| # | Title | Journal | Year | Citations |
|---|
| 1 | The Firmicutes/Bacteroidetes ratio of the human microbiota changes with age | BMC Microbiology | 2009 | 1,338 |
| 2 | Age-related changes in gut microbiota composition from newborn to centenarian: a cross-sectional study | BMC Microbiology | 2016 | 993 |
| 3 | Defining the healthy "core microbiome" of oral microbial communities | BMC Microbiology | 2009 | 989 |
| 4 | Evaluation of the bacterial diversity in the feces of cattle using 16S rDNA bacterial tag-encoded FLX amplicon pyrosequencing (bTEFAP) | BMC Microbiology | 2008 | 982 |
| 5 | Mycobacterium tuberculosis complex genetic diversity: mining the fourth international spoligotyping database (SpolDB4) for classification, population genetics and epidemiology | BMC Microbiology | 2006 | 900 |
| 6 | ITS as an environmental DNA barcode for fungi: an in silico approach reveals potential PCR biases | BMC Microbiology | 2010 | 792 |
| 7 | Association between body mass index and Firmicutes/Bacteroidetes ratio in an adult Ukrainian population | BMC Microbiology | 2017 | 720 |
| 8 | Non-classical protein secretion in bacteria | BMC Microbiology | 2005 | 663 |
| 9 | Survey of bacterial diversity in chronic wounds using Pyrosequencing, DGGE, and full ribosome shotgun sequencing | BMC Microbiology | 2008 | 634 |
| 10 | High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease | BMC Microbiology | 2011 | 596 |
| 11 | Fungal-specific PCR primers developed for analysis of the ITS region of environmental DNA extracts | BMC Microbiology | 2005 | 560 |
| 12 | Persisters: a distinct physiological state of E. coli | BMC Microbiology | 2006 | 528 |
| 13 | Critical aspects of using bacterial cell viability assays with the fluorophores SYTO9 and propidium iodide | BMC Microbiology | 2015 | 502 |
| 14 | Contribution of bacterial outer membrane vesicles to innate bacterial defense | BMC Microbiology | 2011 | 488 |
| 15 | Rapid bacterial colonization of low-density polyethylene microplastics in coastal sediment microcosms | BMC Microbiology | 2014 | 400 |
| 16 | A census of membrane-bound and intracellular signal transduction proteins in bacteria: bacterial IQ, extroverts and introverts | BMC Microbiology | 2005 | 398 |
| 17 | Indole is an inter-species biofilm signal mediated by SdiA | BMC Microbiology | 2007 | 388 |
| 18 | The truth about metagenomics: quantifying and counteracting bias in 16S rRNA studies | BMC Microbiology | 2015 | 388 |
| 19 | Structure, Genetics and Worldwide Spread of New Delhi Metallo-β-lactamase (NDM): a threat to public health | BMC Microbiology | 2017 | 387 |
| 20 | Dengue virus type 2: replication and tropisms in orally infected Aedes aegypti mosquitoes | BMC Microbiology | 2007 | 383 |
| 21 | RotaC: A web-based tool for the complete genome classification of group A rotaviruses | BMC Microbiology | 2009 | 365 |
| 22 | Comparative fecal metagenomics unveils unique functional capacity of the swine gut | BMC Microbiology | 2011 | 352 |
| 23 | Protein secretion systems in bacterial-host associations, and their description in the Gene Ontology | BMC Microbiology | 2009 | 346 |
| 24 | Lactobacillus plantarum MB452 enhances the function of the intestinal barrier by increasing the expression levels of genes involved in tight junction formation | BMC Microbiology | 2010 | 340 |
| 25 | Evaluation and selection of tandem repeat loci for a Brucella MLVA typing assay | BMC Microbiology | 2006 | 339 |
| 26 | Bacterial diversity at different stages of the composting process | BMC Microbiology | 2010 | 337 |
| 27 | Sampling and pyrosequencing methods for characterizing bacterial communities in the human gut using 16S sequence tags | BMC Microbiology | 2010 | 335 |
| 28 | Cloning of 16S rRNA genes amplified from normal and disturbed vaginal microflora suggests a strong association between Atopobium vaginae, Gardnerella vaginalis and bacterial vaginosis | BMC Microbiology | 2004 | 302 |
| 29 | Probiotic Lactobacillus reuteri biofilms produce antimicrobial and anti-inflammatory factors | BMC Microbiology | 2009 | 302 |
| 30 | Longitudinal analysis of the vaginal microflora in pregnancy suggests that L. crispatus promotes the stability of the normal vaginal microflora and that L. gasseri and/or L. iners are more conducive to the occurrence of abnormal vaginal microflora | BMC Microbiology | 2009 | 296 |
| 31 | Exposure to a social stressor disrupts the community structure of the colonic mucosa-associated microbiota | BMC Microbiology | 2014 | 292 |
| 32 | BACTIBASE second release: a database and tool platform for bacteriocin characterization | BMC Microbiology | 2010 | 291 |
| 33 | Bacterial diversity analysis of larvae and adult midgut microflora using culture-dependent and culture-independent methods in lab-reared and field-collected Anopheles stephensi-an Asian malarial vector | BMC Microbiology | 2009 | 287 |
| 34 | Endophytic fungal association via gibberellins and indole acetic acid can improve plant growth under abiotic stress: an example of Paecilomyces formosus LHL10 | BMC Microbiology | 2012 | 287 |
| 35 | Intestinal dysbiosis and reduced immunoglobulin-coated bacteria associated with coeliac disease in children | BMC Microbiology | 2010 | 282 |
| 36 | Comparison of oral microbiota in tumor and non-tumor tissues of patients with oral squamous cell carcinoma | BMC Microbiology | 2012 | 279 |
| 37 | Genes involved in arsenic transformation and resistance associated with different levels of arsenic-contaminated soils | BMC Microbiology | 2009 | 269 |
| 38 | Organic acid production in vitro and plant growth promotion in maize under controlled environment by phosphate-solubilizing fluorescent Pseudomonas | BMC Microbiology | 2009 | 267 |
| 39 | Molecular analysis of methanogenic archaea in the forestomach of the alpaca (Vicugna pacos) | BMC Microbiology | 2012 | 266 |
| 40 | The Francisella pathogenicity island protein IglA localizes to the bacterial cytoplasm and is needed for intracellular growth | BMC Microbiology | 2007 | 263 |
| 41 | Assessment of bacterial diversity in the cattle tick Rhipicephalus (Boophilus) microplusthrough tag-encoded pyrosequencing | BMC Microbiology | 2011 | 263 |
| 42 | Cinnamaldehyde and cinnamaldehyde derivatives reduce virulence in Vibrio spp. by decreasing the DNA-binding activity of the quorum sensing response regulator LuxR | BMC Microbiology | 2008 | 262 |
| 43 | An improved method for rapid generation of unmarked Pseudomonas aeruginosa deletion mutants | BMC Microbiology | 2005 | 259 |
| 44 | Comprehensive annotation of secondary metabolite biosynthetic genes and gene clusters of Aspergillus nidulans, A. fumigatus, A. niger and A. oryzae | BMC Microbiology | 2013 | 258 |
| 45 | Community terminal restriction fragment length polymorphisms reveal insights into the diversity and dynamics of leaf endophytic bacteria | BMC Microbiology | 2013 | 257 |
| 46 | Duodenal and faecal microbiota of celiac children: molecular, phenotype and metabolome characterization | BMC Microbiology | 2011 | 251 |
| 47 | Inhibitory effect of zingiber officinale towards Streptococcus mutans virulence and caries development: in vitro and in vivo studies | BMC Microbiology | 2015 | 250 |
| 48 | Classification of Myoviridae bacteriophages using protein sequence similarity | BMC Microbiology | 2009 | 245 |
| 49 | Plant growth promotion and Penicillium citrinum | BMC Microbiology | 2008 | 244 |
| 50 | Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses | BMC Microbiology | 2001 | 242 |
