| # | Title | Journal | Year | Citations |
|---|
| 1 | Cisplatin: The first metal based anticancer drug | Bioorganic Chemistry | 2019 | 961 |
| 2 | Medicinal attributes of 1,2,3-triazoles: Current developments | Bioorganic Chemistry | 2017 | 631 |
| 3 | Effects of solvent polarity and solvent viscosity on the fluorescent properties of molecular rotors and related probes | Bioorganic Chemistry | 2005 | 348 |
| 4 | Ionization of Poly(ethylenimine) and Poly(allylamine) at Various pH′s | Bioorganic Chemistry | 1994 | 336 |
| 5 | Medicinal chemistry of indole derivatives: Current to future therapeutic prospectives | Bioorganic Chemistry | 2019 | 302 |
| 6 | The chemi- and bioluminescence of firefly luciferin: An efficient chemical production of electronically excited states | Bioorganic Chemistry | 1971 | 254 |
| 7 | Bovine Serum Albumin (BSA) coated iron oxide magnetic nanoparticles as biocompatible carriers for curcumin-anticancer drug | Bioorganic Chemistry | 2018 | 217 |
| 8 | Thiazolidinediones as antidiabetic agents: A critical review | Bioorganic Chemistry | 2018 | 212 |
| 9 | Some new nano-sized Fe(II), Cd(II) and Zn(II) Schiff base complexes as precursor for metal oxides: Sonochemical synthesis, characterization, DNA interaction, in vitro antimicrobial and anticancer activities | Bioorganic Chemistry | 2016 | 206 |
| 10 | A review on progression of epidermal growth factor receptor (EGFR) inhibitors as an efficient approach in cancer targeted therapy | Bioorganic Chemistry | 2020 | 203 |
| 11 | Effect of Ginger Constituents and Synthetic Analogues on Cyclooxygenase-2 Enzyme in Intact Cells | Bioorganic Chemistry | 2001 | 192 |
| 12 | Antioxidant and acetylcholinesterase inhibition properties of novel bromophenol derivatives | Bioorganic Chemistry | 2015 | 177 |
| 13 | Effect of kosmotropicity of ionic liquids on the enzyme stability in aqueous solutions | Bioorganic Chemistry | 2006 | 172 |
| 14 | Inhibitors of histone deacetylase as antitumor agents: A critical review | Bioorganic Chemistry | 2016 | 170 |
| 15 | Synthesis and differential antiproliferative activity of Biginelli compounds against cancer cell lines: Monastrol, oxo-monastrol and oxygenated analogues | Bioorganic Chemistry | 2006 | 169 |
| 16 | On the importance of orientation in general base catalysis by carboxylate | Bioorganic Chemistry | 1981 | 168 |
| 17 | Biomimetic polyene cyclizations | Bioorganic Chemistry | 1976 | 161 |
| 18 | Overview of recent developments of pyrazole derivatives as an anticancer agent in different cell line | Bioorganic Chemistry | 2020 | 157 |
| 19 | Synthesis, biological evaluation and molecular docking of novel pyrazole derivatives as potent carbonic anhydrase and acetylcholinesterase inhibitors | Bioorganic Chemistry | 2019 | 153 |
| 20 | Lignans of sesame: Purification methods, biological activities and biosynthesis – A review | Bioorganic Chemistry | 2013 | 147 |
| 21 | Isatin based Schiff bases as inhibitors of α-glucosidase: Synthesis, characterization, in vitro evaluation and molecular docking studies | Bioorganic Chemistry | 2015 | 147 |
| 22 | Biosynthesis of lepidopteran pheromones | Bioorganic Chemistry | 1984 | 146 |
| 23 | The origin of the RNA world: Co-evolution of genes and metabolism | Bioorganic Chemistry | 2007 | 146 |
| 24 | Synthesis and biological evaluation of novel tris-chalcones as potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and α-glycosidase inhibitors | Bioorganic Chemistry | 2019 | 145 |
| 25 | Recent advances in the chemistry of an old enzyme, urease | Bioorganic Chemistry | 1991 | 144 |
| 26 | The ATP-grasp enzymes | Bioorganic Chemistry | 2011 | 144 |
| 27 | Recent studies of nitrogen containing heterocyclic compounds as novel antiviral agents: A review | Bioorganic Chemistry | 2021 | 143 |
| 28 | “Induced-fit”-type complex formation of the model enzyme α-cyclodextrin | Bioorganic Chemistry | 1976 | 137 |
| 29 | Manganese complexes displaying superoxide dismutase activity: A balance between different factors | Bioorganic Chemistry | 2011 | 137 |
| 30 | Cathelicidin family of antimicrobial peptides: proteolytic processing and protease resistance | Bioorganic Chemistry | 2003 | 135 |
| 31 | Chalcone derivatives and their antibacterial activities: Current development | Bioorganic Chemistry | 2019 | 135 |
| 32 | The role of induced fit and conformational changes of enzymes in specificity and catalysis | Bioorganic Chemistry | 1988 | 133 |
| 33 | Novel 2-aminopyridine liganded Pd(II) N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure and bioactivity properties | Bioorganic Chemistry | 2019 | 132 |
| 34 | Phytosynthesis of silver nanoparticles using Mangifera indica flower extract as bioreductant and their broad-spectrum antibacterial activity | Bioorganic Chemistry | 2019 | 131 |
| 35 | Hydroxytyrosol lipophilic analogues: Enzymatic synthesis, radical scavenging activity and DNA oxidative damage protection | Bioorganic Chemistry | 2007 | 129 |
| 36 | History of the development of antifungal azoles: A review on structures, SAR, and mechanism of action | Bioorganic Chemistry | 2020 | 129 |
| 37 | The enzymes of sialic acid biosynthesis | Bioorganic Chemistry | 2005 | 127 |
| 38 | Synthetic and medicinal perspective of thiazolidinones: A review | Bioorganic Chemistry | 2017 | 127 |
| 39 | The first synthesis, carbonic anhydrase inhibition and anticholinergic activities of some bromophenol derivatives with S including natural products | Bioorganic Chemistry | 2019 | 127 |
| 40 | Triazinoindole analogs as potent inhibitors of α-glucosidase: Synthesis, biological evaluation and molecular docking studies | Bioorganic Chemistry | 2015 | 126 |
| 41 | The role of long noncoding RNA in major human disease | Bioorganic Chemistry | 2019 | 126 |
| 42 | Encapsulation of ciprofloxacin within modified xanthan gum- chitosan based hydrogel for drug delivery | Bioorganic Chemistry | 2019 | 126 |
| 43 | Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs | Bioorganic Chemistry | 2020 | 125 |
| 44 | Tumor inhibitors having potential for interaction with mercapto enzymes and/or coenzymes | Bioorganic Chemistry | 1977 | 121 |
| 45 | Novel antioxidant bromophenols with acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase inhibitory actions | Bioorganic Chemistry | 2017 | 121 |
| 46 | Recent advancements of coumarin-based anticancer agents: An up-to-date review | Bioorganic Chemistry | 2020 | 121 |
| 47 | Novel 1,2,4-triazole derivatives as potential anticancer agents: Design, synthesis, molecular docking and mechanistic studies | Bioorganic Chemistry | 2018 | 121 |
| 48 | Design, synthesis and anticancer evaluation of thieno[2,3-d]pyrimidine derivatives as dual EGFR/HER2 inhibitors and apoptosis inducers | Bioorganic Chemistry | 2019 | 119 |
| 49 | Design and synthesis of novel quinazolinone-1,2,3-triazole hybrids as new anti-diabetic agents: In vitro α-glucosidase inhibition, kinetic, and docking study | Bioorganic Chemistry | 2019 | 119 |
| 50 | Computational drug discovery and repurposing for the treatment of COVID-19: A systematic review | Bioorganic Chemistry | 2021 | 119 |
