Medicinal Chemistry Research

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Top Articles

#	Title	Journal	Year	Citations
1	Coumarin: a potential nucleus for anti-inflammatory molecules	Medicinal Chemistry Research	2013	232
2	Development of drugs based on imidazole and benzimidazole bioactive heterocycles: recent advances and future directions	Medicinal Chemistry Research	2016	220
3	Hydrazide–hydrazones as potential antimicrobial agents: overview of the literature since 2010	Medicinal Chemistry Research	2017	197
4	Thiazoles: having diverse biological activities	Medicinal Chemistry Research	2012	192
5	Indolizine: a biologically active moiety	Medicinal Chemistry Research	2014	188
6	Benzimidazole: a medicinally important heterocyclic moiety	Medicinal Chemistry Research	2012	186
7	Biological importance of imidazole nucleus in the new millennium	Medicinal Chemistry Research	2011	162
8	PASS-assisted exploration of new therapeutic potential of natural products	Medicinal Chemistry Research	2011	134
9	The synthetic and therapeutic expedition of isoxazole and its analogs	Medicinal Chemistry Research	2018	129
10	Indazole: a medicinally important heterocyclic moiety	Medicinal Chemistry Research	2012	127
11	Synthesis, DNA binding, hemolytic, and anti-cancer assays of curcumin I-based ligands and their ruthenium(III) complexes	Medicinal Chemistry Research	2013	107
12	Recent advances and therapeutic journey of coumarins: current status and perspectives	Medicinal Chemistry Research	2015	107
13	Design, synthesis, and antiviral activity of new 1H-1,2,3-triazole nucleoside ribavirin analogs	Medicinal Chemistry Research	2014	102
14	Anticancer properties of baicalein: a review	Medicinal Chemistry Research	2016	102
15	Potential applications of violacein: a microbial pigment	Medicinal Chemistry Research	2012	99
16	Synthesis, antioxidant evaluation, and quantitative structure–activity relationship studies of chalcones	Medicinal Chemistry Research	2011	98
17	Green approach towards the facile synthesis of dihydropyrano(c)chromene and pyrano[2,3-d]pyrimidine derivatives and their biological evaluation	Medicinal Chemistry Research	2013	97
18	Potent antimalarial activity of newly synthesized substituted chalcone analogs in vitro	Medicinal Chemistry Research	2009	93
19	Benzimidazole: a promising pharmacophore	Medicinal Chemistry Research	2013	93
20	Transition metals in organic synthesis - Part 83#: Synthesis and pharmacological potential of carbazoles	Medicinal Chemistry Research	2008	89
21	Synthesis and evaluation of in vitro antitubercular activity and antimicrobial activity of some novel 4H-chromeno[2,3-d]pyrimidine via 2-amino-4-phenyl-4H-chromene-3-carbonitriles	Medicinal Chemistry Research	2011	85
22	Petra, Osiris and Molinspiration (POM) together as a successful support in drug design: antibacterial activity and biopharmaceutical characterization of some azo Schiff bases	Medicinal Chemistry Research	2012	83
23	Quantitative structure–activity relationship (QSAR) studies as strategic approach in drug discovery	Medicinal Chemistry Research	2014	83
24	Synthesis, antibacterial and antifungal activities of naphthoquinone derivatives: a structure–activity relationship study	Medicinal Chemistry Research	2016	72
25	NATURAL COMPOUNDS IN DRUG DISCOVERY. BIOLOGICAL ACTIVITY AND NEW TRENDS IN THE CHEMISTRY OF ISOQUINOLINE ALKALOIDS	Medicinal Chemistry Research	2004	71
26	Transition metal complexes of thiosemicarbazones with quinoxaline hub: an emphasis on antidiabetic property	Medicinal Chemistry Research	2012	68
27	Synthesis and antimicrobial activity of some new 3–[5-(4-substituted) phenyl-1,3,4-oxadiazole-2yl]-2- styrylquinazoline-4(3H)-ones	Medicinal Chemistry Research	2008	67
28	Synthesis crystal structure of 2-methoxybenzoylhydrazones and evaluation of their α-glucosidase and urease inhibition potential	Medicinal Chemistry Research	2015	66
29	Piperamides and their derivatives as potential anti-trypanosomal agents	Medicinal Chemistry Research	2009	64
30	A rapid access to new coumarinyl chalcone and substituted chromeno[4,3-c]pyrazol-4(1H)-ones and their antibacterial and DPPH radical scavenging activities	Medicinal Chemistry Research	2011	64
31	Phytochemical, cytotoxic, hepatoprotective and antioxidant properties of Delonix regia leaves extract	Medicinal Chemistry Research	2013	64
32	Synthesis and anticancer activity of para-xylyl linked bis-benzimidazolium salts and respective Ag(I) N-heterocyclic carbene complexes	Medicinal Chemistry Research	2013	64
33	Synthesis, structure, anticancer, and antioxidant activity of para-xylyl linked bis-benzimidazolium salts and respective dinuclear Ag(I) N-heterocyclic carbene complexes (Part-II)	Medicinal Chemistry Research	2013	63
34	Synthesis and antimicrobial activity of novel quinoline derivatives bearing pyrazoline and pyridine analogues	Medicinal Chemistry Research	2017	63
35	Synthesis and antiviral activity of new 4-(phenylamino)/4-[(methylpyridin-2-yl)amino]-1-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acids derivatives	Medicinal Chemistry Research	2007	62
36	α-Glucosidase inhibitory and antioxidant properties and antidiabetic activity of Hypericum ascyron L.	Medicinal Chemistry Research	2011	62
37	Synthesis and antimicrobial activity of new pyridine derivatives-I	Medicinal Chemistry Research	2011	62
38	Molecular docking study on anticancer activity of plant-derived natural products	Medicinal Chemistry Research	2010	61
39	Synthesis, biological evaluation and molecular docking of novel coumarin incorporated triazoles as antitubercular, antioxidant and antimicrobial agents	Medicinal Chemistry Research	2016	61
40	Synthesis, antitumor and antioxidant evaluation of some new thiazole and thiophene derivatives incorporated coumarin moiety	Medicinal Chemistry Research	2012	60
41	Synthesis and anticancer activity evaluation of new 1,2,3-triazole-4-carboxamide derivatives	Medicinal Chemistry Research	2014	60
42	Screening of a library of 4-aryl/heteroaryl-4H-fused pyrans for xanthine oxidase inhibition: synthesis, biological evaluation and docking studies	Medicinal Chemistry Research	2015	60
43	Nrf2 activation through the inhibition of Keap1–Nrf2 protein–protein interaction	Medicinal Chemistry Research	2020	60
44	Synthesis and pharmacological evaluation of newer thiazolo [3,2-a] pyrimidines for anti-inflammatory and antinociceptive activity	Medicinal Chemistry Research	2010	59
45	Isonicotinic acid hydrazide derivatives: synthesis, antimicrobial activity, and QSAR studies	Medicinal Chemistry Research	2012	58
46	Inhibitory effect of Gymnema Montanum leaves on α-glucosidase activity and α-amylase activity and their relationship with polyphenolic content	Medicinal Chemistry Research	2010	57
47	Anti-HIV-1 and cytotoxicity studies of piperidyl-thienyl chalcones and their 2-pyrazoline derivatives	Medicinal Chemistry Research	2012	57
48	Osthole: an overview of its sources, biological activities, and modification development	Medicinal Chemistry Research	2021	57
49	Synthesis of coumarin-based 1,3,4-oxadiazol-2ylthio-N-phenyl/benzothiazolyl acetamides as antimicrobial and antituberculosis agents	Medicinal Chemistry Research	2013	56
50	Pyridazin-3(2H)-ones: the versatile pharmacophore of medicinal significance	Medicinal Chemistry Research	2013	56

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