6.5(top 5%)
impact factor
3.5K(top 5%)
papers
273.6K(top 2%)
citations
224(top 1%)
h-index
6.6(top 5%)
impact factor
4.5K
all documents
287.2K
doc citations
331(top 1%)
g-index

Top Articles

#TitleJournalYearCitations
1Role of nitric oxide synthesis in macrophage antimicrobial activityCurrent Opinion in Immunology19911,462
2Innate immunity: impact on the adaptive immune responseCurrent Opinion in Immunology19971,321
3Macrophages, innate immunity and cancer: balance, tolerance, and diversityCurrent Opinion in Immunology20101,270
4Origin, maturation and antigen presenting function of dendritic cellsCurrent Opinion in Immunology19971,239
5Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunityCurrent Opinion in Immunology20121,186
6New insights into cancer immunoediting and its three component phases—elimination, equilibrium and escapeCurrent Opinion in Immunology20141,163
7Role of the prophenoloxidase-activating system in invertebrate immunityCurrent Opinion in Immunology19981,146
8Danger signals: SOS to the immune systemCurrent Opinion in Immunology20011,106
9Antimicrobial peptides in mammalian and insect host defenceCurrent Opinion in Immunology1999935
10Reactive oxygen and reactive nitrogen intermediates in innate and specific immunityCurrent Opinion in Immunology2000812
11Cationic host defense (antimicrobial) peptidesCurrent Opinion in Immunology2006744
12Mitogen-activated protein kinase cascades and regulation of gene expressionCurrent Opinion in Immunology1996722
13NADPH oxidaseCurrent Opinion in Immunology2004719
14Alarmins: chemotactic activators of immune responsesCurrent Opinion in Immunology2005718
15Tlr4: central component of the sole mammalian LPS sensorCurrent Opinion in Immunology2000698
16Differentiation and function of Th17 T cellsCurrent Opinion in Immunology2007641
17The inflammasome: a danger sensing complex triggering innate immunityCurrent Opinion in Immunology2007640
18Toll-like receptors: key mediators of microbe detectionCurrent Opinion in Immunology2002632
19Defensins of vertebrate animalsCurrent Opinion in Immunology2002630
20Chemokines, leukocyte trafficking, and inflammationCurrent Opinion in Immunology1994623
21The complexity of disease signaling in ArabidopsisCurrent Opinion in Immunology2001616
22The Toll-receptor family and control of innate immunityCurrent Opinion in Immunology1999612
23Regulatory T cells in cancer immunotherapyCurrent Opinion in Immunology2014612
24The mannose receptor is a pattern recognition receptor involved in host defenseCurrent Opinion in Immunology1998608
25Toll signaling pathways in the innate immune responseCurrent Opinion in Immunology2000608
26The role of CD4+ T cell responses in antitumor immunityCurrent Opinion in Immunology1998593
27Chemokines in tissue-specific and microenvironment-specific lymphocyte homingCurrent Opinion in Immunology2000588
28The use of dendritic cells in cancer immunotherapyCurrent Opinion in Immunology2003582
29Myeloid-derived suppressor cell heterogeneity and subset definitionCurrent Opinion in Immunology2010579
30T cell anergy, exhaustion, senescence, and stemness in the tumor microenvironmentCurrent Opinion in Immunology2013576
31How Toll-like receptors signal: what we know and what we don’t knowCurrent Opinion in Immunology2006572
32Bcl-2-regulated apoptosis: mechanism and therapeutic potentialCurrent Opinion in Immunology2007560
33IL-33: an alarmin cytokine with crucial roles in innate immunity, inflammation and allergyCurrent Opinion in Immunology2014560
34Natural autoantibodiesCurrent Opinion in Immunology1995557
35Pattern-recognition receptors in plant innate immunityCurrent Opinion in Immunology2008555
36T cell defined tumor antigensCurrent Opinion in Immunology1997554
37Th17: the third member of the effector T cell trilogyCurrent Opinion in Immunology2007553
38IL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiationCurrent Opinion in Immunology2011547
39Colony-stimulating factor-1 in immunity and inflammationCurrent Opinion in Immunology2006542
40Transcriptional regulation of the IL-2 geneCurrent Opinion in Immunology1995539
41Adoptive cell therapy for the treatment of patients with metastatic melanomaCurrent Opinion in Immunology2009539
42Expanding the effector CD4 T-cell repertoire: the Th17 lineageCurrent Opinion in Immunology2006535
43Drosophila immunity: paths and patternsCurrent Opinion in Immunology2003532
44Aging of the innate immune systemCurrent Opinion in Immunology2010528
45Mammalian Toll-like receptorsCurrent Opinion in Immunology2003527
46The mononuclear phagocyte systemCurrent Opinion in Immunology2006524
47Recognition of Gram-negative bacteria and endotoxin by the innate immune systemCurrent Opinion in Immunology1999519
48Links between innate and adaptive immunity via type I interferonCurrent Opinion in Immunology2002518
49Recognition of microbial infection by Toll-like receptorsCurrent Opinion in Immunology2003509
50The CD47–SIRPα pathway in cancer immune evasion and potential therapeutic implicationsCurrent Opinion in Immunology2012507