| # | Title | Journal | Year | Citations |
|---|
| 1 | Overview of cell death signaling pathways | Cancer Biology and Therapy | 2005 | 1,047 |
| 2 | Cancer cell killing via ROS: To increase or decrease, that is the question | Cancer Biology and Therapy | 2008 | 694 |
| 3 | Identification of fibroblast heterogeneity in the tumor microenvironment | Cancer Biology and Therapy | 2006 | 603 |
| 4 | The PIK3CA gene is mutated with high frequency in human breast cancers | Cancer Biology and Therapy | 2004 | 594 |
| 5 | Current state of melanoma diagnosis and treatment | Cancer Biology and Therapy | 2019 | 462 |
| 6 | Cycling to Cancer with Cyclin D1 | Cancer Biology and Therapy | 2002 | 427 |
| 7 | Rhebbing up mTOR: New Insights on TSC1 and TSC2, and the Pathogenesis of Tuberous Sclerosis | Cancer Biology and Therapy | 2003 | 369 |
| 8 | Life and death of circulating cell-free DNA | Cancer Biology and Therapy | 2019 | 327 |
| 9 | miR-210 links hypoxia with cell cycle regulation and is deleted in human epithelial ovarian cancer | Cancer Biology and Therapy | 2008 | 324 |
| 10 | Notch Signaling in Cancer | Cancer Biology and Therapy | 2002 | 311 |
| 11 | The PERK/eIF2α/ATF4 module of the UPR in hypoxia resistance and tumor growth | Cancer Biology and Therapy | 2006 | 307 |
| 12 | Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer | Cancer Biology and Therapy | 2010 | 306 |
| 13 | The functional Interactions Between the MAPK and p53 Signaling Pathways | Cancer Biology and Therapy | 2004 | 288 |
| 14 | Wnt Signaling and Breast Cancer | Cancer Biology and Therapy | 2004 | 288 |
| 15 | MicroRNA miR-155 is a biomarker of early pancreatic neoplasia | Cancer Biology and Therapy | 2009 | 288 |
| 16 | Autophagy as a therapeutic target in cancer | Cancer Biology and Therapy | 2011 | 287 |
| 17 | Histological, molecular and functional subtypes of breast cancers | Cancer Biology and Therapy | 2010 | 285 |
| 18 | DNA methylation regulates microRNA expression | Cancer Biology and Therapy | 2007 | 283 |
| 19 | Rapamycins: Mechanisms of Action and Cellular Resistance | Cancer Biology and Therapy | 2003 | 282 |
| 20 | MicroRNA-21: A novel therapeutic target in human cancer | Cancer Biology and Therapy | 2010 | 282 |
| 21 | The Role of Environmental Carcinogens, Viruses, and Genetic | Cancer Biology and Therapy | 2002 | 280 |
| 22 | Autophagy and cancer therapy | Cancer Biology and Therapy | 2011 | 278 |
| 23 | Involvement of H2AX in the DNA Damage and Repair Response | Cancer Biology and Therapy | 2003 | 277 |
| 24 | The epithelial-mesenchymal tansition (EMT) and colorectal cancer progression | Cancer Biology and Therapy | 2005 | 266 |
| 25 | Long noncoding RNA MEG3 is downregulated in cervical cancer and affects cell proliferation and apoptosis by regulating miR-21 | Cancer Biology and Therapy | 2016 | 264 |
| 26 | Tumor infiltrating lymphocytes in ovarian cancer | Cancer Biology and Therapy | 2015 | 257 |
| 27 | Curcumin induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating akt and p38 mAPK | Cancer Biology and Therapy | 2007 | 249 |
| 28 | The role of the miR-200 family in epithelial-mesenchymal transition | Cancer Biology and Therapy | 2010 | 249 |
| 29 | Cross-talk of WNT and FGF signaling pathways at GSK3ß to regulate ß-catenin and SNAIL signaling cascades | Cancer Biology and Therapy | 2006 | 246 |
| 30 | Hsp60 expression, new locations, functions, and perspectives for cancer diagnosis and therapy | Cancer Biology and Therapy | 2008 | 230 |
| 31 | MALAT1 promotes the proliferation and metastasis of gallbladder cancer cells by activating the ERK/MAPK pathway | Cancer Biology and Therapy | 2014 | 229 |
| 32 | Molecular Pathogenesis of Rhabdomyosarcoma | Cancer Biology and Therapy | 2002 | 228 |
| 33 | N-acetylcysteine, reactive oxygen species and beyond | Cancer Biology and Therapy | 2010 | 225 |
| 34 | Activation of CDK4 Gene Expression in Human Breast Cancer Cells by the Brn-3b POU Family Transcription Factor | Cancer Biology and Therapy | 2004 | 222 |
| 35 | The role of Cdx proteins in intestinal development and cancer | Cancer Biology and Therapy | 2004 | 219 |
| 36 | EMT: A new vision of hypoxia promoting cancer progression | Cancer Biology and Therapy | 2011 | 218 |
| 37 | Chemotherapy induced DNA damage response | Cancer Biology and Therapy | 2013 | 216 |
| 38 | Tumor Microenvironment and the Response to Anticancer Therapy | Cancer Biology and Therapy | 2002 | 215 |
| 39 | HIF-1, An Oxygen and Metal Responsive Transcription Factor | Cancer Biology and Therapy | 2004 | 210 |
| 40 | Molecular mechanisms of resistance to the EGFR monoclonal antibody cetuximab | Cancer Biology and Therapy | 2011 | 209 |
| 41 | Glucose regulated proteins in cancer progression, Drug resistance and immunotherapy | Cancer Biology and Therapy | 2006 | 208 |
| 42 | Phase II trial of single agent Val-boroPro (talabostat) inhibiting fibroblast activation protein in patients with metastatic colorectal cancer | Cancer Biology and Therapy | 2007 | 207 |
| 43 | A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors | Cancer Biology and Therapy | 2011 | 205 |
| 44 | The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy | Cancer Biology and Therapy | 2012 | 205 |
| 45 | miRNA biogenesis: Biological impact in the development of cancer | Cancer Biology and Therapy | 2014 | 205 |
| 46 | MK-1775, a small molecule Wee1 inhibitor, enhances anti-tumor efficacy of various DNA-damaging agents, including 5-fluorouracil | Cancer Biology and Therapy | 2010 | 204 |
| 47 | The thioredoxin reductase/thioredoxin system: Novel redox targets for cancer therapy | Cancer Biology and Therapy | 2005 | 203 |
| 48 | Mitochondrial signaling in cell death via the Bcl-2 family | Cancer Biology and Therapy | 2010 | 203 |
| 49 | Identification of OATP1B3 as a high-affinity hepatocellular transporter of paclitaxel | Cancer Biology and Therapy | 2005 | 200 |
| 50 | Recurrent KRAS codon 146 mutations in human colorectal cancer | Cancer Biology and Therapy | 2006 | 200 |
