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Top Articles

#TitleJournalYearCitations
1Inhibitory Effect of di- and Tripeptidyl Aldehydes on Calpains and CathepsinsJournal of Enzyme Inhibition and Medicinal Chemistry1990189
2Collagenase Inhibitors: Their Design and Potential Therapeutic UseJournal of Enzyme Inhibition and Medicinal Chemistry1987116
3Inhibitors of HIV-1 ProteaseJournal of Enzyme Inhibition and Medicinal Chemistry1992115
4Matrix Metalloproteinase Inhibitors in ArthritisJournal of Enzyme Inhibition and Medicinal Chemistry199893
5Xanthine Oxidase Inhibitors from the Leaves ofAlsophila Spinulosa(HOOK) TryonJournal of Enzyme Inhibition and Medicinal Chemistry199477
6Recent Developments in Inhibiting Cysteine and Serine ProteasesJournal of Enzyme Inhibition and Medicinal Chemistry199074
7Inhibitors of Renin as Potential Therapeutic AgentsJournal of Enzyme Inhibition and Medicinal Chemistry198765
8Novel Aromatic/Heterocyclic Sulfonamides and Their Metal Complexes as Inhibitors of Carbonic Anhydraseisozymes I, II and IVJournal of Enzyme Inhibition and Medicinal Chemistry199765
9Carbonic Anhydrase Inhibitors: Aromatic Sulfonamides and Disulfonamides Act as Efficient Tumor Growth InhibitorsJournal of Enzyme Inhibition and Medicinal Chemistry200064
10cDNA Cloning of Human Calpastatin: Sequence Homology Among Human, Pig, and Rabbit CalpastatinsJournal of Enzyme Inhibition and Medicinal Chemistry198957
11Pyridyl Substituted Benzocycloalkenes: New Inhibitors of 17α-Hydroxylase/ 17,20-Lyase (P450 17α)Journal of Enzyme Inhibition and Medicinal Chemistry199451
12Carbonic Anhydrase Inhibitors. Arylsulfonylureido-and Arylureido-Substituted Aromatic and Heterocyclic Sulfonamides: Towards Selective Inhibitors of Carbonic Anhydrase Isozyme IJournal of Enzyme Inhibition and Medicinal Chemistry199951
13Cystatin C Based Peptidyl Diazomethanes as Cysteine Proteinase Inhibitors: Influence of the Peptidyl Chain LengthJournal of Enzyme Inhibition and Medicinal Chemistry199249
14Aromatase Inhibitors in Cigarette Smoke, Tobacco Leaves and Other PlantsJournal of Enzyme Inhibition and Medicinal Chemistry199048
15Carbonic Anhydrase Inhibitors: Synthesis of Sulfonamides Incorporating 2, 4, 6–Trisubstituted-Pyridinium-Ethylcarboxamido Moieties Possessing Membrane-Impermeability and in Vivo Selectivity for the Membrane-Bound (CA IV) Versus the Cytosolic (CA I and CA II) IsozymesJournal of Enzyme Inhibition and Medicinal Chemistry200047
16Dipeptidylpeptidase Iv - Inactivation with N-Peptidyl-O-Aroyl HydroxylaminesJournal of Enzyme Inhibition and Medicinal Chemistry198846
17Inhibition of Adenylate Cyclase of Catfish and Rat Hepatocyte Membranes BY 9-(Tetrahydro-2-Furyl)Adenine (SQ 22536)Journal of Enzyme Inhibition and Medicinal Chemistry199145
18Inhibition of Gastric H+,K+-ATPase by Flavonoids: A Structure-Activity StudyJournal of Enzyme Inhibition and Medicinal Chemistry199944
19Inhibition of Glutathione Reductase by Isoproterenol Oxidation ProductsJournal of Enzyme Inhibition and Medicinal Chemistry199943
20The Potential Use of Mechanism-Based Enzyme Inactivators in MedicineJournal of Enzyme Inhibition and Medicinal Chemistry198842
21Alkaloidal Sugar Mimetics: Biological Activities and Therapeutic ApplicationsJournal of Enzyme Inhibition and Medicinal Chemistry200041
22Sanguinarine and Chelerythrine as Inhibitors of Aromatic Amino Acid DecarboxylaseJournal of Enzyme Inhibition and Medicinal Chemistry199640
23Interaction of Cystatin C Variants with Papain and Human Cathepsins B, H and LJournal of Enzyme Inhibition and Medicinal Chemistry199940
24Measurement of Aromatisation by a Urine Technique Suitable for the Evaluation of Aromatase Inhibitorsin VivoJournal of Enzyme Inhibition and Medicinal Chemistry199139
25Aldose Reductase InhibitorsJournal of Enzyme Inhibition and Medicinal Chemistry200139
26Structure and Dynamics of Serine Hydrolase-Organophosphate AdductsJournal of Enzyme Inhibition and Medicinal Chemistry198838
27The Effect of Ultrasound on Heme Enzymes in Aqueous SolutionJournal of Enzyme Inhibition and Medicinal Chemistry199738
28Carbonic Anhydrase Inhibitors. Synthesis of Topically Effective Intraocular Pressure Lowering Agents Derived from 5-(ω-Amino-Alkylcarboxamido)-1,3,4-Thia-Diazole-2-SulfonamideJournal of Enzyme Inhibition and Medicinal Chemistry199938
29Sulfenamido-Sulfonamides as Inhibitors of Carbonic Anhydrase Isozymes I, II And IVJournal of Enzyme Inhibition and Medicinal Chemistry199737
30Structure-Activity Relationships for Non-Steroidal Inhibitors of AromataseJournal of Enzyme Inhibition and Medicinal Chemistry198836
31Reactions Between Dipeptidyl Peptidase Iv and Diacyl Hydroxylamines: Mechanistic InvestigationsJournal of Enzyme Inhibition and Medicinal Chemistry198935
32Rational design of selective ligands for trypanothione reductase fromtrypanosoma cruzStructural effects on the inhibition by dibenzazepines based on imipramineJournal of Enzyme Inhibition and Medicinal Chemistry199735
33Determination of the Kinetic Parameters for the “Suicide Substrate” Inactivation of Bovine Liver Catalase by Hydrogen PeroxideJournal of Enzyme Inhibition and Medicinal Chemistry199634
34Inhibition of Acidic Sphingomyelinase by Xanthone Compounds Isolated fromGarcinia SpeciosaJournal of Enzyme Inhibition and Medicinal Chemistry200034
35The Mechanism of Binding of Low-Molecular-Weight Active Site Inhibitors to Human α-ThrombinJournal of Enzyme Inhibition and Medicinal Chemistry199833
36Novel Small Molecule Nonpeptide Aminopeptidase N Inhibitors with a Cyclic Imide SkeletonJournal of Enzyme Inhibition and Medicinal Chemistry199933
37The Interaction of Aspartic Proteinases With Naturally-Occurring Inhibitors From Actinomycetes and Ascaris LumbricoidesJournal of Enzyme Inhibition and Medicinal Chemistry198532
38Inhibition of Zinc Metallopeptidases by Flavonoids and Related Phenolic Compounds: Structure-Activity RelationshipsJournal of Enzyme Inhibition and Medicinal Chemistry199832
39Carbonic Anhydrase Inhibitors. Schiff Bases of some Aromatic Sulfonamides and Their Metal Complexes: Towards More Selective Inhibitors of Carbonic Anhydrase Isozyme IVJournal of Enzyme Inhibition and Medicinal Chemistry199932
40Carbonic Anhydrase Inhibitors: Inhibition of Isozymes I, II and IV by Sulfamide and Sulfamic Acid DerivativesJournal of Enzyme Inhibition and Medicinal Chemistry200032
41Experimental Methods for Kinetic Study of Suicide SubstratesJournal of Enzyme Inhibition and Medicinal Chemistry198931
42Carbonic Anhydrase Inhibitors. Water-Soluble, Topically Effective Intraocular Pressure Lowering Agents Derived from Isonicotinic Acid and Aromatic/Heterocyclic Sulfonamides: Is the Tail More Important than the Ring?Journal of Enzyme Inhibition and Medicinal Chemistry199931
43Kinetic Characterization of Dopamine as a Suicide Substrate of TyrosinaseJournal of Enzyme Inhibition and Medicinal Chemistry198730
44Inhibition of Aromatase in Vitro and in Vivo by Aromatase InhibitorsJournal of Enzyme Inhibition and Medicinal Chemistry199030
45Molecular Modelling of Lanosterol 14α-Demethylase (CYPSl) fromSaccharomyces Cerevisiaevia Homology with CYP102, a Unique Bacterial Cytochrome P450 Isoform: Quantitative Structure-Activity Relationships (QSARs) within two Related Series of Antifungal Azole DerivativesJournal of Enzyme Inhibition and Medicinal Chemistry199930
46Carbonic Anhydrase Activators: Synthesis of High Affinity Isozymes I, II and IV Activators, Derivatives of 4-(4-Tosylureido-Amino Acyl)Ethyl-1H-Imidazole (Histamine Derivatives)Journal of Enzyme Inhibition and Medicinal Chemistry200030
47Biochemical and Molecular Aspects of AromataseJournal of Enzyme Inhibition and Medicinal Chemistry199029
48Synthesis and Inhibitory Activity of Acyl-Peptidyl-Pyrrolidine Derivatives Toward Post-Proline Cleaving Enzyme; A Study of Subsite SpecificityJournal of Enzyme Inhibition and Medicinal Chemistry199129
49Carbonic Anhydrase Inhibitors: Ureido and Thioureido Derivatives of Aromatic Sulfonamides Possessing Increased Affinities for Isozyme I. A Novel Route To 2,5-Disubstituted-L,3,4-Thiadiazoles Via Thioureas, and Their Interaction with Isozymes I, II and IVJournal of Enzyme Inhibition and Medicinal Chemistry199829
50Inhibition of Topoisomerases by Fatty AcidsJournal of Enzyme Inhibition and Medicinal Chemistry200029