| # | Title | Journal | Year | Citations |
|---|
| 1 | Molecular cloning and characterization of a novel DNA virus (TTV) associated with posttransfusion hepatitis of unknown etiology | Hepatology Research | 1998 | 541 |
| 2 | Japan Society of Hepatology guidelines for sarcopenia in liver disease (1st edition): Recommendation from the working group for creation of sarcopenia assessment criteria | Hepatology Research | 2016 | 463 |
| 3 | Clinical practice guidelines for hepatocellular carcinoma: The Japan Society of Hepatology 2017 (4th JSH‐HCC guidelines) 2019 update | Hepatology Research | 2019 | 399 |
| 4 | Report of the 17th Nationwide Follow‐up Survey of Primary Liver Cancer in Japan† | Hepatology Research | 2007 | 376 |
| 5 | Evidence‐based Clinical Practice Guidelines for Hepatocellular Carcinoma: The Japan Society of Hepatology 2013 update (3rd JSH‐HCC Guidelines) | Hepatology Research | 2015 | 339 |
| 6 | Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: Association with MMP‐9 | Hepatology Research | 2009 | 308 |
| 7 | Epidemiology of hepatocellular carcinoma in USA | Hepatology Research | 2007 | 283 |
| 8 | Development of evidence‐based clinical guidelines for the diagnosis and treatment of hepatocellular carcinoma in Japan | Hepatology Research | 2008 | 279 |
| 9 | Very high prevalence of TT virus (TTV) infection in general population of Japan revealed by a new set of PCR primers | Hepatology Research | 1998 | 260 |
| 10 | Epidemiology of hepatitis B virus in Africa, its genotypes and clinical associations of genotypes | Hepatology Research | 2007 | 257 |
| 11 | Liver X receptor in cooperation with SREBP‐1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease | Hepatology Research | 2008 | 230 |
| 12 | Connective tissue growth factor (CTGF/CCN2) in hepatic fibrosis | Hepatology Research | 2003 | 213 |
| 13 | Longitudinal analysis of murine steatohepatitis model induced by chronic exposure to high‐fat diet | Hepatology Research | 2007 | 196 |
| 14 | Portal vein invasion and intrahepatic micrometastasis in small hepatocellular carcinoma by gross type | Hepatology Research | 2003 | 193 |
| 15 | Geographical and genetic diversity of the human hepatitis B virus | Hepatology Research | 2010 | 190 |
| 16 | Alterations of DNA methylation and histone modifications contribute to gene silencing in hepatocellular carcinomas | Hepatology Research | 2007 | 185 |
| 17 | Oxidative stress and liver disease | Hepatology Research | 2012 | 185 |
| 18 | Persistent infection of hepatitis E virus transmitted by blood transfusion in a patient with T‐cell lymphoma | Hepatology Research | 2007 | 183 |
| 19 | Efficacy of lamivudine for preventing hepatocellular carcinoma in chronic hepatitis B: A multicenter retrospective study of 2795 patients | Hepatology Research | 2005 | 180 |
| 20 | Assessment of liver function for safe hepatic resection | Hepatology Research | 2009 | 180 |
| 21 | Overweight and obesity increase the risk for liver cancer in patients with liver cirrhosis and long-term oral supplementation with branched-chain amino acid granules inhibits liver carcinogenesis in heavier patients with liver cirrhosis | Hepatology Research | 2006 | 179 |
| 22 | Role of sorafenib in the treatment of advanced hepatocellular carcinoma: An update | Hepatology Research | 2013 | 173 |
| 23 | Liver and diabetes. A vicious circle | Hepatology Research | 2013 | 166 |
| 24 | Comparison of FIB‐4 index, NAFLD fibrosis score and BARD score for prediction of advanced fibrosis in adult patients with non‐alcoholic fatty liver disease: A meta‐analysis study | Hepatology Research | 2016 | 165 |
| 25 | Regulatory processes interacting to maintain hepatic blood flow constancy: Vascular compliance, hepatic arterial buffer response, hepatorenal reflex, liver regeneration, escape from vasoconstriction | Hepatology Research | 2007 | 155 |
| 26 | Management of hepatocellular carcinoma: Report of Consensus Meeting in the 45th Annual Meeting of the Japan Society of Hepatology (2009) | Hepatology Research | 2010 | 154 |
| 27 | Evidence‐based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis | Hepatology Research | 2015 | 149 |
| 28 | Report of the 15th follow-up survey of primary liver cancer | Hepatology Research | 2004 | 148 |
| 29 | Pilot study of liraglutide effects in non‐alcoholic steatohepatitis and non‐alcoholic fatty liver disease with glucose intolerance in Japanese patients (LEAN‐J) | Hepatology Research | 2015 | 148 |
| 30 | Bead‐based microarray analysis of microRNA expression in hepatocellular carcinoma: miR‐338 is downregulated | Hepatology Research | 2009 | 144 |
| 31 | JSH Guidelines for the Management of Hepatitis B Virus Infection | Hepatology Research | 2014 | 142 |
| 32 | Abnormality of autophagic function and cathepsin expression in the liver from patients with non‐alcoholic fatty liver disease | Hepatology Research | 2014 | 140 |
| 33 | CYP2E1: from ASH to NASH | Hepatology Research | 2004 | 139 |
| 34 | A prospective study of acute drug-induced liver injury in patients suffering from non-alcoholic fatty liver disease | Hepatology Research | 2007 | 139 |
| 35 | Fulminant hepatitis and late onset hepatic failure in Japan | Hepatology Research | 2008 | 138 |
| 36 | Rapid skeletal muscle wasting predicts worse survival in patients with liver cirrhosis | Hepatology Research | 2016 | 138 |
| 37 | Hepatitis E virus infection in wild mongooses of Okinawa, Japan: Demonstration of anti-HEV antibodies and a full-genome nucleotide sequence☆ | Hepatology Research | 2006 | 137 |
| 38 | Analysis of hepatic genes involved in the metabolism of fatty acids and iron in nonalcoholic fatty liver disease | Hepatology Research | 2009 | 137 |
| 39 | NASH: A global health problem | Hepatology Research | 2011 | 136 |
| 40 | Lessons from animal models of NASH | Hepatology Research | 2005 | 135 |
| 41 | Response Evaluation Criteria in Cancer of the Liver (RECICL) proposed by the Liver Cancer Study Group of Japan (2009 Revised Version) | Hepatology Research | 2010 | 130 |
| 42 | Acute hepatitis E of a man who consumed wild boar meat prior to the onset of illness in Nagasaki, Japan | Hepatology Research | 2005 | 129 |
| 43 | Tolvaptan for improvement of hepatic edema: A phase 3, multicenter, randomized, double‐blind, placebo‐controlled trial | Hepatology Research | 2014 | 128 |
| 44 | Report of the 16th follow-up survey of primary liver cancer | Hepatology Research | 2005 | 125 |
| 45 | Report of the 19th follow‐up survey of primary liver cancer in Japan | Hepatology Research | 2016 | 125 |
| 46 | The independent predictors of non‐alcoholic steatohepatitis and its individual histological features. | Hepatology Research | 2016 | 124 |
| 47 | The efficacy of ursodeoxycholic acid and bezafibrate combination therapy for primary biliary cirrhosis: A prospective, multicenter study | Hepatology Research | 2008 | 123 |
| 48 | Liver injury is associated with severe coronavirus disease 2019 (COVID‐19) infection: A systematic review and meta‐analysis of retrospective studies | Hepatology Research | 2020 | 122 |
| 49 | Prognostic performance of the new classification of primary liver cancer of Japan (4th edition) for patients with hepatocellular carcinoma: a validation analysis | Hepatology Research | 2002 | 121 |
| 50 | Over-expression of c-raf-1 proto-oncogene in liver cirrhosis and hepatocellular carcinoma*1 | Hepatology Research | 2004 | 121 |
