30 |
46 | Carbonic Anhydrase Activators: Synthesis of High Affinity Isozymes I, II and IV Activators, Derivatives of 4-(4-Tosylureido-Amino Acyl)Ethyl-1H-Imidazole (Histamine Derivatives) | Journal of Enzyme Inhibition and Medicinal Chemistry | 2000 | 30 |
47 | Biochemical and Molecular Aspects of Aromatase | Journal of Enzyme Inhibition and Medicinal Chemistry | 1990 | 29 |
48 | Synthesis and Inhibitory Activity of Acyl-Peptidyl-Pyrrolidine Derivatives Toward Post-Proline Cleaving Enzyme; A Study of Subsite Specificity | Journal of Enzyme Inhibition and Medicinal Chemistry | 1991 | 29 |
49 | Carbonic Anhydrase Inhibitors: Ureido and Thioureido Derivatives of Aromatic Sulfonamides Possessing Increased Affinities for Isozyme I. A Novel Route To 2,5-Disubstituted-L,3,4-Thiadiazoles Via Thioureas, and Their Interaction with Isozymes I, II and IV | Journal of Enzyme Inhibition and Medicinal Chemistry | 1998 | 29 |
50 | Inhibition of Topoisomerases by Fatty Acids | Journal of Enzyme Inhibition and Medicinal Chemistry | 2000 | 29 |