| # | Title | Journal | Year | Citations |
|---|
| 1 | Random-effects model for meta-analysis of clinical trials: An update | Contemporary Clinical Trials | 2007 | 1,801 |
| 2 | Meta-analysis in clinical trials revisited | Contemporary Clinical Trials | 2015 | 1,745 |
| 3 | Design and analysis of stepped wedge cluster randomized trials | Contemporary Clinical Trials | 2007 | 1,010 |
| 4 | Design and baseline characteristics of the osteoporotic fractures in men (MrOS) study — A large observational study of the determinants of fracture in older men | Contemporary Clinical Trials | 2005 | 670 |
| 5 | Overview of recruitment for the osteoporotic fractures in men study (MrOS) | Contemporary Clinical Trials | 2005 | 506 |
| 6 | The VITamin D and OmegA-3 TriaL (VITAL): Rationale and design of a large randomized controlled trial of vitamin D and marine omega-3 fatty acid supplements for the primary prevention of cancer and cardiovascular disease | Contemporary Clinical Trials | 2012 | 477 |
| 7 | Advances in the meta-analysis of heterogeneous clinical trials I: The inverse variance heterogeneity model | Contemporary Clinical Trials | 2015 | 440 |
| 8 | The use of unequal randomisation ratios in clinical trials: A review | Contemporary Clinical Trials | 2006 | 269 |
| 9 | Pharmaceutical company funding and its consequences: A qualitative systematic review | Contemporary Clinical Trials | 2008 | 253 |
| 10 | The quality of randomized trial reporting in leading medical journals since the revised CONSORT statement | Contemporary Clinical Trials | 2005 | 226 |
| 11 | The effectiveness and ineffectiveness of complex behavioral interventions: Impact of treatment fidelity | Contemporary Clinical Trials | 2014 | 215 |
| 12 | Study design of ASPirin in Reducing Events in the Elderly (ASPREE): A randomized, controlled trial | Contemporary Clinical Trials | 2013 | 212 |
| 13 | Are propensity scores really superior to standard multivariable analysis? | Contemporary Clinical Trials | 2011 | 206 |
| 14 | Strategies addressing barriers to clinical trial enrollment of underrepresented populations: A systematic review | Contemporary Clinical Trials | 2014 | 206 |
| 15 | TIMI, GRACE and alternative risk scores in Acute Coronary Syndromes: A meta-analysis of 40 derivation studies on 216,552 patients and of 42 validation studies on 31,625 patients | Contemporary Clinical Trials | 2012 | 190 |
| 16 | Clinical trials recruitment planning: A proposed framework from the Clinical Trials Transformation Initiative | Contemporary Clinical Trials | 2018 | 186 |
| 17 | Comparison of methods for estimating the intraclass correlation coefficient for binary responses in cancer prevention cluster randomized trials | Contemporary Clinical Trials | 2012 | 184 |
| 18 | Efficacy and safety study of cenicriviroc for the treatment of non-alcoholic steatohepatitis in adult subjects with liver fibrosis: CENTAUR Phase 2b study design | Contemporary Clinical Trials | 2016 | 178 |
| 19 | Advances in the meta-analysis of heterogeneous clinical trials II: The quality effects model | Contemporary Clinical Trials | 2015 | 171 |
| 20 | Design of the Trial of Activity in Adolescent Girls (TAAG) | Contemporary Clinical Trials | 2005 | 167 |
| 21 | The Ginkgo Evaluation of Memory (GEM) study: Design and baseline data of a randomized trial of Ginkgo biloba extract in prevention of dementia | Contemporary Clinical Trials | 2006 | 164 |
| 22 | Recruitment of minority and underserved populations in the United States: The centers for population health and health disparities experience | Contemporary Clinical Trials | 2008 | 164 |
| 23 | Inclusion of patient-reported outcome measures in registered clinical trials: Evidence from ClinicalTrials.gov (2007–2013) | Contemporary Clinical Trials | 2015 | 162 |
| 24 | A systematic review of the factors influencing African Americans' participation in cancer clinical trials | Contemporary Clinical Trials | 2013 | 160 |
| 25 | More than the money: A review of the literature examining healthy volunteer motivations | Contemporary Clinical Trials | 2011 | 154 |
| 26 | Can regional analgesia reduce the risk of recurrence after breast cancer? | Contemporary Clinical Trials | 2008 | 149 |
| 27 | The Prostate cancer Intervention Versus Observation Trial:VA/NCI/AHRQ Cooperative Studies Program #407 (PIVOT): Design and baseline results of a randomized controlled trial comparing radical prostatectomy to watchful waiting for men with clinically localized prostate cancer | Contemporary Clinical Trials | 2009 | 146 |
| 28 | Performance of five two-sample location tests for skewed distributions with unequal variances | Contemporary Clinical Trials | 2009 | 141 |
| 29 | Pioglitazone versus vitamin E versus placebo for the treatment of non-diabetic patients with non-alcoholic steatohepatitis: PIVENS trial design | Contemporary Clinical Trials | 2009 | 140 |
| 30 | The Vitamin D Antenatal Asthma Reduction Trial (VDAART): Rationale, design, and methods of a randomized, controlled trial of vitamin D supplementation in pregnancy for the primary prevention of asthma and allergies in children | Contemporary Clinical Trials | 2014 | 139 |
| 31 | Pilot and feasibility studies: Is there a difference from each other and from a randomised controlled trial? | Contemporary Clinical Trials | 2014 | 139 |
| 32 | Recruitment and retention strategies in longitudinal clinical studies with low-income populations | Contemporary Clinical Trials | 2011 | 137 |
| 33 | The lifestyle interventions and independence for elders (LIFE) pilot study: Design and methods | Contemporary Clinical Trials | 2005 | 129 |
| 34 | ADD-ASPIRIN: A phase III, double-blind, placebo controlled, randomised trial assessing the effects of aspirin on disease recurrence and survival after primary therapy in common non-metastatic solid tumours | Contemporary Clinical Trials | 2016 | 129 |
| 35 | Reporting of harms in randomized controlled trials of psychological interventions for mental and behavioral disorders: A review of current practice | Contemporary Clinical Trials | 2014 | 127 |
| 36 | Review of randomised trials using the post-randomised consent (Zelen's) design | Contemporary Clinical Trials | 2006 | 125 |
| 37 | Detecting a clinically meaningful change in tic severity in Tourette syndrome: A comparison of three methods | Contemporary Clinical Trials | 2013 | 124 |
| 38 | Using e-technologies in clinical trials | Contemporary Clinical Trials | 2015 | 124 |
| 39 | Using instrumented paper diaries to document self-monitoring patterns in weight loss | Contemporary Clinical Trials | 2008 | 122 |
| 40 | The use of patient-reported outcomes instruments in registered clinical trials: Evidence from ClinicalTrials.gov | Contemporary Clinical Trials | 2009 | 122 |
| 41 | Overfitting in prediction models – Is it a problem only in high dimensions? | Contemporary Clinical Trials | 2013 | 122 |
| 42 | Do “placebo responders” exist? | Contemporary Clinical Trials | 2008 | 118 |
| 43 | Physical activity and lymphedema (the PAL trial): Assessing the safety of progressive strength training in breast cancer survivors | Contemporary Clinical Trials | 2009 | 116 |
| 44 | Recruitment and retention strategies in clinical studies with low-income and minority populations: Progress from 2004–2014 | Contemporary Clinical Trials | 2015 | 115 |
| 45 | Wearable activity monitors in oncology trials: Current use of an emerging technology | Contemporary Clinical Trials | 2018 | 115 |
| 46 | An analysis of U.S. practices of paying research participants | Contemporary Clinical Trials | 2005 | 113 |
| 47 | Comparison of paper-based and electronic data collection process in clinical trials: Costs simulation study | Contemporary Clinical Trials | 2009 | 113 |
| 48 | Early anti-pseudomonal acquisition in young patients with cystic fibrosis: Rationale and design of the EPIC clinical trial and observational study, | Contemporary Clinical Trials | 2009 | 110 |
| 49 | SMART trial: A randomized clinical trial of self-monitoring in behavioral weight management-design and baseline findings | Contemporary Clinical Trials | 2009 | 109 |
| 50 | The CALERIE Study: Design and methods of an innovative 25% caloric restriction intervention | Contemporary Clinical Trials | 2011 | 109 |
